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Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease A Secondary Analysis of the Exenatide-PD Trial
Dilan Athauda et al.
JAMA NEUROLOGY (2019)
FDG-PET hypometabolism is more sensitive than MRI atrophy in Parkinson's disease: A whole-brain multimodal imaging meta-analysis
Franziska Albrecht et al.
NEUROIMAGE-CLINICAL (2019)
Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts
Hirotaka Iwaki et al.
NEUROLOGY-GENETICS (2019)
Assessment of a prognostic MRI biomarker in early de novo Parkinson's disease
Yashar Zeighami et al.
NEUROIMAGE-CLINICAL (2019)
Cerebellar resting-state functional connectivity in Parkinson's disease and multiple system atrophy: Characterization of abnormalities and potential for differential diagnosis at the single-patient level
Hugo C. Baggio et al.
NEUROIMAGE-CLINICAL (2019)
Reduced Activated T Lymphocytes (CD4+CD25+) and Plasma Levels of Cytokines in Parkinson's Disease
Natalia Pessoa Rocha et al.
MOLECULAR NEUROBIOLOGY (2018)
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology
Erik Portelius et al.
ACTA NEUROPATHOLOGICA (2018)
Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synucleinopathies
Ivan Martinez-Valbuena et al.
ACTA NEUROPATHOLOGICA (2018)
Substantia Nigra Free Water Increases Longitudinally in Parkinson Disease
T. Guttuso et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2018)
Serotonin, beta-amyloid, and cognition in Parkinson disease
Vikas Kotagal et al.
ANNALS OF NEUROLOGY (2018)
Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease
Xu Hou et al.
AUTOPHAGY (2018)
Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson's disease
Jonathan Schulz et al.
BRAIN (2018)
The genetic architecture of mitochondrial dysfunction in Parkinson's disease
S. B. Larsen et al.
CELL AND TISSUE RESEARCH (2018)
Interleukin-1 beta, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-alpha levels in CSF and serum in relation to the clinical diversity of Parkinson's disease
M. N. Karpenko et al.
CELLULAR IMMUNOLOGY (2018)
Increased serum levels of TNF-alpha and decreased serum levels of IL-27 in patients with Parkinson disease and their correlation with disease severity
Ebrahim Kouchaki et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2018)
Plasma Amyloid-beta (A beta(42)) Correlates with Cerebrospinal Fluid A beta(42) in Alzheimer's Disease
Charlotte E. Teunissen et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Interleukin 6 and complement serum level study in Parkinson's disease
Branislav Vesely et al.
JOURNAL OF NEURAL TRANSMISSION (2018)
Parkinson's disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+Th1/Th2/T17 and Treg in drug-naive and drugtreated patients
Natasa Kustrimovic et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort
Tanya Simuni et al.
MOVEMENT DISORDERS (2018)
Distinct Progression Pattern of Susceptibility MRI in the Substantia Nigra of Parkinson's Patients
Guangwei Du et al.
MOVEMENT DISORDERS (2018)
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
Chao Peng et al.
NATURE (2018)
Plasma alpha-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study
Hua Wang et al.
NEUROBIOLOGY OF DISEASE (2018)
Alpha-synuclein dimerization in erythrocytes of patients with genetic and non-genetic forms of Parkinson's Disease
Nikolaos Papagiannakis et al.
NEUROSCIENCE LETTERS (2018)
Expression of the DJ-1 protein in the serum of Chinese patients with Parkinson's disease
Chunna An et al.
NEUROSCIENCE LETTERS (2018)
Expression of the gene coading for PGC-1α in peripheral blood leukocytes and related gene variants in patients with Parkinson's disease
Xiao-Dong Yang et al.
PARKINSONISM & RELATED DISORDERS (2018)
A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation
Lorenzo Gaetani et al.
