相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Apolipoprotein E ε4 disrupts oligodendrocyte differentiation by interfering with astrocyte-derived lipid transport
Kingston King-Shi Mok et al.
JOURNAL OF NEUROCHEMISTRY (2023)
Oligodendrocytes take centre stage in APOE4-linked Alzheimer disease
Katie Kingwell
NATURE REVIEWS DRUG DISCOVERY (2023)
Total Cholesterol and APOE-Related Risk for Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative
Michelle M. Dunk et al.
JOURNAL OF ALZHEIMERS DISEASE (2022)
APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes
Sherida M. de Leeuw et al.
STEM CELL REPORTS (2022)
Apolipoprotein E and Alzheimer's Disease: Findings, Hypotheses, and Potential Mechanisms
Nicole Koutsodendris et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2022)
APOE Antibody Inhibits Aβ-Associated Tau Seeding and Spreading in a Mouse Model
Maud Gratuze et al.
ANNALS OF NEUROLOGY (2022)
The detrimental effects of APOE4 on risk for Alzheimer's disease may result from altered dendritic spine density, synaptic proteins, and
Lisa R. Taxier et al.
NEUROBIOLOGY OF AGING (2022)
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Joel W. Blanchard et al.
NATURE (2022)
APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-?B activation
Laurie Arnaud et al.
CELL REPORTS (2022)
Prospective biomarkers of Alzheimer's disease: A systematic review and meta-analysis
Rui-Xian Li et al.
AGEING RESEARCH REVIEWS (2022)
Eicosanoid lipidome activation in post-mortem brain tissues of individuals with APOE4 and Alzheimer's dementia
Brandon Ebright et al.
ALZHEIMERS RESEARCH & THERAPY (2022)
The influence of stimulus eccentricity on prosaccade outcomes in patients with Alzheimer's Disease dementia at an early stage and amnestic mild cognitive impairment
Hatice Eraslan Boz et al.
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY (2022)
2022 Alzheimer's disease facts and figures
Joseph Gaugler et al.
ALZHEIMERS & DEMENTIA (2022)
Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis
Yun Chen et al.
NEURON (2021)
APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function
Monica Xiong et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Apolipoprotein Mimetic Peptides: Potential New Therapies for Cardiovascular Diseases
Anna Wolska et al.
CELLS (2021)
Repetitive Transcranial Magnetic Stimulation for Alzheimer's Disease Based on Apolipoprotein E Genotyping: Protocol for a Randomized Controlled Study
Naili Wei et al.
FRONTIERS IN AGING NEUROSCIENCE (2021)
Gene-Specific DNA Methylation Linked to Postoperative Cognitive Dysfunction in Apolipoprotein E3 and E4 Mice
Katie J. Schenning et al.
JOURNAL OF ALZHEIMERS DISEASE (2021)
Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro
Jaclyn Iannucci et al.
CURRENT ISSUES IN MOLECULAR BIOLOGY (2021)
Medium-chain triglycerides improved cognition and lipid metabolomics in mild to moderate Alzheimer's disease patients with APOE4-/-: A double-blind, randomized, placebo-controlled crossover trial
Qing Xu et al.
CLINICAL NUTRITION (2020)
Lipids and Alzheimer's Disease
Yu-Chia Kao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
Iris L. Uijen et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
Safety and Efficacy of Donepezil 10 mg/day in Patients with Mild to Moderate Alzheimer's Disease
Jianping Jia et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study
Eric M. Reiman et al.
NATURE COMMUNICATIONS (2020)
Effects of low- and high-intensity physical exercise on physical and cognitive function in older persons with dementia: a randomized controlled trial
L. M. J. Sanders et al.
ALZHEIMERS RESEARCH & THERAPY (2020)
APOE epsilon 4 and the Influence of Sex, Age, Vascular Risk Factors, and Ethnicity on Cognitive Decline
Steve R. Makkar et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)
ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes
Abby Keable et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial
Isabella C. Arellanes et al.
