4.7 Article

Maslinic acid solid lipid nanoparticles as hydrophobic anticancer drug carriers: Formulation, in vitro activity and in vivo biodistribution

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Plant Sciences

Maslinic acid exerts anticancer effects by targeting cancer hallmarks

Kai Xin Ooi et al.

Summary: This is the first systematic review on the anticancer properties of maslinic acid (MA) targeting cancer hallmarks. The review summarizes the antineoplastic activities of MA and its diverse mechanisms of action based on the effects on each hallmark. Rating: 8 out of 10.

PHYTOMEDICINE (2023)

Article Chemistry, Physical

Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment

Pablo Gravan et al.

Summary: Nanotechnological drug delivery platforms, specifically lipid-core nanoparticles (LCNPs), have gained significant interest in cancer therapeutics due to their ability to improve the pharmacokinetic profile and distribution of chemotherapeutic agents. However, there is a lack of consensus regarding the terminology and classification of LCNPs. This review provides a comprehensive understanding of LCNPs defined and classified as liquid lipid nanoparticles (LLNs) and discusses their preparation methods, routes of administration, and physicochemical properties for efficient antitumoral drug delivery.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2023)

Article Pharmacology & Pharmacy

Solid lipid nanoparticles to improve bioaccessibility and permeability of orally administered maslinic acid

Aixa Aguilera-Garrido et al.

Summary: Maslinic acid (MA), a low water-soluble compound derived from plants, has been formulated into solid lipid nanoparticles (SLNs) to improve its solubility and bioaccessibility for effective antitumor activity. SLNs can serve as nanocarriers for hydrophobic antitumor compounds and have demonstrated stability and suitability for oral consumption.

DRUG DELIVERY (2022)

Article Chemistry, Multidisciplinary

Silver Nanoparticles from Annona muricata Peel and Leaf Extracts as a Potential Potent, Biocompatible and Low Cost Antitumor Tool

Maria G. Gonzalez-Pedroza et al.

Summary: In this study, silver nanoparticles were successfully synthesized using extracts from Annona muricata, showing a more potent anti-tumor effect in fruit peel extract compared to leaf extract. The nanoparticles demonstrated significant cancer cell destruction capabilities at low concentrations, making them a promising and cost-effective tool for cancer treatment.

NANOMATERIALS (2021)

Review Pharmacology & Pharmacy

Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

Mingming Zhang et al.

Summary: This review discusses the challenges and mechanisms of nanoparticle infiltration in tumor microenvironment, as well as the strategies for enhancing therapeutic efficacy through adjusting the characteristics and structure of nanoparticles. The comprehensive summary provided in this review aims to guide future research in improving cancer treatment outcomes.

ACTA PHARMACEUTICA SINICA B (2021)

Article Nutrition & Dietetics

Maslinic Acid Attenuates Denervation-Induced Loss of Skeletal Muscle Mass and Strength

Yuki Yamauchi et al.

Summary: The study found that Maslinic acid has the potential to prevent denervated muscle atrophy and enhance muscle strength, possibly through regulating various biological processes and signaling pathways. Therefore, this compound may serve as a new dietary ingredient for the treatment and prevention of muscle atrophy.

NUTRIENTS (2021)

Article Pharmacology & Pharmacy

Endocytic Uptake of Solid Lipid Nanoparticles by the Nasal Mucosa

Ammar S. Al Khafaji et al.

Summary: Nanoparticles administered via the nasal cavity demonstrated uptake through various endocytic pathways, with continued uptake observed even after exposure to pharmacological inhibitors. The study revealed that a combination of endocytic pathways are involved in the transfer of nanoparticles into the nasal mucosa. Additionally, non-energy-dependent pathways for nanoparticle uptake were observed following exposure to general metabolic inhibitors, highlighting the potential for lipid nanoparticles in local and systemic drug delivery following nasal administration.

PHARMACEUTICS (2021)

Review Biochemistry & Molecular Biology

A Review of Curcumin and Its Derivatives as Anticancer Agents

Mhd Anas Tomeh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Agriculture, Multidisciplinary

Maslinic Acid Inhibits Colon Tumorigenesis by the AMPK-mTOR Signaling Pathway

Qing Wei et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Review Pharmacology & Pharmacy

An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites

Mohamed F. Attia et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2019)

Review Nutrition & Dietetics

Dietary Curcumin: Correlation between Bioavailability and Health Potential

Michele Dei Cas et al.

