相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
Li Han et al.
CELL STEM CELL (2023)
METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesis
Rui Su et al.
NATURE CELL BIOLOGY (2022)
Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2
Huanhuan Zhao et al.
CELL REPORTS (2022)
TET2 chemically modifies tRNAs and regulates tRNA fragment levels
Chongsheng He et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)
Bone marrow niche ATP levels determine leukemia-initiating cell activity via P2X7 in leukemic models
Xiaoxiao He et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Acute myeloid leukemia: current progress and future directions
Hagop Kantarjian et al.
BLOOD CANCER JOURNAL (2021)
RNA modifications in hematopoietic malignancies: a new research frontier
Ying Qing et al.
BLOOD (2021)
Treatment-induced arteriolar revascularization and miR-126 enhancement in bone marrow niche protect leukemic stem cells in AML
Bin Zhang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)
TET-mediated 5-methylcytosine oxidation in tRNA promotes translation
Hui Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
CXCL12/CXCR4 signal transduction in diseases and its molecular approaches in targeted-therapy
Ashraf Mousavi
IMMUNOLOGY LETTERS (2020)
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
Huilin Huang et al.
CANCER CELL (2020)
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
Chao Shen et al.
CELL STEM CELL (2020)
Treatment of Relapsed Acute Myeloid Leukemia
Felicitas Thol et al.
CURRENT TREATMENT OPTIONS IN ONCOLOGY (2020)
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
Rui Su et al.
CANCER CELL (2020)
Loss of TET2 Affects Proliferation and Drug Sensitivity through Altered Dynamics of Cell-State Transitions
Leanna Morinishi et al.
CELL SYSTEMS (2020)
Tetraspanin Scaffold Proteins Function as Key Regulators of Hematopoietic Stem Cells
Victoria D. Balise et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation
Jie Lan et al.
NATURE COMMUNICATIONS (2020)
Ex vivo cultures and drug testing of primary acute myeloid leukemia samples: Current techniques and implications for experimental design and outcome
D. G. J. Cucchi et al.
DRUG RESISTANCE UPDATES (2020)
The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML
David Vetrie et al.
NATURE REVIEWS CANCER (2020)
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
Peter van Galen et al.
CELL (2019)
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells
Puneet Agarwal et al.
CELL STEM CELL (2019)
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
Yue Huang et al.
CANCER CELL (2019)
Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA
Li-Sheng Zhang et al.
MOLECULAR CELL (2019)
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
Xin Chen et al.
NATURE CELL BIOLOGY (2019)
RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay
Ying Yang et al.
MOLECULAR CELL (2019)
Antibody cross-reactivity accounts for widespread appearance of m1A in 5′UTRs
Anya V. Grozhik et al.
NATURE COMMUNICATIONS (2019)
Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche
Xiaoxin Hao et al.
CELL METABOLISM (2019)
BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles
Frederik Otzen Bagger et al.
NUCLEIC ACIDS RESEARCH (2019)
Very poor long-term survival in past and more recent studies for relapsed AML patients: The ECOG-ACRIN experience
Chezi Ganzel et al.
AMERICAN JOURNAL OF HEMATOLOGY (2018)
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling
Rui Su et al.
CELL (2018)
Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation
Qicong Shen et al.
NATURE (2018)
RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells
Diana Guallar et al.
NATURE GENETICS (2018)
The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cells
Chelsea A. Saito-Reis et al.
MOLECULAR BIOLOGY OF THE CELL (2018)
Functional genomic landscape of acute myeloid leukaemia
Jeffrey W. Tyner et al.
NATURE (2018)
Targeting Leukemia Stem Cells in the Bone Marrow Niche
Sarah K. Tasian et al.
BIOMEDICINES (2018)
Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs
Carine Legrand et al.
GENOME RESEARCH (2017)
Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice
Bing He et al.
MOLECULAR MEDICINE REPORTS (2017)
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells
Feng Pan et al.
NATURE COMMUNICATIONS (2017)
5-methylcytosine promotes mRNA export-NSUN2 as the methyltransferase and ALYREF as an m5C reader
Xin Yang et al.
