相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。New understanding of multidrug efflux and permeation in antibiotic resistance, persistence, and heteroresistance
Pedro D. Manrique et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2023)
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics
Inga V. Leus et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2023)
Property space mapping of Pseudomonas aeruginosa permeability to small molecules
Inga V. Leus et al.
SCIENTIFIC REPORTS (2022)
Structure-Uptake Relationship Studies of Oxazolidinones in Gram- Negative ESKAPE Pathogens
Ziwei Hu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
An Iterative Approach Guides Discovery of the Fabl Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections
Erica N. Parker et al.
ACS CENTRAL SCIENCE (2022)
Facilitating Compound Entry as a Means to Discover Antibiotics for Gram-Negative Bacteria
Kristen A. Munoz et al.
ACCOUNTS OF CHEMICAL RESEARCH (2021)
The Whole Is Bigger than the Sum of Its Parts: Drug Transport in the Context of Two Membranes with Active Efflux
Valentin V. Rybenkov et al.
CHEMICAL REVIEWS (2021)
Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens
Erica N. Parker et al.
NATURE MICROBIOLOGY (2020)
Gram-Negative Antibiotic Active Through Inhibition of an Essential Riboswitch
Stephen E. Motika et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Defining new chemical space for drug penetration into Gram-negative bacteria
Shibin Zhao et al.
NATURE CHEMICAL BIOLOGY (2020)
Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors
Michaelyn C. Lux et al.
JOURNAL OF ANTIBIOTICS (2019)
Development and Optimization of a Higher-Throughput Bacterial Compound Accumulation Assay
Marcella Widya et al.
ACS INFECTIOUS DISEASES (2019)
Advances and challenges in bacterial compound accumulation assays for drug discovery
David A. Six et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2018)
Antibacterial Drug Discovery: Some Assembly Required
Ruben Tommasi et al.
ACS INFECTIOUS DISEASES (2018)
Evaluating LC-MS/MS To Measure Accumulation of Compounds within Bacteria
Ramkumar Iyer et al.
ACS INFECTIOUS DISEASES (2018)
Predictive compound accumulation rules yield a broad - spectrum antibiotic
Michelle F. Richter et al.
NATURE (2017)
A Gestalt approach to Gram-negative entry
Lynn L. Silver
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors
Matthew R. Bockman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Synthesis and Pharmacokinetic Evaluation of Siderophore Biosynthesis Inhibitors for Mycobacterium tuberculosis
Kathryn M. Nelson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It
Helen I. Zgurskaya et al.
ACS INFECTIOUS DISEASES (2015)
General Platform for Systematic Quantitative Evaluation of Small-Molecule Permeability in Bacteria
Tony D. Davis et al.
ACS CHEMICAL BIOLOGY (2014)
N-Substituted 2-Aminobiphenylpalladium Methanesulfonate Precatalysts and Their Use in C-C and C-N Cross-Couplings
Nicholas C. Bruno et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
TRANSLOCATION Project: How to Get Good Drugs into Bad Bugs
Robert A. Stavenger et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Recover the lost art of drug discovery
Kim Lewis
NATURE (2012)
Electric-Field-Responsive Handle for Large-Area Orientation of Discotic Liquid-Crystalline Molecules in Millimeter-Thick Films
Daigo Miyajima et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
Jonathan B. Baell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis of 1,3-Diamines Through Rhodium-Catalyzed C-H Insertion
Toshiki Kurokawa et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Mechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesis
Xuequan Lu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Inhibition of Siderophore Biosynthesis by 2-Triazole Substituted Analogues of 5'-O-[N-(Salicyl)sulfamoyl]adenosine: Antibacterial Nucleosides Effective against Mycobacterium tuberculosis
Amol Gupte et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues:: Structure-activity relationships of the nucleobase domain of 5′-O-[N-(salicyl)sulfamoyl]adenosine
Joao Neres et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of Mycobacterium tuberculosis
RV Somu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
2,5′-disubstituted adenosine derivatives:: Evaluation of selectivity and efficacy for the adenosine A1, A2A, and A3 receptor
EW van Tilburg et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)