EBIOMEDICINE (2020)
Diagnosis Test Meta-Analysis for Apolipoprotein E in Alzheimer's Disease
Xuan Xiong et al.
DISEASE MARKERS (2020)
Relationship between the Presence of the ApoE ε4 Allele and EEG Complexity along the Alzheimer's Disease Continuum
Victor Gutierrez-de Pablo et al.
SENSORS (2020)
Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial
Gary E. Gibson et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids
Jing Zhao et al.
NATURE COMMUNICATIONS (2020)
Could Alzheimer's Disease Originate in the Periphery and If So How So?
Gerwyn Morris et al.
MOLECULAR NEUROBIOLOGY (2019)
Understanding the Role of ApoE Fragments in Alzheimer's Disease
Sonia Sanz Munoz et al.
NEUROCHEMICAL RESEARCH (2019)
Role of cholesterol and sphingolipids in brain development and neurological diseases
Ghulam Hussain et al.
LIPIDS IN HEALTH AND DISEASE (2019)
EEG evidence of compensatory mechanisms in preclinical Alzheimer's disease
Sinead Gaubert et al.
BRAIN (2019)
Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies
Yu Yamazaki et al.
NATURE REVIEWS NEUROLOGY (2019)
APOE ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia
Saira Saeed Mirza et al.
NEUROLOGY (2019)
Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease
A. David Marais
PATHOLOGY (2019)
Risk factors for Alzheimer's disease
Richard A. Armstrong
FOLIA NEUROPATHOLOGICA (2019)
APOE-epsilon 4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies
Usman Saeed et al.
ALZHEIMERS & DEMENTIA (2018)
Changes in regional cerebral blood flow associated with a 45 day course of the ketogenic agent, caprylidene, in patients with mild to moderate Alzheimer's disease: Results of a randomized, double-blinded, pilot study
Nare Torosyan et al.
EXPERIMENTAL GERONTOLOGY (2018)
Dual-Task Gait and Alzheimer's Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study
Heather E. Whitson et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
A flow cytometry-based in vitro assay reveals that formation of apolipoprotein E (ApoE)-amyloid beta complexes depends on ApoE isoform and cell type
Eleanna Kara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation
Fan Liao et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector
Chengzhong Wang et al.
NATURE MEDICINE (2018)
The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype
Olga Pletnikova et al.
NEUROBIOLOGY OF AGING (2018)
Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease
Yen Ying Lim et al.
JAMA NEUROLOGY (2018)
Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention A Subgroup Analysis of a Randomized Clinical Trial
Alina Solomon et al.
JAMA NEUROLOGY (2018)
Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers
Qiushan Tao et al.
JAMA NETWORK OPEN (2018)
Astrocyte lipid metabolism is critical for synapse development and function in vivo
Anne-Lieke F. van Deijk et al.
GLIA (2017)
Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease
Jill K. Morris et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Oligodendroglial myelination requires astrocyte-derived lipids
Nutabi Camargo et al.
PLOS BIOLOGY (2017)
Interindividual variability in response to continuous theta-burst stimulation in healthy adults
Ali Jannati et al.
CLINICAL NEUROPHYSIOLOGY (2017)
APOE ε4 allele elevates the expressions of inflammatory factors and promotes Alzheimer's disease progression: A comparative study based on Han and She populations in the Wenzhou area
Yin-Ying Fan et al.
BRAIN RESEARCH BULLETIN (2017)
Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with dietary factors
Patricia Huebbe et al.
AGEING RESEARCH REVIEWS (2017)
Cilostazol as an add-on therapy for patients with Alzheimer's disease in Taiwan: a case control study
Shu-Yu Tai et al.
BMC NEUROLOGY (2017)
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion
Yu-Wen Alvin Huang et al.
CELL (2017)
Multiple Effect of APOE Genotype on Clinical and Neuroimaging Biomarkers Across Alzheimer's Disease Spectrum
Ying Liu et al.
