Inspired by spider silk spinning, a method for producing tough filaments using 3D bioprinting and salting-out of the protein was developed. A blend of natural polymer gelatin and viscoelastic G-polymer networks, as well as inorganic nanoparticles, was used to enhance stiffness, ductility, and 3D printing properties. The resulting self-healing nanocomposite hydrogel exhibited exceptional mechanical properties, biocompatibility, shear thinning behavior, and a controlled gelation mechanism for 3D printing.
Taking inspiration from spider silk protein spinning, we developed a method to produce tough filaments using extrusion-based 3D bioprinting and salting-out of the protein. To enhance both stiffness and ductility, we have designed a blend of partially crystalline, thermally sensitive natural polymer gelatin and viscoelastic G-polymer networks, mimicking the components of spider silk. Additionally, we have incorporated inorganic nanoparticles as a rheological modifier to fine-tune the 3D printing properties. This self-healing nanocomposite hydrogel exhibits exceptional mechanical properties, biocompatibility, shear thinning behavior, and a well-controlled gelation mechanism for 3D printing.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据