期刊
BIORESOURCE TECHNOLOGY
卷 379, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2023.129045
关键词
Lignin; Ligninase; Metabolomics; Lignocellulosic biomass; Metabolic pathway engineering
This review focuses on the research progress of lignin-degrading microorganisms and enzymes associated with ligninolytic activity, which play a crucial role in the breakdown of lignocellulosic biomass. Analyzing multi-omics data highlights the potential value of fungal-produced enzymes in lignocellulosic material degradation, giving them an advantage in their ecological niches.
Lignin, a highly heterogeneous polymer of lignocellulosic biomass, is intricately associated with cellulose and hemicellulose, responsible for its strength and rigidity. Lignin decomposition is carried out through certain enzymes derived from microorganisms to promote the hydrolysis of lignin. Analyzing multi-omics data helps to emphasize the probable value of fungal-produced enzymes to degrade the lignocellulosic material, which pro-vides them an advantage in their ecological niches. This review focuses on lignin biodegrading microorganisms and associated ligninolytic enzymes, including lignin peroxidase, manganese peroxidase, versatile peroxidase, laccase, and dye-decolorizing peroxidase. Further, enzymatic catalysis, lignin biodegradation mechanisms, vital factors responsible for lignin modification and degradation, and the design and selection of practical metabolic
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