ALZHEIMERS RESEARCH & THERAPY (2018)
Plasma Biomarkers Differentiate Parkinson's Disease From Atypical Parkinsonism Syndromes
Chin-Hsien Lin et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
High Prevalence of Undiagnosed Insulin Resistance in Non-Diabetic Subjects with Parkinson's Disease
Elliot Hogg et al.
JOURNAL OF PARKINSONS DISEASE (2018)
α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity
Simona Daniele et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
Association Between Peripheral Inflammation and DATSCAN Data of the Striatal Nuclei in Different Motor Subtypes of Parkinson Disease
Hossein Sanjari Moghaddam et al.
FRONTIERS IN NEUROLOGY (2018)
Skin α-synuclein deposits differ in clinical variants of synucleinopathy: an in vivo study
V. Donadio et al.
SCIENTIFIC REPORTS (2018)
Reduced glucocerebrosidase activity in monocytes from patients with Parkinson's disease
Farzaneh Atashrazm et al.
SCIENTIFIC REPORTS (2018)
Peripheral blood inflammatory markers in early Parkinson's disease
Ryul Kim et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2018)
α-Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies
Inger van Steenoven et al.
MOVEMENT DISORDERS (2018)
Levels of plasma neurofilament light chain and cognitive function in patients with Alzheimer or Parkinson disease
Yung-Shuan Lin et al.
SCIENTIFIC REPORTS (2018)
Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease
Jens B. Schroeder et al.
FRONTIERS IN NEUROLOGY (2018)
Evaluation of the noradrenergic system in Parkinson's disease: an C-11-MeNER PET and neuromelanin MRI study
Michael Sommerauer et al.
BRAIN (2018)
Microglial activation in Parkinson's disease using [18F]-FEPPA
Christine Ghadery et al.
JOURNAL OF NEUROINFLAMMATION (2017)
CSF biomarkers β-amyloid, tau proteins and a-synuclein in the differential diagnosis of Parkinson-plus syndromes
Vasilios C. Constantinides et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2017)
Cerebrospinal Fluid β-Glucocerebrosidase Activity Is Reduced in Parkinson's Disease Patients
Lucilla Parnetti et al.
MOVEMENT DISORDERS (2017)
The Role of High-Field Magnetic Resonance Imaging in Parkinsonian Disorders: Pushing the Boundaries Forward
Stephane Lehericy et al.
MOVEMENT DISORDERS (2017)
Meta-Analysis of Dorsolateral Nigral Hyperintensity on Magnetic Resonance Imaging as a Marker for Parkinson's Disease
Philipp Mahlknecht et al.
MOVEMENT DISORDERS (2017)
Diagnostic Utility of Cerebrospinal Fluid α-Synuclein in Parkinson's Disease: A Systematic Review and Meta-Analysis
Paolo Eusebi et al.
MOVEMENT DISORDERS (2017)
Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease
Elijah Mak et al.
NEUROBIOLOGY OF AGING (2017)
Homovanillic acid in CSF of mild stage Parkinson's disease patients correlates with motor impairment
Alessandro Stefani et al.
NEUROCHEMISTRY INTERNATIONAL (2017)
Blood-based NfL A biomarker for differential diagnosis of parkinsonian disorder
Oskar Hansson et al.
NEUROLOGY (2017)
Evaluation of the Braak staging of brain pathology with 1H-MRS in patients with Parkinson's disease
Hongmei Cao et al.
NEUROSCIENCE LETTERS (2017)
Quantitative susceptibility mapping differentiates between parkinsonian disorders
Henrik Sjostrom et al.
PARKINSONISM & RELATED DISORDERS (2017)
Neurofilaments and Neurofilament Proteins in Health and Disease
Aidong Yuan et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Glucocerebrosidase Mutations in Parkinson Disease
Grace O'Regan et al.
JOURNAL OF PARKINSONS DISEASE (2017)
Detection and application of neurochemical profile by multiple regional 1H-MRS in Parkinson's disease
Jitian Guan et al.
