Acceptability and optimisation of resources to support antidepressant cessation: a qualitative think-aloud study with patients in Australian primary care

Review Nursing

Experience of antidepressant use and discontinuation: A qualitative synthesis of the evidence

Marie Crowe et al.

Summary: This study reveals the need for providing individuals seeking treatment for depression with treatment options and evidence-based information about antidepressants to empower them to make informed choices.

JOURNAL OF PSYCHIATRIC AND MENTAL HEALTH NURSING (2023)

添加到收藏夹

Article Primary Health Care

Withdrawing from SSRI antidepressants: advice for primary care

Emilia G. Palmer et al.

BRITISH JOURNAL OF GENERAL PRACTICE (2023)

添加到收藏夹

Review Clinical Neurology

Estimating Risk of Antidepressant Withdrawal from a Review of Published Data

Mark Abie Horowitz et al.

Summary: The brain's adaptation to drugs can predict withdrawal symptoms upon cessation. Physical dependence to antidepressants may occur in some patients, and factors such as duration of use, dosage, and specific drugs can influence the risk of withdrawal effects. Further research is needed to improve prediction tools and understand the adaptability of long-term antidepressant use.

CNS DRUGS (2023)

添加到收藏夹

Article Primary Health Care

Antidepressant Tapering Is Not Routine But Could Be

James Phelps et al.

Summary: When discontinuing antidepressants, it is important to carefully taper the dose in order to minimize withdrawal symptoms. However, it is difficult to determine which patients will struggle without a taper. A one-size-fits-all taper approach is recommended.

JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE (2023)

添加到收藏夹

Article Psychiatry

Distinguishing relapse from antidepressant withdrawal: clinical practice and antidepressant discontinuation studies

Mark Abie Horowitz et al.

Summary: Withdrawal symptoms from antidepressants are common and can be severe. It is difficult to distinguish withdrawal from relapse due to overlapping symptoms. However, by considering the timing of onset, the association of psychological and physical symptoms, the response to reinstatement, and the pattern of symptoms, it is possible to differentiate withdrawal from relapse. Current evidence for the relapse prevention properties of antidepressants is limited and needs re-evaluation.

BJPSYCH ADVANCES (2022)

添加到收藏夹

Article Primary Health Care

Process evaluation of the Safer Prescribing and Care for the Elderly (SPACE) cluster randomised controlled trial in New Zealand general practice

Katharine Ann Wallis et al.

Summary: This process evaluation examines the participation, intervention uptake, and impact on GPs in the Safer Prescribing and Care for the Elderly (SPACE) trial. The study found challenges in recruiting and engaging general practices, as well as variations in GP attitudes towards sending letters to high-risk prescribing patients.

JOURNAL OF PRIMARY HEALTH CARE (2022)

添加到收藏夹

Article Primary Health Care

Long-term antidepressant use in general practice: a qualitative study of GPs' views on discontinuation

Maria Donald et al.

Summary: Australian GPs were interviewed to understand their perspectives on long-term antidepressant prescribing and discontinuation. The study revealed that GPs carefully consider the decision to discontinue, and collaborate with patients to provide support before, during, and after discontinuation. The findings suggest that interventions to address long-term antidepressant use should take into account the complex decision-making process and the need for tailored support for both GPs and patients.

BRITISH JOURNAL OF GENERAL PRACTICE (2021)

添加到收藏夹

Article Medicine, General & Internal

A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance

Kathryn Skivington et al.

Summary: The UK Medical Research Council's new guidance framework for developing and evaluating complex interventions, commissioned jointly with the National Institute for Health Research, considers recent developments in theory and methods to maximize research efficiency, use, and impact.

BMJ-BRITISH MEDICAL JOURNAL (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Successful use of tapering strips for hyperbolic reduction of antidepressant dose: a cohort study

Peter C. Groot et al.

Summary: The study confirms the effectiveness of tapering strips in addressing antidepressant withdrawal symptoms. The real-world effectiveness of tapering strips is 70%, with the majority of patients able to successfully discontinue their medication using an average of two strips over a period of approximately 56 days.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2021)

添加到收藏夹

Article Medicine, Research & Experimental