4.6 Article

Nicotinamide mononucleotide pretreatment improves long-term isoflurane anesthesia-induced cognitive impairment in mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Isoflurane activates AMP-activated protein kinase to inhibit proliferation, and promote apoptosis and autophagy in cervical carcinoma bothin vitroandin vivo

Hongfang Wei et al.

Summary: This study revealed that isoflurane activates AMPK to inhibit proliferation, promote apoptosis, and induce autophagy in cervical cancer cells both in vitro and in vivo. Additionally, isoflurane was found to repress tumorigenesis, activate AMPK, and induce autophagy in a xenograft mouse model.

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2021)

Article Chemistry, Multidisciplinary

DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress

Bei-ni Wang et al.

Summary: DL-3-n-Butylphthalide (DL-NBP), extracted from Chinese celery seeds, shows neuroprotective effects by improving cognitive decline associated with diabetes, including enhancing learning and memory function, reducing morphological changes, increasing neuronal survival, and restoring synaptic protein levels and dendritic density in the hippocampus. Additionally, DL-NBP decreases oxidative stress through Nrf2/HO-1 signaling and boosts brain-derived neurotrophic factor (BDNF) expression via PI3K/Akt/CREB signaling, suggesting its potential as a pharmacologic treatment for DACD.

ACTA PHARMACOLOGICA SINICA (2021)

Review Cardiac & Cardiovascular Systems

NAD+ Metabolism in Cardiac Health, Aging, and Disease

Mahmoud Abdellatif et al.

Summary: NAD(+) plays a crucial role in metabolic health and age-related diseases, with supplementation showing positive effects. Decline in NAD(+) pools is associated with cardiovascular disease risk factors, and replenishment can improve related conditions.

CIRCULATION (2021)

Review Cell Biology

NAD+ metabolism and its roles in cellular processes during ageing

Anthony J. Covarrubias et al.

Summary: NAD(+) is a crucial coenzyme in redox reactions and plays a pivotal role in energy metabolism. Its levels decline with age, and raising NAD(+) levels is being explored as a potential strategy to extend human lifespan and healthspan. NAD(+) influences key cellular processes and functions, including metabolic pathways, DNA repair, and cellular senescence, with implications for healthy aging and age-related diseases.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

Article Oncology

Nicotinamide Mononucleotide Prevents Cisplatin-Induced Cognitive Impairments

Ki Hyun Yoo et al.

Summary: Chemotherapy-induced cognitive impairment (CICI) is a significant medical problem, but by increasing NAD(+) levels, it is possible to prevent and treat nerve damage caused by cisplatin, thus improving the quality of life for patients.

CANCER RESEARCH (2021)

Article Urology & Nephrology

Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy

Itaru Yasuda et al.

Summary: Short-term NMN treatment in diabetic db/db mice can ameliorate symptoms of diabetic nephropathy and have remote renal protective effects, improving survival rates.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

Article Multidisciplinary Sciences

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women

Mihoko Yoshino et al.

Summary: The study demonstrates that NMN supplementation can enhance insulin sensitivity, insulin signaling, and remodeling in women with prediabetes who are overweight or obese, improving their metabolic function.

SCIENCE (2021)

Article Biochemistry & Molecular Biology

Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons

Krish Chandrasekaran et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

The differential effects of isoflurane and sevoflurane on neonatal mice

Shuai Zhao et al.

SCIENTIFIC REPORTS (2020)

Article Neurosciences

Autophagy Stimulation Decreases Dopaminergic Neuronal Death Mediated by Oxidative Stress

Marcela J. Ramirez-Moreno et al.

MOLECULAR NEUROBIOLOGY (2019)

Article Biochemistry & Molecular Biology

Green tea polyphenols improve isoflurane-induced cognitive impairment via modulating oxidative stress

Yuting Song et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2019)

Review Cell Biology

NAD+ in Brain Aging and Neurodegenerative Disorders

Sofie Lautrup et al.

CELL METABOLISM (2019)

Review Cell Biology

NAD metabolism: Implications in aging and longevity

Keisuke Yaku et al.

AGEING RESEARCH REVIEWS (2018)

Review Cell Biology

NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

Jun Yoshino et al.

CELL METABOLISM (2018)

Article Neurosciences

Anesthetic Isoflurane Induces DNA Damage Through Oxidative Stress and p53 Pathway

Cheng Ni et al.

MOLECULAR NEUROBIOLOGY (2017)

Review Pharmacology & Pharmacy

Oxidative Stress and the Central Nervous System

Samina Salim

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)

Review Cell Biology

NAD+ and sirtuins in aging and disease

Shin-ichiro Imai et al.

TRENDS IN CELL BIOLOGY (2014)

Review Neurosciences

Oxidative stress in Alzheimer's disease

Zhichun Chen et al.

NEUROSCIENCE BULLETIN (2014)

Article Multidisciplinary Sciences

Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress

Yusuke S. Hori et al.

PLOS ONE (2013)

Article Anesthesiology

Postoperative delirium and cognitive dysfunction

S. Deiner et al.

BRITISH JOURNAL OF ANAESTHESIA (2009)

Review Neurosciences

Brain foods:: the effects of nutrients on brain function

Fernando Gomez-Pinilla

NATURE REVIEWS NEUROSCIENCE (2008)