相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Quantitative prediction of OATP-mediated disposition and biliary clearance using human liver chimeric mice
Taiji Miyake et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2023)
Comparison of docetaxel pharmacokinetics between castration-resistant and hormone-sensitive metastatic prostate cancer patients
Marit A. C. Vermunt et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2022)
Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
Florian Klammers et al.
DRUG METABOLISM AND DISPOSITION (2022)
Planning experiments: Updated guidance on experimental design and analysis and their reporting III
Michael J. Curtis et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans
Flavia Storelli et al.
PHARMACOLOGY & THERAPEUTICS (2022)
Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
Bo Feng et al.
DRUG METABOLISM AND DISPOSITION (2021)
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2021)
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2021)
Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism
Seigo Sanoh et al.
XENOBIOTICA (2020)
ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
Elliott Lilley et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Nathalie Percie du Sert et al.
PLOS BIOLOGY (2020)
Effect of Rifampicin on the Plasma Concentrations of Bile Acid-O-Sulfates in Monkeys and Human Liver-Transplanted Chimeric Mice With or Without Bile Flow Diversion
Issey Takehara et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach
Dan-Dan Tian et al.
DRUG METABOLISM AND DISPOSITION (2019)
Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats
Taiji Miyake
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2019)
Chimeric mice with humanized liver: Application in drug metabolism and pharmacokinetics studies for drug discovery
Yoichi Naritomi et al.
DRUG METABOLISM AND PHARMACOKINETICS (2018)
Organic Anion-Transporting Polypeptide (OATP)-Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver
Masashi Uchida et al.
DRUG METABOLISM AND DISPOSITION (2018)
Projecting ADME Behavior and Drug-Drug Interactions in Early Discovery and Development: Application of the Extended Clearance Classification System
Ayman F. El-Kattan et al.
PHARMACEUTICAL RESEARCH (2016)
Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
Hai-Feng Zhang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Comparative Proteomic Analysis of Human Liver Tissue and Isolated Hepatocytes with a Focus on Proteins Determining Drug Exposure
Anna Vildhede et al.
JOURNAL OF PROTEOME RESEARCH (2015)
Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS)
Manthena V. Varma et al.
PHARMACEUTICAL RESEARCH (2015)
Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice
Chise Tateno et al.
PLOS ONE (2015)
Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver
Kota Kato et al.
DRUG METABOLISM AND DISPOSITION (2015)
A Useful Model Capable of Predicting the Clearance of Cytochrome P450 3A4 (CYP3A4) Substrates in Humans: Validity of CYP3A4 Transgenic Mice Lacking Their Own Cyp3a Enzymes
Tetsuya Mitsui et al.
DRUG METABOLISM AND DISPOSITION (2014)
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Ulrich M. Zanger et al.
PHARMACOLOGY & THERAPEUTICS (2013)
A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes
Cornelia M. Smith et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
In Silico, In Vitro and In Situ Models to Assess Interplay Between CYP3A and P-gp
Daniel R. Mudra et al.
CURRENT DRUG METABOLISM (2011)
Biodistribution and radiation dosimetry of 11C-labelled docetaxel in cancer patients
Astrid A. M. van der Veldt et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2010)
Synergism of glucocorticoid hormone with growth hormone for female-specific mouse Cyp3a44 gene expression
Tsutomu Sakuma et al.
DRUG METABOLISM AND DISPOSITION (2008)
Gender Has a Small but Statistically Significant Effect on Clearance of CYP3A Substrate Drugs
David J. Greenblatt et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2008)
A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome P450 phenotypic data
Chuang Lu et al.
DRUG METABOLISM AND DISPOSITION (2007)
Determination of the hepatocellularity number for human, dog, rabbit, rat and mouse livers from protein concentration measurements
Anna-Karin Sohlenius-Sternbeck
TOXICOLOGY IN VITRO (2006)
The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions
RS Obach et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Alprazolam as a probe for CYP3A using a single blood sample:: pharmacokinetics of parent drug, and of α- and 4-hydroxy metabolites in healthy subjects
A Wennerholm et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2005)
The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice
EM Kemper et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2004)
Expression of the human CYP3A4 gene in the small intestine of transgenic mice:: In vitro metabolism and pharmacokinetics of midazolam
CP Granvil et al.
DRUG METABOLISM AND DISPOSITION (2003)
Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones
T Sakuma et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)