CELL RESEARCH (2017)
Therapeutic targeting of acute myeloid leukemia stem cells
Daniel A. Pollyea et al.
BLOOD (2017)
Biology and relevance of human acute myeloid leukemia stem cells
Daniel Thomas et al.
BLOOD (2017)
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase
Zejuan Li et al.
CANCER CELL (2017)
meRanTK: methylated RNA analysis ToolKit
Dietmar Rieder et al.
BIOINFORMATICS (2016)
Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles
Megan A. Hatlen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherin
K. D. Marjon et al.
ONCOGENE (2016)
High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells
Chongsheng He et al.
MOLECULAR CELL (2016)
Transcriptome-wide distribution and function of RNA hydroxymethylcytosine
Benjamin Delatte et al.
SCIENCE (2016)
Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia
Hyog Young Kwon et al.
CELL STEM CELL (2015)
Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis
Kasper D. Rasmussen et al.
GENES & DEVELOPMENT (2015)
Acute Myeloid Leukemia
Hartmut Doehner et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Tet-Mediated Formation of 5-Hydroxymethylcytosine in RNA
Lijuan Fu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
N6-methyladenosine-dependent regulation of messenger RNA stability
Xiao Wang et al.
NATURE (2014)
Regulation of TET Protein Stability by Calpains
Yu Wang et al.
CELL REPORTS (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy
Benjamin Boyerinas et al.
BLOOD (2013)
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration
Helga Thorvaldsdottir et al.
BRIEFINGS IN BIOINFORMATICS (2013)
Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation
Lulu Hu et al.
CELL (2013)
TET1 plays an essential oncogenic role in MLL-rearranged leukemia
Hao Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Suppressor of Cytokine Signaling 6 (SOCS6) Negatively Regulates Flt3 Signal Transduction through Direct Binding to Phosphorylated Tyrosines 591 and 919 of Flt3
Julhash U. Kazi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Landscape of TET2 mutations in acute myeloid leukemia
S. Weissmann et al.
LEUKEMIA (2012)
The role of mutations in epigenetic regulators in myeloid malignancies
Alan H. Shih et al.
NATURE REVIEWS CANCER (2012)
The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34+ hematopoietic stem and progenitor cells
Kam Tong Leung et al.
BLOOD (2011)
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
Zhe Li et al.
BLOOD (2011)
TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics
Wen-Chien Chou et al.
BLOOD (2011)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis
Cyril Quivoron et al.
CANCER CELL (2011)
Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
Kelly Moran-Crusio et al.
CANCER CELL (2011)
Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting
Marina Y. Konopleva et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
CXCR4 Expression on Activated B Cells Is Downregulated by CD63 and IL-21
Nobuya Yoshida et al.
JOURNAL OF IMMUNOLOGY (2011)
Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias
R. Itzykson et al.
LEUKEMIA (2011)
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
Myunggon Ko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
Yu-Fei He et al.
SCIENCE (2011)
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
Shinsuke Ito et al.
SCIENCE (2011)
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
Myunggon Ko et al.
NATURE (2010)
Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML
Zhihong Zeng et al.
BLOOD (2009)
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
Bruno Nervi et al.
BLOOD (2009)
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
Omar Abdel-Wahab et al.
BLOOD (2009)
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
Yifang Hu et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
A. Tefferi et al.
LEUKEMIA (2009)
Mutation inTET2in Myeloid Cancers
NEW ENGLAND JOURNAL OF MEDICINE (2009)
A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells
Eric Campeau et al.
PLOS ONE (2009)
DNA digestion to deoxyribonucleo side: A simplified one-step procedure
Eoin P. Quinlivan et al.
ANALYTICAL BIOCHEMISTRY (2008)
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
Andrei V. Krivtsov et al.
NATURE (2006)
A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis
Ming Yan et al.
NATURE MEDICINE (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
X-tile: A new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization
RL Camp et al.
CLINICAL CANCER RESEARCH (2004)
Lentivirus-delivered stable gene silencing by RNAi in primary cells
SA Stewart et al.
RNA (2003)
分享论文
