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Article
Geriatrics & Gerontology
Clarissa Giebel et al.
Summary: This study investigates the impact of vaccination uptake and testing on care home visitation. Findings reveal delayed and inconsistent offers of face-to-face visits, varying uptake of the COVID-19 vaccine, and lack of education leading to different perspectives and frustrations among family carers and care home staff.
Article
Public, Environmental & Occupational Health
Stephanie M. Toth-Manikowski et al.
Summary: The survey revealed that most healthcare workers are willing to receive the COVID-19 vaccine, but a significant number remain hesitant. Factors such as race, political affiliation, and allergies were found to affect healthcare workers' decision on vaccination. Efforts to improve communication and support from colleagues may help increase vaccination rates among healthcare workers.
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Letter
Public, Environmental & Occupational Health
Mark McConaghy et al.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Immunology
Erica Jane Cook et al.
Summary: Despite being at higher risk of COVID-19 and experiencing poorer health outcomes, the minority ethnic population in the UK has lower uptake of the COVID-19 vaccine compared with their white British counterparts. This research investigates the influential factors that impact the decision to accept the COVID-19 vaccination among an ethnically diverse community in Luton, UK. The findings highlight the importance of age, ethnicity, and knowledge as influential factors in predicting vaccine hesitancy, and suggest that lack of trust in government/authorities and concerns about the speed of vaccine development are common reasons for non-uptake.
Article
Public, Environmental & Occupational Health
O. Williams et al.
Summary: This study examines the epidemiology of COVID-19 outbreaks in four care homes in Wales, revealing widespread transmission and high mortality rates. Universal testing and early isolation of residents are recommended.
JOURNAL OF PUBLIC HEALTH
(2022)
Review
Multidisciplinary Sciences
Debendra Nath Roy et al.
Summary: This study systematically examined potential factors influencing COVID-19 vaccine acceptance and refusal intention, revealing common but also varying important considerations across countries.
Article
Medicine, General & Internal
Amelia Dennis et al.
Summary: Barriers and mistrust exist among care home employees in receiving the COVID-19 vaccine, and most employees do not support vaccination as a condition of deployment.
Article
Immunology
Charlene Hl Wong et al.
Summary: This study aimed to identify barriers and facilitators to COVID-19 vaccine uptake in Hong Kong and develop implementation strategies based on theoretical frameworks. The findings identified several barriers, such as concerns about side effects and a lack of confidence in safety and effectiveness, as well as facilitators, including recommendations from healthcare professionals and trusted information sources. Based on these findings, seven implementation strategies were developed, including providing trustworthy information, incentivizing vaccinations, and increasing accessibility.
Article
Immunology
Jordan Yeo et al.
Summary: This study aims to understand the perspectives of vaccine-hesitant caregivers in order to provide targeted recommendations for healthcare workers and policymakers to engage in more effective vaccine discussions. Through telephone interviews and thematic analysis, barriers and facilitators of COVID-19 immunization were identified, and strategies such as education, trust-building, and societal pressure were suggested to increase vaccine uptake in children.
Article
Health Care Sciences & Services
Anna Schultze et al.
Summary: The mortality risk among care home residents in England was significantly higher compared to older residents of private homes during the first wave of the COVID-19 pandemic. However, this disproportionate impact was not observed in the second wave, indicating potential factors such as acquired immunity, improved protective measures, or changes in population frailty. Prioritizing measures aimed at controlling COVID-19 for the care home population is recommended based on the findings.
LANCET REGIONAL HEALTH-EUROPE
(2022)
Article
Geriatrics & Gerontology
Massimo Micocci et al.
Summary: This study identified four main steps in testing pathways in care homes, including infection prevention, preparation, swabbing, and resident management. Swabbing was resource-intensive and challenging for mobile residents with cognitive impairment. Many care homes reported deviating from government guidance to take more cautious approaches in managing post-test situations.
Article
Medicine, General & Internal
Thomas F. D. Mason et al.
Summary: The study aimed to estimate the effectiveness of the BNT162b2 mRNA vaccine in older adults in England and found that vaccination significantly reduced hospitalization and infection rates of COVID-19.
