☆ 4.6 Article

Exploring Co-occurrence patterns and microbial diversity in the lung microbiome of patients with non-small cell lung cancer

BMC MICROBIOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Oncology

The airway microbiota of non-small cell lung cancer patients and its relationship to tumor stage and EGFR gene mutation

Dan Hui Huang et al.

Summary: This study found differences in the taxonomy structure of sputum microbiota in different stages of lung cancer. Tumor stage, intrathoracic metastasis, lymph node metastasis, and EGFR mutation were associated with altered specific airway genera and metabolic function of sputum microbiota.

THORACIC CANCER (2022)

添加到收藏夹

Article Microbiology

Altered Ecology of the Respiratory Tract Microbiome and Nosocomial Pneumonia

Ana Elena Perez-Cobas et al.

Summary: Nosocomial pneumonia is a common infection in critical patients, primarily associated with mechanical ventilation. The rise in multidrug-resistant bacterial infections has increased mortality rates, posing a global public health threat. Recent research suggests that a healthy respiratory tract microbiome (RTM) stimulates the immune system and protects against pathogen infection. However, the physiological conditions and interventions in critical patients disrupt the RTM, leading to dysbiosis. The significance of host-RTM interactions in nosocomial infections remains mostly unknown.

FRONTIERS IN MICROBIOLOGY (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Convergent alteration of lung tissue microbiota and tumor cells in lung cancer

Hui Dong et al.

Summary: The study found that lung tumor microbiota from smokers contained more PAH-degrading microbes, and TP53 mutation was more prevalent in smokers. Further analysis showed that there was consistency between the changes in the microbiota of smokers and tumor cells, and TP53-mutated tumor microbiota exhibited dysregulation of the p53 signaling pathway.

ISCIENCE (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Alterations of lung microbiota in patients with non-small cell lung cancer

Wen Zeng et al.

Summary: This study found that lung microbiota in patients with non-small cell lung cancer differed significantly from those with benign lung disease, with the genera Prevotella and Veillonella being the most strongly associated with non-small cell lung cancer. Veillonella was also found to significantly promote the progression of lung cancer in vivo. Metabolic prediction revealed enrichment of certain pathways that may be involved in the progression of non-small cell lung cancer. These findings suggest that the composition and function of lung microbiota undergo significant changes during the progression of non-small cell lung cancer, and these differing genera may have potential as diagnostic markers and therapeutic targets.

BIOENGINEERED (2022)

添加到收藏夹

Article Oncology

The Oral Microbiome and Lung Cancer Risk: An Analysis of 3 Prospective Cohort Studies

Emily Vogtmann et al.

Summary: This study found prospective associations between oral microbiota and lung cancer risk in 3 US cohort studies, with variations based on smoking history and histological subtype.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2022)

添加到收藏夹

Article Biology

Sputum Microbiome Composition in Patients with Squamous Cell Lung Carcinoma

Elizaveta Baranova et al.

Summary: This study compared the taxonomic composition of the sputum microbiome between untreated LUSC patients and healthy controls. The results showed significant differences in the structure of bacterial communities between the two groups. Certain genera were found to be enriched in LUSC patients, while others were significantly reduced, indicating a decrease in beta diversity in the microbiome of LUSC patients.

LIFE-BASEL (2022)

添加到收藏夹

Review Microbiology

The composition of lung microbiome in lung cancer: a systematic review and meta-analysis

Sadaf Najafi et al.

Summary: The study found that several bacterial taxa, including Actinobacteria phylum, Corynebacteriaceae and Halomonadaceae families, and Corynebacterium, Lachnoanaerobaculum, and Halomonas genera, were significantly decreased in lung tumor tissues of lung cancer patients compared to tumor-adjacent normal tissues. Despite the need for further scrutiny, this study establishes a foundation for future research and enhances our understanding of the lung microbiome's role in lung cancer. More data on demographic factors and tumor tissue types would improve accuracy in characterizing the lung microbial community in different stages of the disease and fully capturing changes in the lung microbiome in lung cancer.

BMC MICROBIOLOGY (2021)

添加到收藏夹

Article Genetics & Heredity

Genetic damage in lymphocytes of lung cancer patients is correlated to the composition of the respiratory tract microbiome

V. G. Druzhinin et al.

Summary: Recent findings suggest that the microbiome may play a significant role in the development of lung cancer by affecting inflammation, dysbiosis, and genome damage. A study comparing the sputum microbiome of untreated lung cancer (LC) patients with chromosomal aberrations and micronuclei in peripheral blood lymphocytes showed higher frequencies in the LC group. Specific bacterial genera were associated with genome damage markers in LC patients. The study supports previous research suggesting a link between the airway microbiome and lung cancer.

MUTAGENESIS (2021)

添加到收藏夹

Article Microbiology

Alterations of the Human Lung and Gut Microbiomes in Non-Small Cell Lung Carcinomas and Distant Metastasis

Hui Lu et al.

Summary: The study revealed significant disturbances in both gut and sputum microbiota in non-small cell lung cancer (NSCLC) patients, with the sputum microbiota being associated with distant metastasis (DM). Mathematical models utilizing both microbiotas showed better performance in patient stratification, while sputum models performed similarly to combined models, suggesting a potential noninvasive diagnostic method for NSCLC. Shared microbial biomarkers across different disease stages indicate the underlying progression of the disease, with signals for distant metastasis potentially detectable at early stages.