BRAIN AND BEHAVIOR (2017)
Impaired synaptic function is linked to cognition in Parkinson's disease
Per Selnes et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2017)
Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers
Shijie Wang et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Synaptic proteins in CSF relate to Parkinson's disease stage markers
Erika Bereczki et al.
NPJ PARKINSONS DISEASE (2017)
Amyloid beta: structure, biology and structure-based therapeutic development
Guo-fang Chen et al.
ACTA PHARMACOLOGICA SINICA (2017)
Progression marker of Parkinson's disease: a 4-year multi-site imaging study
Roxana G. Burciu et al.
BRAIN (2017)
Insulin resistance and exendin-4 treatment for multiple system atrophy
Fares Bassil et al.
BRAIN (2017)
Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies
Anne Stuendl et al.
BRAIN (2016)
Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's
Ganqiang Liu et al.
ANNALS OF NEUROLOGY (2016)
Alpha-, Beta-, and Gamma-synuclein Quantification in Cerebrospinal Fluid by Multiple Reaction Monitoring Reveals Increased Concentrations in Alzheimer's and Creutzfeldt-Jakob Disease but No Alteration in Synucleinopathies
Patrick Oeckl et al.
MOLECULAR & CELLULAR PROTEOMICS (2016)
Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease
Nour K. Majbour et al.
MOLECULAR NEURODEGENERATION (2016)
Cerebrospinal Fluid Biomarkers in Alzheimer's and Parkinson's Diseases-From Pathophysiology to Clinical Practice
Kaj Blennow et al.
MOVEMENT DISORDERS (2016)
Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease
Kyle B. Fraser et al.
MOVEMENT DISORDERS (2016)
Motor and Nonmotor Features of Carriers of the p.A53T Alpha-Synuclein Mutation: A Longitudinal Study
Dimitra Papadimitriou et al.
MOVEMENT DISORDERS (2016)
Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD)
Caroline H. Williams-Gray et al.
MOVEMENT DISORDERS (2016)
Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression
Nour K. Majbour et al.
MOVEMENT DISORDERS (2016)
Levels of IL-8 and TNF-α decrease in Parkinson's disease
Vineeta Gupta et al.
NEUROLOGICAL RESEARCH (2016)
Stage-dependent loss of cortical gyrification as Parkinson disease unfolds
Nicholas W. Sterling et al.
NEUROLOGY (2016)
Functional MRI of disease progression in Parkinson disease and atypical parkinsonian syndromes
Roxana G. Burciu et al.
NEUROLOGY (2016)
Distinct brain networks underlie cognitive dysfunction in Parkinson and Alzheimer diseases
Paul J. Mattis et al.
NEUROLOGY (2016)
Increased CSF neurogranin concentration is specific to Alzheimer disease
Henrietta Wellington et al.
NEUROLOGY (2016)
A longitudinal study of neuromelanin-sensitive magnetic resonance imaging in Parkinson's disease
Keita Matsuura et al.
NEUROSCIENCE LETTERS (2016)
Scan without evidence of dopaminergic deficit: A 10-year retrospective study
Nicolas Nicastro et al.
PARKINSONISM & RELATED DISORDERS (2016)
Identification of a panel of five serum miRNAs as a biomarker for Parkinson's disease
Haixia Ding et al.
PARKINSONISM & RELATED DISORDERS (2016)
Magnetic Resonance Imaging Features of the Nigrostriatal System: Biomarkers of Parkinson's Disease Stages?
Lucie Hopes et al.
PLOS ONE (2016)
Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson's disease
Istvan Horvath et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Insulin resistance and Parkinson's disease: A new target for disease modification?
D. Athauda et al.
PROGRESS IN NEUROBIOLOGY (2016)
CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease
Julia Remnestal et al.