MOLECULAR NEUROBIOLOGY (2016)
Phenome-Wide Association Studies as a Tool to Advance Precision Medicine
Joshua C. Denny et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 17 (2016)
Central Nervous System Lipoproteins ApoE and Regulation of Cholesterol Metabolism
Robert W. Mahley
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Impaired Autophagy in APOE4 Astrocytes
Shira Simonovitch et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Association between Cerebrospinal Fluid Biomarkers for Alzheimer's Disease, APOE Genotypes and Auditory Verbal Learning Task in Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's Disease
Monika Mandecka et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Butyrylcholinesterase K and Apolipoprotein E-epsilon 4 Reduce the Age of Onset of Alzheimer's Disease, Accelerate Cognitive Decline, and Modulate Donepezil Response in Mild Cognitively Impaired Subjects
Louis De Beaumont et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Unravelling the human genome-phenome relationship using phenome-wide association studies
William S. Bush et al.
NATURE REVIEWS GENETICS (2016)
Apolipoprotein E Genotype Linked to Spatial Gait Characteristics: Predictors of Cognitive Dual Task Gait Change
Rebecca K. MacAulay et al.
PLOS ONE (2016)
Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
Won-Suk Chung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific
Ioannis Dafnis et al.
SCIENTIFIC REPORTS (2016)
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease
Luke W. Bonham et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2016)
APOEε2 is associated with milder clinical and pathological Alzheimer disease
Alberto Serrano-Pozo et al.
ANNALS OF NEUROLOGY (2015)
CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease
Fathia Djelti et al.
BRAIN (2015)
Effects of COMT, DRD2, BDNF, and APOE Genotypic Variation on Treatment Efficacy and Cognitive Side Effects of Electroconvulsive Therapy
Chad A. Bousman et al.
JOURNAL OF ECT (2015)
Cholesterol metabolism and homeostasis in the brain
Juan Zhang et al.
PROTEIN & CELL (2015)
Long-Acting Intranasal Insulin Detemir Improves Cognition for Adults with Mild Cognitive Impairment or Early-Stage Alzheimer's Disease Dementia (vol 44, pg 897, 2015)
Amy Claxton et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's disease
Daniel M. Michaelson
ALZHEIMERS & DEMENTIA (2014)
Sex Modifies the APOE-Related Risk of Developing Alzheimer Disease
Andre Altmann et al.
ANNALS OF NEUROLOGY (2014)
A Single-Dose Pilot Trial of Intranasal Rapid-Acting Insulin in Apolipoprotein E4 Carriers with Mild-Moderate Alzheimer's Disease
Michael H. Rosenbloom et al.
CNS DRUGS (2014)
Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition
Gustavo A. Rodriguez et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis
Fan Liao et al.
JOURNAL OF NEUROSCIENCE (2014)
Apolipoprotein E genotype, gender and age modulate connectivity of the hippocampus in healthy adults
Verena Heise et al.
NEUROIMAGE (2014)
Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
Stephen Salloway et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Apolipoprotein E Genotype and the Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers for Alzheimer Disease
Ronald Lautner et al.
JAMA PSYCHIATRY (2014)
Effect of CYP2D6*10 and APOE Polymorphisms on the Efficacy of Donepezil in Patients With Alzheimer's Disease
Yuan Zhong et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2013)
The DLK signalling pathway-a double-edged sword in neural development and regeneration
Andrea Tedeschi et al.
EMBO REPORTS (2013)
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
Chia-Chan Liu et al.
NATURE REVIEWS NEUROLOGY (2013)
The Apolipoprotein-E-Mimetic COG112 Protects Amyloid Precursor Protein Intracellular Domain-Overexpressing Animals from Alzheimer's Disease-Like Pathological Features
Kaushik Ghosal et al.