NUTRIENTS (2019)

Article Nutrition & Dietetics

Maslinic acid derived from olive fruit in combination with resistance training improves muscle mass and mobility functions in the elderly

Narumi Nagai et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2019)

Review Pharmacology & Pharmacy

Mucosal Applications of Poloxamer 407-Based Hydrogels: An Overview

Elena Giuliano et al.

PHARMACEUTICS (2018)

Article Chemistry, Medicinal

Synthesis and in vitro antiproliferative evaluation of PEGylated triterpene acids

Marta Medina-O'Donnell et al.

FITOTERAPIA (2017)

Review Cell Biology

Overviews on the cellular uptake mechanism of polysaccharide colloidal nanoparticles

Sara Salatin et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017)

Article Nutrition & Dietetics

Maslinic acid improves quality of life by alleviating joint knee pain in the elderly: results from a community-based pilot study

Satoshi Fukumitsu et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2017)

Review Chemistry, Multidisciplinary

Cellular uptake of nanoparticles: journey inside the cell

Shahed Behzadi et al.

CHEMICAL SOCIETY REVIEWS (2017)

Article Nanoscience & Nanotechnology

Transport Mechanisms of Solid Lipid Nanoparticles across Caco-2 Cell Monolayers and their Related Cytotoxicology

Gui-Hong Chai et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Review Biochemistry & Molecular Biology

Triterpenes in cancer: significance and their influence

Balraj Singh Gill et al.

MOLECULAR BIOLOGY REPORTS (2016)

Article Agriculture, Multidisciplinary

Identification in Rat Plasma and Urine by Linear Trap Quadrupole-Orbitrap Mass Spectrometry of the Metabolites of Maslinic Acid, a Triterpene from Olives

Marta Sanchez-Gonzalez et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

Review Pharmacology & Pharmacy

Nanoprecipitation and the Ouzo effect: Application to drug delivery devices

Elise Lepeltier et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

Article Chemistry, Physical

Block copolymers at interfaces: Interactions with physiological media

Amelia Torcello-Gomez et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2014)

Review Biochemistry & Molecular Biology

Maslinic Acid, a Natural Phytoalexin-Type Triterpene from Olives - A Promising Nutraceutical?

Gloria Lozano-Mena et al.

MOLECULES (2014)

Review Agriculture, Multidisciplinary

Bioactive Properties of the Main Triterpenes Found in Olives, Virgin Olive Oil, and Leaves of Olea europaea

Cristina Sanchez-Quesada et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

Article Food Science & Technology

Assessment of the safety of maslinic acid, a bioactive compound from Olea europaea L.

Marta Sanchez-Gonzalez et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2013)

Review Pharmacology & Pharmacy

Lipid nanoparticles: state of the art, new preparation methods and challenges in drug delivery

Luigi Battaglia et al.

EXPERT OPINION ON DRUG DELIVERY (2012)

Article Chemistry, Multidisciplinary

Effect of Gold Nanoparticle Aggregation on Cell Uptake and Toxicity

Alexandre Albanese et al.

ACS NANO (2011)

Review Pharmacology & Pharmacy

Pancreatic Cancer: Pathobiology, Treatment Options, and Drug Delivery

Jing Li et al.

AAPS JOURNAL (2010)

Article Chemistry, Physical

Novel core-shell lipid-chitosan and lipid-poloxamer nanocapsules: stability by hydration forces

Manuel J. Santander-Ortega et al.

COLLOID AND POLYMER SCIENCE (2010)

Article Pharmacology & Pharmacy

Influence of polymer behaviour in organic solution on the production of polylactide nanoparticles by nanoprecipitation

Philippe Legrand et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Article Agriculture, Multidisciplinary

Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity

Xiangjiu He et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)

Review Plant Sciences

Natural products as sources of new drugs over the last 25 years

David J. Newman et al.

JOURNAL OF NATURAL PRODUCTS (2007)

Article Nutrition & Dietetics

Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells

M. Emilia Juan et al.

JOURNAL OF NUTRITION (2006)

Article Chemistry, Multidisciplinary

Long circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumors

MN Khalid et al.

PHARMACEUTICAL RESEARCH (2006)

Review Pharmacology & Pharmacy

Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles

DE Owens et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)

Article Pharmacology & Pharmacy

Nanostructured lipid matrices for improved microencapsulation of drugs

RH Müller et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2002)

Review Chemistry, Multidisciplinary

On the importance and mechanisms of burst release in matrix-controlled drug delivery systems

X Huang et al.

JOURNAL OF CONTROLLED RELEASE (2001)

Review Pharmacology & Pharmacy

Solid lipid nanoparticles -: Production, characterization and applications

W Mehnert et al.

ADVANCED DRUG DELIVERY REVIEWS (2001)