PROTEOMICS CLINICAL APPLICATIONS (2016)
How neuroinflammation contributes to neurodegeneration
Richard M. Ransohoff
SCIENCE (2016)
Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease A Systematic Review and Meta-analysis
Xiao-Yan Qin et al.
JAMA NEUROLOGY (2016)
Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease
Marie Y. Davis et al.
JAMA NEUROLOGY (2016)
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
Graham Fairfoul et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2016)
Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson's Disease
Giorgio Vivacqua et al.
PLOS ONE (2016)
Persistent Drug-Induced Parkinsonism in Patients with Normal Dopamine Transporter Imaging
Jin Yong Hong et al.
PLOS ONE (2016)
Diagnostic Accuracy of Transcranial Sonography of the Substantia Nigra in Parkinson's disease: A Systematic Review and Meta-analysis
Dun-Hui Li et al.
SCIENTIFIC REPORTS (2016)
Salivary total α-synuclein, oligomeric α-synuclein and SNCA variants in Parkinson's disease patients
Wenyan Kang et al.
SCIENTIFIC REPORTS (2016)
Cerebrospinal fluid neurogranin and YKL-40 as biomarkers of Alzheimer's disease
Shorena Janelidze et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2016)
Glucocerebrosidase activity in Parkinson's disease with and without GBA mutations
Roy N. Alcalay et al.
BRAIN (2015)
Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study
Elijah Mak et al.
BRAIN (2015)
(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation
Fabienne C. Fiesel et al.
EMBO REPORTS (2015)
Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling
Shanshan Gao et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)
A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes
N. K. Magdalinou et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2015)
Automated Neuromelanin Imaging as a Diagnostic Biomarker for Parkinson's Disease
Gabriel Castellanos et al.
MOVEMENT DISORDERS (2015)
Plasma amyloid β-quo vadis?
Henrik Zetterberg
NEUROBIOLOGY OF AGING (2015)
Increased free water in the substantia nigra of Parkinson's disease: a single-site and multi-site study
Edward Ofori et al.
NEUROBIOLOGY OF AGING (2015)
Detection of α-synuclein oligomers in red blood cells as a potential biomarker of Parkinson's disease
Xuemei Wang et al.
NEUROSCIENCE LETTERS (2015)
Neurodegenerative CSF markers in genetic and sporadic PD: Classification and prediction in a longitudinal study
Kathrin Brockmann et al.
PARKINSONISM & RELATED DISORDERS (2015)
Longitudinal midbrain changes in early Parkinson's disease: Iron content estimated from R2*/MRI
Marguerite Wieler et al.
PARKINSONISM & RELATED DISORDERS (2015)
The Inflammatory Marker YKL-40 Is Elevated in Cerebrospinal Fluid from Patients with Alzheimer's but Not Parkinson's Disease or Dementia with Lewy Bodies
Malin Wennstrom et al.
PLOS ONE (2015)
Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease
YaXing Gui et al.
ONCOTARGET (2015)
Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease
Lorraine V. Kalia et al.
JAMA NEUROLOGY (2015)
Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease
David C. Backstrom et al.
JAMA NEUROLOGY (2015)
Phosphorylated α-synuclein in Parkinson's disease: correlation depends on disease severity
Tessandra Stewart et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Susceptibility-Weighted Imaging Improves the Diagnostic Accuracy of 3T Brain MRI in the Work-Up of Parkinsonism
F. J. A. Meijer et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2015)
Mutual Exacerbation of Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Deregulation and α-Synuclein Oligomerization
Judith Eschbach et al.
ANNALS OF NEUROLOGY (2015)
Clinical evolution of Parkinson's disease and prognostic factors affecting motor progression: 9-year follow-up study
G. Reinoso et al.
EUROPEAN JOURNAL OF NEUROLOGY (2015)
Cerebrospinal fluid alpha-synuclein as a biomarker for Parkinson's disease diagnosis: a systematic review and meta-analysis
Liang Gao et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2015)
GBA-Associated Parkinson's Disease: Reduced Survival and More Rapid Progression in a Prospective Longitudinal Study
Kathrin Brockmann et al.