NEURODEGENERATIVE DISEASES (2013)
Neuroimaging biomarkers for Alzheimer's disease in asymptomatic APOE4 carriers
G. Chetelat et al.
REVUE NEUROLOGIQUE (2013)
Apolipoprotein E genotypes and neuropsychiatric symptoms and syndromes in late-onset Alzheimer's disease
Francesco Panza et al.
AGEING RESEARCH REVIEWS (2012)
Plasma Signaling Proteins in Persons at Genetic Risk for Alzheimer Disease Influence of APOE Genotype
John M. Ringman et al.
ARCHIVES OF NEUROLOGY (2012)
Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition
Denise Head et al.
ARCHIVES OF NEUROLOGY (2012)
Response to Rivastigmine Transdermal Patch or Memantine plus Rivastigmine Patch is affected by Apolipoprotein E Genotype in Alzheimer Patients
Hyun Jeong Han et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2012)
APOE genotype alters glial activation and loss of synaptic markers in mice
Yuangui Zhu et al.
GLIA (2012)
Small Molecule Structure Correctors Abolish Detrimental Effects of Apolipoprotein E4 in Cultured Neurons
Hung-Kai Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis
Jungsu Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Gender Modulates the APOE ε4 Effect in Healthy Older Adults: Convergent Evidence from Functional Brain Connectivity and Spinal Fluid Tau Levels
Jessica S. Damoiseaux et al.
JOURNAL OF NEUROSCIENCE (2012)
Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid β Peptide
Tadafumi Hashimoto et al.
JOURNAL OF NEUROSCIENCE (2012)
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Robert D. Bell et al.
NATURE (2012)
APOE-Mimetic Peptides Reduce Behavioral Deficits, Plaques and Tangles in Alzheimer's Disease Transgenics
M. P. Vitek et al.
NEURODEGENERATIVE DISEASES (2012)
Hilar GABAergic Interneuron Activity Controls Spatial Learning and Memory Retrieval
Yaisa Andrews-Zwilling et al.
PLOS ONE (2012)
Resting-State Network Disruption and APOE Genotype in Alzheimer's Disease: A lagged Functional Connectivity Study
Leonides Canuet et al.
PLOS ONE (2012)
Reduced Hippocampal Volume in Healthy Young ApoE4 Carriers: An MRI Study
Laurence O'Dwyer et al.
PLOS ONE (2012)
ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models
Paige E. Cramer et al.
SCIENCE (2012)
Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimer's Disease: Two Phase 3 Studies
C. Harrington et al.
CURRENT ALZHEIMER RESEARCH (2011)
Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease
C. Dirk Keene et al.
CURRENT OPINION IN NEUROBIOLOGY (2011)
Presence of ApoE epsilon 4 Allele Associated with Thinner Frontal Cortex in Middle Age
Christine Fennema-Notestine et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice
Rebekah C. Mannix et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study
Henryk Barthel et al.
LANCET NEUROLOGY (2011)
Isoform-specific proteolysis of apolipoprotein-E in the brain
David A. Elliott et al.
NEUROBIOLOGY OF AGING (2011)
APOE4 is associated with greater atrophy of the hippocampal formation in Alzheimer's disease
Michela Pievani et al.
NEUROIMAGE (2011)
Chronic divalproex sodium use and brain atrophy in Alzheimer disease
A. S. Fleisher et al.
NEUROLOGY (2011)
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance
Joseph M. Castellano et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Temporal lobe functional activity and connectivity in young adult APOE ε4 carriers
Nancy A. Dennis et al.
ALZHEIMERS & DEMENTIA (2010)
Effects of Hormone Therapy on Depressive Symptoms and Cognitive Functions in Women With Alzheimer Disease: A 12 Month Randomized, Double-Blind, Placebo-Controlled Study of Low-Dose Estradiol and Norethisterone
Arnhild Valen-Sendstad et al.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2010)
Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer's Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study
Michael Gold et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2010)
Pre-Clinical Detection of Alzheimer's Disease Using FDG-PET, with or without Amyloid Imaging
Lisa Mosconi et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42
Ioannis Dafnis et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice
Yaisa Andrews-Zwilling et al.
