相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Overexpression of protein disulfide isomerase enhances vitamin K epoxide reductase activity
Thomas Chetot et al.
BIOCHEMISTRY AND CELL BIOLOGY (2022)
Structural features determining the vitamin K epoxide reduction activity in the VKOR family of membrane oxidoreductases
Guomin Shen et al.
FEBS JOURNAL (2022)
A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase
Xuejie Chen et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2021)
Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation
Shixuan Liu et al.
SCIENCE (2021)
Structural Investigation of the Vitamin K Epoxide Reductase (VKORC1) Binding Site with Vitamin K
Nolan Chatron et al.
BIOCHEMISTRY (2020)
Biomarkers Potency to Monitor Non-target Fauna Poisoning by Anticoagulant Rodenticides
Antoine Rached et al.
FRONTIERS IN VETERINARY SCIENCE (2020)
Determining the necessity of phenyl ring π-character in warfarin
Hui Xing et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu
Xuejie Chen et al.
BLOOD (2018)
Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer
Guomin Shen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Warfarin and vitamin K compete for binding to Phe55 in human VKOR
Katrin J. Czogalla et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer
Guomin Shen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Warfarin and vitamin K compete for binding to Phe55 in human VKOR
Katrin J. Czogalla et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Adaptative evolution of the Vkorc1 gene in Mus musculus domesticus is influenced by the selective pressure of anticoagulant rodenticides
Joffrey Goulois et al.
ECOLOGY AND EVOLUTION (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Synthesis and biological evaluation of C-3 aliphatic coumarins as vitamin K antagonists
Adrien Montagut-Romans et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Membrane Composition Influences the Activity of in Vitro Refolded Human Vitamin K Epoxide Reductase
Frank Jaenecke et al.
BIOCHEMISTRY (2015)
Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX
Alison E. Fohner et al.
PHARMACOGENETICS AND GENOMICS (2015)
The realm of vitamin K dependent proteins: Shifting from coagulation toward calcification
Brecht A. G. Willems et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2014)
Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces
Katrin J. Czogalla et al.
BLOOD (2013)
How Warfarin's Structural Diversity Influences Its Phospholipid Bilayer Membrane Permeation
Bjorn C. G. Karlsson et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) - The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations
Benjamin Matagrin et al.
FEBS OPEN BIO (2013)
Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone φ, ψ and Side-Chain χ1 and χ2 Dihedral Angles
Robert B. Best et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Derivation and Systematic Validation of a Refined All-Atom Force Field for Phosphatidylcholine Lipids
Joakim P. M. Jambeck et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
VKORC1 mutations detected in patients resistant to vitamin K antagonists are not all associated with a resistant VKOR activity
A. Hodroge et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)
SwissParam: A Fast Force Field Generation Tool for Small Organic Molecules
Vincent Zoete et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment
M. Watzka et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2011)
Open Babel: An open chemical toolbox
Noel M. O'Boyle et al.
JOURNAL OF CHEMINFORMATICS (2011)
Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives
Omaima M. Abdelhafez et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Synthesis and Insecticidal Activity of New 4-Hydroxy-2H-1-benzopyran-2-one Derivatives
Meijing Wang et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2009)
Novel mutations in the VKORC1 gene of wild rats and mice - a response to 50 years of selection pressure by warfarin?
Simone Rost et al.
BMC GENETICS (2009)
The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children
Marieke J. H. van Summeren et al.
BRITISH JOURNAL OF NUTRITION (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
VKORC1:: molecular target of coumarins
J. Oldenburg et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2007)
The conversion of vitamin K epoxide to vitamin K quinone and vitamin K quinone to vitamin K hydroquinone uses the same active site cysteines
Da-Yun Jin et al.
BIOCHEMISTRY (2007)
Synthesis and structure-activity relationships of novel warfarin derivatives
Markus Gebauer
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
GROMACS: Fast, flexible, and free
D Van der Spoel et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors
DU Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Comparative pharmacokinetics of vitamin K antagonists - Warfarin, phenprocoumon and acenocoumarol
M Ufer
CLINICAL PHARMACOKINETICS (2005)
Identification of the gene for vitamin K epoxide reductase
T Li et al.
NATURE (2004)
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
S Rost et al.
NATURE (2004)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)
分享论文