MOVEMENT DISORDERS (2015)
The increase of carcinoembryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophil/lymphocyte ratio in Parkinson's disease
Esref Akil et al.
NEUROLOGICAL SCIENCES (2015)
Baseline C-Reactive Protein Levels and Life Prognosis in Parkinson Disease
Hideyuki Sawada et al.
PLOS ONE (2015)
Identification of distinct circulating exosomes in Parkinson's disease
Paul R. Tomlinson et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)
Imaging Brain Iron and Diffusion Patterns: A Follow-up Study of Parkinson's Disease in the Initial Stages
Maija Elina Rossi et al.
ACADEMIC RADIOLOGY (2014)
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease
Min Shi et al.
ACTA NEUROPATHOLOGICA (2014)
Neuroimaging Biomarkers for Parkinson Disease: Facts and Fantasy
Joel S. Perlmutter et al.
ANNALS OF NEUROLOGY (2014)
Mild cognitive impairment is linked with faster rate of cortical thinning in patients with Parkinson's disease longitudinally
Alexandru Hanganu et al.
BRAIN (2014)
Progression of Brain Atrophy in the Early Stages of Parkinson's Disease: A Longitudinal Tensor-Based Morphometry Study in De Novo Patients Without Cognitive Impairment
Carlo Tessa et al.
HUMAN BRAIN MAPPING (2014)
Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction
Anna Mietelska-Porowska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial
Stephane Palfi et al.
LANCET (2014)
Imaging insights into basal ganglia function, Parkinson's disease, and dystonia
A. Jon Stoessl et al.
LANCET (2014)
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
Bruno Dubois et al.
LANCET NEUROLOGY (2014)
Cerebrospinal Fluid Lysosomal Enzymes and Alpha-Synuclein in Parkinson's Disease
Lucilla Parnetti et al.
MOVEMENT DISORDERS (2014)
Reduced Alpha-Synuclein in Cerebrospinal Fluid in Synucleinopathies: Evidence From a Meta-analysis
Wataru Sako et al.
MOVEMENT DISORDERS (2014)
CSF Aβ42 predicts early-onset dementia in Parkinson disease
Guido Alves et al.
NEUROLOGY (2014)
Functional connectivity in the basal ganglia network differentiates PD patients from controls
Konrad Szewczyk-Krolikowski et al.
NEUROLOGY (2014)
Astrocytic inclusions in progressive supranuclear palsy and corticobasal degeneration
Mari Yoshida
NEUROPATHOLOGY (2014)
Correlation between Serum RANTES Levels and the Severity of Parkinson's Disease
Peng Tang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Differentiation of early-stage parkinsonisms using neuromelanin-sensitive magnetic resonance imaging
Chigumi Ohtsuka et al.
PARKINSONISM & RELATED DISORDERS (2014)
CSF levels of DJ-1 and tau distinguish MSA patients from PD patients and controls
Megan K. Herbert et al.
PARKINSONISM & RELATED DISORDERS (2014)
Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to Alzheimer's disease
Oskar Hansson et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
Differential role of CSF alpha-synuclein species, tau, and Aβ42 in Parkinson's Disease
Lucilla Parnetti et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Measuring Disease Progression in Early Parkinson Disease The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience
Sotirios A. Parashos et al.
JAMA NEUROLOGY (2014)
May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum -Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?
Emilio Fernandez et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Glucocerebrosidase mutations influence the natural history of Parkinson's disease in a community-based incident cohort
Sophie E. Winder-Rhodes et al.
BRAIN (2013)
Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
Jing L. Guo et al.
CELL (2013)
The Topography of Brain Damage at Different Stages of Parkinson's Disease
Federica Agosta et al.