JOURNAL OF NEUROSCIENCE (2010)
Cortical thickness is associated with different apolipoprotein E genotypes in healthy elderly adults
Ming Fan et al.
NEUROSCIENCE LETTERS (2010)
GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice
Gang Li et al.
CELL STEM CELL (2009)
Selective Effect of Age, Apo e4, and Alzheimer's Disease on Hippocampal Subfields
Susanne G. Mueller et al.
HIPPOCAMPUS (2009)
Automated 3D Mapping of Hippocampal Atrophy and Its Clinical Correlates in 400 Subjects with Alzheimer's Disease, Mild Cognitive Impairment, and Elderly Controls
Jonathan H. Morra et al.
HUMAN BRAIN MAPPING (2009)
Effects of Insulin and Octreotide on Memory and Growth Hormone in Alzheimer's Disease
G. Stennis Watson et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial
Samuel T. Henderson et al.
NUTRITION & METABOLISM (2009)
Distinct patterns of brain activity in young carriers of the APOE-ε4 allele
Nicola Filippini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Late-life anxiety and cognitive impairment: A review
Sherry A. Beaudreau et al.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2008)
Effect of ApoE genotype on response to donepezil in patients with Alzheimer's disease
Seong Hye Choi et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2008)
APOE genotype predicts depression in women with Alzheimer's disease: A retrospective study
Lisa Delano-Wood et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2008)
EEG alterations in non-demented individuals related to apolipoprotein E genotype and to risk of Alzheimer disease
N. V. Ponomareva et al.
NEUROBIOLOGY OF AGING (2008)
Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI
Clifford R. Jack et al.
NEUROBIOLOGY OF AGING (2008)
NSAID use and dementia risk in the cardiovascular health study - Role of APOE and NSAID type
C. A. Szekely et al.
NEUROLOGY (2008)
Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment
L. A. van de Pol et al.
NEUROLOGY (2007)
Apolipoprotein E polymorphism and dendritic shape in hippocampal interneurons
Baerbel Schoenheit et al.
NEUROBIOLOGY OF AGING (2007)
The role of higher-level cognitive function in gait: Executive dysfunction contributes to fall risk in Alzheimer's disease
Pamela L. Sheridan et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2007)
Relationship between the efficacy of rivastigmine and apolipoprotein E (ε4) in patients with mild to moderately severe Alzheimer disease
Rafael Blesa et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2006)
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
M. E. Risner et al.
PHARMACOGENOMICS JOURNAL (2006)
Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus
Qin Xu et al.
JOURNAL OF NEUROSCIENCE (2006)
Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype
MA Reger et al.
NEUROBIOLOGY OF AGING (2006)
Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: A multicentric electroencephalogram study
C Babiloni et al.
ANNALS OF NEUROLOGY (2006)
Effect of the apolipoprotein E epsilon 4 allele on the efficacy and tolerability of galantamine in the treatment of Alzheimer's disease
GH Suh et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2006)
Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity
SJ Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Executive function asymmetry in older adults genetically at-risk for Alzheimer's disease:: Verbal versus design fluency
WS Houston et al.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY (2005)
Modulation of apolipoprotein E structure by domain interaction - Differences in lipid-bound and lipid-free forms
DM Hatters et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism
EM Reiman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Sex, apolipoprotein E ε4 status, and hippocampal volume in mild cognitive impairment
A Fleisher et al.
ARCHIVES OF NEUROLOGY (2005)
The apolipoprotein E polymorphism is not associated with response to electroconvulsive therapy in major depressive disorder
M Huuhka et al.
JOURNAL OF ECT (2005)
Individual growth curve analysis of APOE ε4-associated cognitive decline in Alzheimer disease
BD Hoyt et al.
