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Maude Fer et al.
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Tomohide Uno et al.
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Important amino acid residues that confer CYP2C19 selective activity to CYP2C9
Yasunobu Wada et al.
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J. Rosemary et al.
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N. Hanioka et al.
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Alexander Seifert et al.
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MH Choi et al.
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B Wang et al.
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PA Williams et al.
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C Xu et al.
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