Article
Geriatrics & Gerontology
Kathleen T. Unroe et al.
Summary: A survey conducted by the Indiana Department of Health among nursing home and assisted living facility staff revealed that 45% of respondents were willing to receive the approved COVID-19 vaccine immediately, with concerns about side effects being the primary reason for hesitancy. Overall, willingness to receive the vaccine could be as high as 69%, but varied among different subgroups of nursing home staff. Strengthening education on the vaccine for staff may be critical in increasing uptake.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Multidisciplinary Sciences
Jamie Murphy et al.
Summary: Identifying and understanding COVID-19 vaccine hesitancy within distinct populations may aid future public health messaging. Using nationally representative data from the general adult populations of Ireland and the UK, the study found differences in vaccine hesitancy/resistance between the two countries but similarities in psychological constructs among resistant respondents. Vaccine-resistant individuals in both populations were less likely to obtain information from traditional and authoritative sources and had similar levels of mistrust in these sources compared to vaccine-accepting individuals.
NATURE COMMUNICATIONS
(2021)
Article
Biotechnology & Applied Microbiology
Susan M. Sherman et al.
Summary: Most UK adults have a positive attitude towards being vaccinated against COVID-19, with factors such as general vaccine beliefs and attitudes, information sufficiency, and risk perception influencing vaccination intention. Intention to be vaccinated may be influenced by factors such as vaccine safety, perception of COVID-19 risk, among others.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Medicine, General & Internal
Marcello Morciano et al.
Summary: By August 7, 2020, there were 29,542 (95% CI 25,176 to 33,908) excess deaths in all care homes in England. Excess deaths accounted for 6.5% (95% CI 5.5 to 7.4%) of all care home beds, with a higher rate in nursing homes (8.4%) compared to residential homes (4.6%). 64.7% (95% CI 56.4 to 76.0%) of excess deaths were confirmed/suspected COVID-19 cases. The odds of experiencing COVID-19 attributable deaths were higher in homes providing nursing services, with older residents and/or dementia patients, larger homes, and belonging to a large provider/brand, but not significantly associated with for-profit status.
Article
Public, Environmental & Occupational Health
Konstantinos Daras et al.
Summary: The study found that in England, factors such as ethnicity, poverty, long-term health problems, living in care homes, and overcrowded housing were associated with COVID-19 mortality rates. Different vulnerable groups are unevenly distributed in different communities, and high levels of vulnerability in certain communities indicate increased risk for a second wave of the pandemic.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2021)
News Item
Medicine, General & Internal
Owen Dyer
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Louis Goffe et al.
Summary: The study found that factors positively associated with COVID-19 vaccine intentions included favorable vaccine views, trust in institutions associated with vaccine approval, anticipated regret of not having a vaccine, perceived vaccine benefits, and history of having an influenza vaccine. On the other hand, factors negatively associated were anti-lockdown views and being a health or social care worker. Ethnicity and neighborhood deprivation also showed independent relationships with intention.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Geriatrics & Gerontology
Jennifer K. Burton et al.
Summary: This study quantified the mortality burden of COVID-19 on care-home residents and found it to be common. Results showed that COVID-19 infection has led to the loss of substantial years of life in care-home residents aged 70 years and over in Scotland. Prioritizing vaccination for care-home residents aged 70 and over is justified not only in terms of total deaths, but also in terms of years of life lost.
Review
Public, Environmental & Occupational Health
Eve Dube et al.
Summary: Despite the clear benefits of vaccination that are widely acknowledged by the scientific and medical community, an increasing number of people are perceiving vaccines as unsafe and unnecessary. Refusal or hesitancy to vaccinate is identified as one of the ten threats to global health in 2019, with the negative influence of anti-vaccination movements being named as a cause of increasing vaccine resistance in the public.
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 42, 2021
(2021)
Article
Immunology
Linda Craig et al.
Summary: This study explored the implementation and uptake of the COVID-19 vaccination programme in care homes in Northern Ireland from the perspective of care home managers. Factors motivating residents and staff to receive the vaccine were identified, as well as challenges to vaccine uptake. The findings stressed the crucial role of managers in building trust and relationships to address these challenges.