ARCHIVES OF NEUROLOGY (2005)
Role of tau protein in both physiological and pathological conditions
J Avila et al.
PHYSIOLOGICAL REVIEWS (2004)
Neuron-specific apolipoprotein E4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice
WJ Brecht et al.
JOURNAL OF NEUROSCIENCE (2004)
Increased anticholinergic challenge-induced memory impairment associated with the APOE-ε4 allele in the elderly:: A controlled pilot study
N Pomara et al.
NEUROPSYCHOPHARMACOLOGY (2004)
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
EM Reiman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
ApoE ε4 allele is associated with incidental hallucinations and delusions in patients with AD
JB Chang et al.
NEUROLOGY (2004)
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain
V Hirsch-Reinshagen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response
JR Lynch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
FM Harris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: interactions with apolipoprotein E genotype
S Craft et al.
PSYCHONEUROENDOCRINOLOGY (2003)
Neuropsychological deficits associated with Alzheimer's disease in the very-old:: Discrepancies in raw vs. standardized scores
MW Bondi et al.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY (2003)
Cognitive asymmetries associated with apolipoprotein E genotype in patients with Alzheimer's disease
MJ Finton et al.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY (2003)
Phosphorylation state of tau in the hippocampus of apolipoprotein E4 and E3 knock-in mice
M Kobayashi et al.
NEUROREPORT (2003)
Cerebral glucose metabolism, cerebrospinal fluid-β-amyloid1-42 (CSF-Aβ42), tau and apolipoprotein E genotype in long-term rivastigmine and tacrine treated Alzheimer disease (AD) patients
E Stefanova et al.
NEUROSCIENCE LETTERS (2003)
Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism
P Acharya et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2002)
Presence or absence of at least one ε4 allele and gender are not predictive for the response to donepezil treatment in Alzheimer's disease
AS Rigaud et al.
PHARMACOGENETICS (2002)
Progression of gait disorder and rigidity and risk of death in older persons
RS Wilson et al.
NEUROLOGY (2002)
Association between the APOE genotype and psychopathologic symptoms in Alzheimer's disease
N Scarmeas et al.
NEUROLOGY (2002)
Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurit eoutgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein
BP Nathan et al.
BRAIN RESEARCH (2002)
Apolipoprotein E and apolipoprotein E receptors modulate Aβ-induced glial neuroinflammatory responses
MJ LaDu et al.
NEUROCHEMISTRY INTERNATIONAL (2001)
Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
YD Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response
JR Lynch et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
Differences between GABA levels in Alzheimer's disease and Down syndrome with Alzheimer-like neuropathology
R Seidl et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2001)
Tacrine and rate of progression in Alzheimer's disease - relation to ApoE allele genotype
M Sjogren et al.
JOURNAL OF NEURAL TRANSMISSION (2001)
Responder characteristics to a single oral dose of cholinesterase inhibitor: A double-blind placebo-controlled study with tacrine in Alzheimer patients
O Almkvist et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2001)
Idiopathic senile gait disorders are signs of subclinical disease
BR Bloem et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2000)
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
J Lewis et al.
NATURE GENETICS (2000)
Galantamine in AD - A 6-month randomized, placebo-controlled trial with a 6-month extension
MA Raskind et al.
NEUROLOGY (2000)
The apolipoprotein E ε4 allele and the response to tacrine therapy in Alzheimer's disease
AS Rigaud et al.
EUROPEAN JOURNAL OF NEUROLOGY (2000)
Fall-related injuries in dementia with Lewy bodies (DLB) and Alzheimer's disease
T Imamura et al.
EUROPEAN JOURNAL OF NEUROLOGY (2000)
A longitudinal quantitative EEG study of Alzheimer's disease: Relation to apolipoprotein E polymorphism
M Lehtovirta et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2000)
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
I Tesseur et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
A pharmacogenomic approach to Alzheimer's disease
R Cacabelos et al.
ACTA NEUROLOGICA SCANDINAVICA (2000)