MICROBIOLOGY SPECTRUM (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Non-small cell lung cancer microbiota characterization: Prevalence of enteric and potentially pathogenic bacteria in cancer tissues

Nathan Dumont-Leblond et al.

Summary: This study characterized the microbiota in lung cancer tissues of 29 non-small cell cancer patients, revealing unique bacterial signatures for each patient and a higher frequency of enteric, potentially pathogenic, and pro-inflammatory bacteria in cancer tissues compared to healthy tissues.

PLOS ONE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Reductive evolution and unique predatory mode in the CPR bacterium Vampirococcus lugosii

David Moreira et al.

Summary: The Candidate Phyla Radiation (CPR) is a large group of bacterial lineages with small cell sizes and limited biosynthetic capabilities, where parasitism is a common lifestyle. The study of Vampirococcus lugosii, an epibiotic parasite of other bacteria, revealed that it feeds on anoxygenic photosynthetic gammaproteobacteria, divides epibiotically, and has a genome reduced in biosynthetic metabolism genes but enriched in genes possibly involved in interactions with the host.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Biology

NFnetFu: A novel workflow for microbiome data fusion

Vartika Bisht et al.

Summary: Microbiome data analysis faces challenges such as collinearity, sparsity, and effect size, with the need for interpretable models integrating data and background knowledge. A multimodal framework has been developed to address these challenges and provide candidate taxa/OTUs for future validation experiments.

COMPUTERS IN BIOLOGY AND MEDICINE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

Deborah Nejman et al.

SCIENCE (2020)

添加到收藏夹

Article Oncology

Characterization of Microbiota in Cancerous Lung and the Contralateral Non-Cancerous Lung Within Lung Cancer Patients

Minglei Zhuo et al.

FRONTIERS IN ONCOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Lung Microbiome Differentially Impacts Survival of Patients with Non-Small Cell Lung Cancer Depending on Tumor Stroma Phenotype

Olga Kovaleva et al.

BIOMEDICINES (2020)

添加到收藏夹

Letter Biotechnology & Applied Microbiology

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

Evan Bolyen et al.

NATURE BIOTECHNOLOGY (2019)

添加到收藏夹

Article Oncology

Whole genome sequencing revealed microbiome in lung adenocarcinomas presented as ground-glass nodules

Yijiu Ren et al.

TRANSLATIONAL LUNG CANCER RESEARCH (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Targeted isolation and cultivation of uncultivated bacteria by reverse genomics

Karissa L. Cross et al.

NATURE BIOTECHNOLOGY (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Microbiome networks and change-point analysis reveal key community changes associated with cystic fibrosis pulmonary exacerbations

Mehdi Layeghifard et al.

NPJ BIOFILMS AND MICROBIOMES (2019)

添加到收藏夹

Article Respiratory System

Community analysis and co-occurrence patterns in airway microbial communities during health and disease

Gisli G. Einarsson et al.

ERJ OPEN RESEARCH (2019)

添加到收藏夹

Article Oncology

Salivary Microbial Dysbiosis is Associated with Systemic Inflammatory Markers and Predicted Oral Metabolites in Non-Small Cell Lung Cancer Patients

Weiquan Zhang et al.

JOURNAL OF CANCER (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Characterization of the duodenal bacterial microbiota in patients with pancreatic head cancer vs. healthy controls

Qi-Xiang Mei et al.

PANCREATOLOGY (2018)

添加到收藏夹

Article Microbiology

PARP1 Is Up-Regulated in Non-small Cell Lung Cancer Tissues in the Presence of the Cyanobacterial Toxin Microcystin

Patrick L. Apopa et al.

FRONTIERS IN MICROBIOLOGY (2018)

添加到收藏夹

Article Medicine, General & Internal

Characterisation of gut, lung, and upper airways microbiota in patients with non-small cell lung carcinoma Study protocol for case-control observational trial

Rea Bingula et al.

MEDICINE (2018)

添加到收藏夹

Article Ecology

Exact sequence variants should replace operational taxonomic units in marker-gene data analysis

Benjamin J. Callahan et al.

ISME JOURNAL (2017)

添加到收藏夹

Article Multidisciplinary Sciences

A pilot study using metagenomic sequencing of the sputum microbiome suggests potential bacterial biomarkers for lung cancer

Simon J. S. Cameron et al.

PLOS ONE (2017)

添加到收藏夹

Article Oncology

Characterization of microbiome in bronchoalveolar lavage fluid of patients with lung cancer comparing with benign mass like lesions

Sang Hoon Lee et al.

LUNG CANCER (2016)

添加到收藏夹

Article Biochemical Research Methods

DADA2: High-resolution sample inference from Illumina amplicon data

Benjamin J. Callahan et al.

NATURE METHODS (2016)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical features

Guoqin Yu et al.

GENOME BIOLOGY (2016)

添加到收藏夹

Review Toxicology

The transient but not resident (TBNR) microbiome: a Yin Yang model for lung immune system

Pardis Saeedi et al.

INHALATION TOXICOLOGY (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle

Xuesong He et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

添加到收藏夹

Article Ecology

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

Daniel McDonald et al.

ISME JOURNAL (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease

Sharon Greenblum et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

添加到收藏夹

Article Allergy

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

Yvonne J. Huang et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.