HUMAN BRAIN MAPPING (2013)
Levels of HVA, 5-HIAA, and MHPG in the CSF of vascular parkinsonism compared to Parkinson's disease and controls
Megan K. Herbert et al.
JOURNAL OF NEUROLOGY (2013)
Differentiation between idiopathic and atypical parkinsonian syndromes using three-dimensional magnetic resonance spectroscopic imaging
Adriane Groeger et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2013)
WHICH CLINICAL MEASURES ARE MOST APPROPRIATE FOR MEASURING DISEASE PROGRESSION IN PARKINSON'S DISEASE?
David McGhee et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2013)
The Glial Marker YKL-40 Is Decreased in Synucleinopathies
Bob Olsson et al.
MOVEMENT DISORDERS (2013)
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
David J. Irwin et al.
NATURE REVIEWS NEUROSCIENCE (2013)
α-Synuclein in cutaneous autonomic nerves
Ningshan Wang et al.
NEUROLOGY (2013)
Differential diagnosis of parkinsonian syndromes using F-18 fluorodeoxyglucose positron emission tomography
Madhavi Tripathi et al.
NEURORADIOLOGY (2013)
Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects
Brit Mollenhauer et al.
NEUROSCIENCE LETTERS (2013)
Diabetes is associated with postural instability and gait difficulty in Parkinson disease
Vikas Kotagal et al.
PARKINSONISM & RELATED DISORDERS (2013)
Is R2* a New MRI Biomarker for the Progression of Parkinson's Disease? A Longitudinal Follow-Up
Miguel Ulla et al.
PLOS ONE (2013)
Plasma Ceramide and Glucosylceramide Metabolism Is Altered in Sporadic Parkinson's Disease and Associated with Cognitive Impairment: A Pilot Study
Michelle M. Mielke et al.
PLOS ONE (2013)
Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study
Jeffrey Randall et al.
RESUSCITATION (2013)
A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease
Penelope G. Foulds et al.
SCIENTIFIC REPORTS (2013)
Diffusion tensor imaging of nigral degeneration in Parkinson's disease: A region-of-interest and voxel-based study at 3T and systematic review with meta-analysis
Stefan T. Schwarz et al.
NEUROIMAGE-CLINICAL (2013)
α-synuclein Imaging: A Critical Need for Parkinson's Disease Research
Jamie L. Eberling et al.
JOURNAL OF PARKINSONS DISEASE (2013)
Metabolic brain networks in translational neurology: Concepts and applications
Martin Niethammer et al.
ANNALS OF NEUROLOGY (2012)
Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders
Sara Hall et al.
ARCHIVES OF NEUROLOGY (2012)
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
David J. Irwin et al.
BRAIN (2012)
Resting state functional connectivity of the striatum in Parkinson's disease
Carl D. Hacker et al.
BRAIN (2012)
Correlational study of the serum levels of the glial fibrillary acidic protein and neurofilament proteins in Parkinson's disease patients
Wen Su et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2012)
Patient Diaries As a Clinical Endpoint in Parkinson's Disease Clinical Trials
Spyridon (Spyros) Papapetropoulos
CNS NEUROSCIENCE & THERAPEUTICS (2012)
Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [18F]-FEPPA
Romina Mizrahi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
CD4+Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson's Disease
Jessica A. Hutter Saunders et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)
Comparison of patient rated treatment response with measured improvement in Parkinson's disease
Matthew B. Davidson et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2012)
Dementia is associated with Insulin Resistance in patients with Parkinson's Disease
Domenico Bosco et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2012)
Imaging nigral pathology and clinical progression in Parkinson's disease
Guangwei Du et al.
MOVEMENT DISORDERS (2012)
Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies
P. G. Foulds et al.
NEUROBIOLOGY OF DISEASE (2012)
The DJ-1 concentration in cerebrospinal fluid does not differentiate among parkinsonian syndromes
Lisette Salvesen et al.
