4.6 Article

Structure-guided approach to modify the substrate specificity of the protein human deglycase-1 (hDJ-1)

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Physical

Elucidating Residue-Level Determinants Affecting Dimerization of Ebola Virus Matrix Protein Using High-Throughput Site Saturation Mutagenesis and Biophysical Approaches

Yogesh B. B. Narkhede et al.

Summary: The Ebola virus acquires its lipid envelope from the plasma membrane of the host cell it infects. The matrix protein VP40, which mediates the virus assembly and budding, is composed of two domains that are loosely linked. Computational and experimental studies have identified key residues that contribute to the stability of the VP40 dimer form.

JOURNAL OF PHYSICAL CHEMISTRY B (2023)

Article Chemistry, Multidisciplinary

Software update: The ORCA program system-Version 5.0

Frank Neese

Summary: The latest version 5.0 of the ORCA quantum chemistry program suite represents a significant improvement in performance, numerical robustness, functionality, and user friendliness.

WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2022)

Review Biochemistry & Molecular Biology

Understanding the role of glycation in the pathology of various non-communicable diseases along with novel therapeutic strategies

Nilima S. Bangar et al.

Summary: Glycation refers to the reaction between reducing sugars and free amino groups in proteins, resulting in the formation of various products. Glycation plays a significant role in metabolic diseases, brain disorders, aging, and gut microbiome dysregulation. It affects the development of diseases by altering protein structure and function.

GLYCOBIOLOGY (2022)

Article Chemistry, Multidisciplinary

Computational Chemistry Activities with Avogadro and ORCA

Henry David Snyder et al.

Summary: This article describes computational chemistry modeling activities that took place as part of a physical chemistry course, outlining the main software tools used by students and specific activities. These activities are suitable for general chemistry and physical chemistry laboratory courses and are suitable for virtual learning environments.

JOURNAL OF CHEMICAL EDUCATION (2021)

Article Cell Biology

Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells

Ursula Kern et al.

Summary: DJ-1 is a crucial component of cellular proteomes, with its C-terminal helix 8 playing a key role in deglycation activity. The presence or absence of helix 8 in DJ-1 significantly impacts mitochondrial and lysosomal biology. The pleiotropic nature of DJ-1 is further demonstrated by its indirect modulation of lysosomal protease activity.
Article Multidisciplinary Sciences

DJ-1 attenuates the glycation of mitochondrial complex I and complex III in the post-ischemic heart

Yvanna Pantner et al.

Summary: DJ-1 plays a key role in modulating glycation of mitochondrial electron transport complexes I and III after myocardial ischemia-reperfusion injury, maintaining mitochondrial function and potentially serving as a therapeutic target for post-ischemic heart recovery.

SCIENTIFIC REPORTS (2021)

Review Biophysics

Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease

Ludmila P. Dolgacheva et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2019)

Article Biochemistry & Molecular Biology

Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration?

Irwin K. Cheah et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Review Biochemistry & Molecular Biology

The glyoxalase pathway: the first hundred years ... and beyond

Marta Sousa Silva et al.

BIOCHEMICAL JOURNAL (2013)

Article Chemistry, Multidisciplinary

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

Jing Huang et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2013)

Review Cell Biology

Neuroprotective Function of DJ-1 in Parkinson's Disease

Hiroyoshi Ariga et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Review Biochemistry & Molecular Biology

Lipid glycation and protein glycation in diabetes and atherosclerosis

Teruo Miyazawa et al.

AMINO ACIDS (2012)

Article Biochemistry & Molecular Biology

Genetic and epigenetic contribution to complex traits

Helena Kilpinen et al.

HUMAN MOLECULAR GENETICS (2012)

Article Chemistry, Medicinal

Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing

K. Vanommeslaeghe et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)

Article Biochemistry & Molecular Biology

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

Xinglong Wang et al.

JOURNAL OF NEUROCHEMISTRY (2012)

Review Biochemistry & Molecular Biology

DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders

Philipp J. Kahle et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Article Chemistry, Physical

Structure and dynamics of the TIP3P, SPC, and SPC/E water models at 298 K

P Mark et al.

JOURNAL OF PHYSICAL CHEMISTRY A (2001)