Review
Immunology
Atiya Kamal et al.
Summary: Minority ethnic groups in the UK face higher vaccine hesitancy and lower uptake rates compared to White British groups, with barriers such as mistrust in formal services, lack of safety information about vaccines, and misinformation. Facilitators include inclusive communication addressing vaccine concerns through trusted sources and increased visibility of minority ethnic groups in the media. Community engagement utilizing trusted and collaborative networks is essential to address concerns and informational needs, likely leading to increased vaccine equity and uptake.
Editorial Material
Medicine, General & Internal
Mishal S. Khan et al.
Editorial Material
Biochemistry & Molecular Biology
Susan Michie et al.
Summary: Collaboration among behavioral, social, biomedical, public-health, and clinical scientists is necessary to address the continuing threat from COVID-19 and future pandemics through investment in research and programs to discover and apply the principles that underpin sustained behavior change.
Article
Multidisciplinary Sciences
Daniel Graeber et al.
Summary: In Germany, 70% of adults are willing to get vaccinated against COVID-19, with half in support of a mandatory vaccination policy and half against it. The willingness to get vaccinated positively correlates with acceptance of mandatory vaccination policy, and individual characteristics significantly impact vaccination intentions and policy acceptance.
Review
Public, Environmental & Occupational Health
Qiang Wang et al.
Summary: The study estimated a COVID-19 vaccine acceptance rate of 73.31%, with the general population showing higher acceptance than healthcare workers. Factors such as history of influenza vaccination, educational level, gender, and trust in the government were strong predictors of willingness to accept the COVID-19 vaccine.
PREVENTIVE MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
James M. Burke et al.
Summary: The study found that during SARS-CoV-2 infection, the biogenesis of IFN mRNAs is inhibited at multiple steps, including limited translocation of transcription factor IRF3 to the nucleus, localization of IFN mRNAs primarily at the site of transcription in most infected cells, and inhibition of nuclear-cytoplasmic transport. These results suggest that SARS-CoV-2 weakens the transcriptional induction of IFN genes through multiple mechanisms, inhibiting the production of interferon proteins in host cells and affecting the antiviral immune response.
Review
Health Policy & Services
Nirbachita Biswas et al.
Summary: COVID-19 vaccines have been approved for public use globally, but studies show healthcare workers globally exhibit vaccine hesitancy due to concerns about safety, efficacy, and side effects. Males, older individuals, and those with doctoral degrees (i.e., physicians) are more likely to accept vaccines, and factors like perceived risk, patient care involvement, and influenza vaccination history increase vaccine uptake likelihood. Strategies to improve communication, education, and mandates for clinical workers are crucial to address the high prevalence of vaccine hesitancy in healthcare workers. Healthcare workers play a key role in pandemic mitigation, serving as role models for preventive behaviors and facilitating vaccination efforts.
JOURNAL OF COMMUNITY HEALTH
(2021)
Article
Immunology
Tiffany W. Y. Ng et al.
Article
Medicine, General & Internal
Temet M. McMichael et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2020)
Editorial Material
Public, Environmental & Occupational Health
Dheepa Rajan et al.
Article
Infectious Diseases
Shamez N. Ladhani et al.
JOURNAL OF INFECTION
(2020)
Review
Medicine, General & Internal
Michael Richard Perkin et al.
Article
Environmental Sciences
Eidin Ni She et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Psychology, Clinical
Lynn Williams et al.
BRITISH JOURNAL OF HEALTH PSYCHOLOGY
(2020)
Article
Health Care Sciences & Services
Lou Atkins et al.
IMPLEMENTATION SCIENCE
(2017)
Article
Health Care Sciences & Services
Frank Davidoff et al.
BMJ QUALITY & SAFETY
(2015)
Article
Health Care Sciences & Services
Susan Michie
BMC HEALTH SERVICES RESEARCH
(2014)
Article
Psychology, Multidisciplinary
Susan Michie et al.
ANNALS OF BEHAVIORAL MEDICINE
(2013)
Article
Health Care Sciences & Services
Susan Michie et al.
IMPLEMENTATION SCIENCE
(2011)