PARKINSONISM & RELATED DISORDERS (2012)
Metabolite Profiling of Alzheimer's Disease Cerebrospinal Fluid
Christian Czech et al.
PLOS ONE (2012)
Non-Motor Symptoms in Patients with Parkinson's Disease - Correlations with Inflammatory Cytokines in Serum
Daniel Lindqvist et al.
PLOS ONE (2012)
Phosphorylated α-Synuclein in Parkinson's Disease
Yu Wang et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
Oliver Cooper et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease
Ivana Devic et al.
BRAIN (2011)
Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease
Ramachandiran Nandhagopal et al.
BRAIN (2011)
CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease
Peter LeWitt et al.
BRAIN RESEARCH (2011)
Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease
Penelope G. Foulds et al.
FASEB JOURNAL (2011)
Elevated Levels of α-Synuclein Oligomer in the Cerebrospinal Fluid of Drug-Naive Patients with Parkinson's Disease
Min Jeong Park et al.
JOURNAL OF CLINICAL NEUROLOGY (2011)
Diffusion tensor imaging and olfactory identification testing in early-stage Parkinson's disease
Tyler M. Rolheiser et al.
JOURNAL OF NEUROLOGY (2011)
Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease
Syed Z. Imam et al.
JOURNAL OF NEUROSCIENCE (2011)
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study (vol 10, pg 230, 2011)
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LANCET NEUROLOGY (2011)
Cerebrospinal Fluid Tau and Phosphorylated Tau Protein are Elevated in Corticobasal Syndrome
M. B. Aerts et al.
MOVEMENT DISORDERS (2011)
α-Synuclein Reactive Antibodies as Diagnostic Biomarkers in Blood Sera of Parkinson's Disease Patients
Kiran Yanamandra et al.
PLOS ONE (2011)
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
Brit Mollenhauer et al.
LANCET NEUROLOGY (2011)
CSF and plasma concentrations of free norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC), 3,4-dihydroxyphenylalanine (DOPA), and epinephrine in Parkinson's disease.
E. Eldrup et al.
ACTA NEUROLOGICA SCANDINAVICA (2010)
Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
Thomas G. Beach et al.
ACTA NEUROPATHOLOGICA (2010)
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
Zhen Hong et al.
BRAIN (2010)
Synergistic Interactions between Aβ, Tau, and α-Synuclein: Acceleration of Neuropathology and Cognitive Decline
Lani K. Clinton et al.
JOURNAL OF NEUROSCIENCE (2010)
Differential diagnosis of parkinsonism: a metabolic imaging study using pattern analysis
Chris C. Tang et al.
LANCET NEUROLOGY (2010)
Plasma α-Synuclein in Patients with Parkinson's Disease With and Without Treatment
Raquel Duran et al.
MOVEMENT DISORDERS (2010)
Staging of serotonergic dysfunction in Parkinson's Disease: An in vivo 11C-DASB PET study
Marios Politis et al.
NEUROBIOLOGY OF DISEASE (2010)
Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease
T. Tokuda et al.
NEUROLOGY (2010)
CSF amyloid β 1-42 predicts cognitive decline in Parkinson disease
A. Siderowf et al.
NEUROLOGY (2010)
Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease
Min Shi et al.
NEUROSCIENCE LETTERS (2010)
Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease
Elke Hattingen et al.
BRAIN (2009)
DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders
Philipp J. Kahle et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
A Follow-Up Study on 6-[18F]Fluoro-L-dopa Uptake in Early Parkinson's Disease Shows Nonlinear Progression in the Putamen
Anna Bruck et al.
MOVEMENT DISORDERS (2009)
Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET
H. Shimada et al.
NEUROLOGY (2009)
High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease
D. E. Vaillancourt et al.
NEUROLOGY (2009)
Serum inflammatory biomarkers in Parkinson's disease
M. Dufek et al.
PARKINSONISM & RELATED DISORDERS (2009)
Metabolic brain networks in neurodegenerative disorders: a functional imaging approach
David Eidelberg
TRENDS IN NEUROSCIENCES (2009)
Cathepsin D is the main lysosomal enzyme involved in the degradation of α-synuclein and generation of its carboxy-terminally truncated species
Daniel Sevlever et al.
BIOCHEMISTRY (2008)
Cerebrospinal Fluid Biomarkers in Parkinson's Disease with Dementia and Dementia with Lewy Bodies
Lucilla Parnetti et al.
BIOLOGICAL PSYCHIATRY (2008)
Lewy body pathology involves cutaneous nerves
Masako Ikemura et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
The specificity and sensitivity of transcranial ultrasound in the differential diagnosis of Parkinson's disease: a prospective blinded study
Alexandra Gaenslen et al.
LANCET NEUROLOGY (2008)
Secretion of DJ-1 into the serum of patients with Parkinson's disease
Chinatsu Maita et al.
NEUROSCIENCE LETTERS (2008)
Circulating interleukin-15 and RANTES chemokine in Parkinson's disease
M. Rentzos et al.
ACTA NEUROLOGICA SCANDINAVICA (2007)
Plasma levels of DJ-1 as a possible marker for progression of sporadic Parkinson's disease
Masaaki Waragai et al.
NEUROSCIENCE LETTERS (2007)
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
Frederic Tremblay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Enhanced accumulation of phosphorylated α-synuclein in double transgenic mice expressing mutant β-amyloid precursor protein and presenilin-1
Tomoko Kurata et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
Changes in network activity with the progression of Parkinson's disease
Chaorui Huang et al.
BRAIN (2007)
Magnetic resonance spectroscopic evidence for pre supplementary motor area neuronal dysfunction in Parkinson's disease
Richard M. Camicioli et al.
MOVEMENT DISORDERS (2007)
Metabolic brain networks associated with cognitive function in Parkinson's disease
Chaorui Huang et al.
NEUROIMAGE (2007)
Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
Takahiko Tokuda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Network modulation in the treatment of Parkinson's disease
Kotaro Asanuma et al.
BRAIN (2006)
Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease
Masaaki Waragai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Transcranial sonography and [123I]FP-CIT SPECT disclose complementary aspects of Parkinson's disease
J Spiegel et al.
BRAIN (2006)
Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
Omar M. A. El-Agnaf et al.
FASEB JOURNAL (2006)
Presenilin clinical mutations can affect γ-secretase activity by different mechanisms
M Bentahir et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia
N Pankratz et al.
MOVEMENT DISORDERS (2006)
FDG PET in the differential diagnosis of parkinsonian disorders
T Eckert et al.
NEUROIMAGE (2005)
Five-year follow-up study of hyperechogenicity of the substantia nigra in Parkinson's disease
D Berg et al.
MOVEMENT DISORDERS (2005)
Microglial activation and dopamine terminal loss in early Parkinson's disease
Y Ouchi et al.
ANNALS OF NEUROLOGY (2005)
Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls
EJ Burton et al.
BRAIN (2004)
A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease
MJ Firbank et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2002)
Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease
KA Jellinger et al.
JOURNAL OF NEURAL TRANSMISSION (2002)
β-synuclein inhibits α-synuclein aggregation:: A possible role as an anti-parkinsonian factor
M Hashimoto et al.
NEURON (2001)
Echogenicity of the substantia nigra in Parkinsons disease and its relation to clinical findings
D Berg et al.
JOURNAL OF NEUROLOGY (2001)
Cortical dysfunction in non-demented Parkinson's disease patients -: A combined 31P-MRS and 18FDG-PET study
MTM Hu et al.
BRAIN (2000)
CSF levels of tau, beta-amyloid(1-42) and GAP-43 in frontotemporal dementia, other types of dementia and normal aging
M Sjogren et al.
JOURNAL OF NEURAL TRANSMISSION (2000)