4.6 Article

Continuous high-frequency repetitive transcranial magnetic stimulation at extremely low intensity affects exploratory behavior and spatial cognition in mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice

Marisol Soula et al.

Summary: The authors find that 40-Hz flickering light does not suppress A beta, activate microglia or engage native gamma oscillations. Thus, visual flicker stimulation may not be a viable mechanism for altering AD pathology and modulating deep structures.

NATURE NEUROSCIENCE (2023)

Review Psychology, Clinical

Cognitive Effects Following Offline High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS) in Healthy Populations: A Systematic Review and Meta-Analysis

Mei Xu et al.

Summary: High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) is a commonly used treatment for neuropsychiatric disorders. A systematic review and meta-analysis were conducted to examine the cognitive effects of offline HF-rTMS in healthy individuals. Excitatory HF-rTMS showed small sized effects in improving accuracy and reaction time across all cognitive domains, with a relatively greater effect on executive functioning. Future research is needed to investigate cognitive enhancement from offline HF-rTMS in clinical populations.

NEUROPSYCHOLOGY REVIEW (2023)

Article Medicine, Research & Experimental

The Efficacy of High- or Low-Frequency Transcranial Magnetic Stimulation in Alzheimer's Disease Patients with Behavioral and Psychological Symptoms of Dementia

Wei Jiang et al.

Summary: The study found that high-frequency TMS has the advantages of fast results, good efficacy, and high safety for treating psychobehavioral abnormalities in AD patients, and can further improve cognitive function.

ADVANCES IN THERAPY (2022)

Article Neurosciences

Cognitive Improvement via Left Angular Gyrus-Navigated Repetitive Transcranial Magnetic Stimulation Inducing the Neuroplasticity of Thalamic System in Amnesic Mild Cognitive Impairment Patients

Zhiyuan Yang et al.

Summary: Stimulating superficial brain regions associated with the hippocampus can improve memory in Alzheimer's disease patients. This study used neuro-navigated rTMS to stimulate the left angular gyrus and observed neuroplasticity of brain networks and improvement in cognitive abilities.

JOURNAL OF ALZHEIMERS DISEASE (2022)

Article Neurosciences

Combination of repetitive transcranial magnetic stimulation and treadmill training reduces hyperreflexia by rebalancing motoneuron excitability in rats after spinal cord contusion

Shuangyan Wang et al.

Summary: By combining repetitive transcranial magnetic stimulation (rTMS) with treadmill training (Tr), researchers found that there may be a synergistic effect in alleviating spasticity and improving motor dysfunction after spinal cord injury (SCI) in rats.

NEUROSCIENCE LETTERS (2022)

Review Biochemical Research Methods

Use of transcranial magnetic stimulation for studying the neural basis of numerical cognition: A systematic review

Sara Garcia-Sanz et al.

Summary: This systematic review synthesizes the evidence from various TMS protocols on the neural basis of numerical cognition in healthy adults. The results show that TMS applied to regions of the parietal cortex and prefrontal cortex has neuromodulatory effects on numerical cognition, affecting cognitive functions related to arithmetic, numerical, and magnitude processing.

JOURNAL OF NEUROSCIENCE METHODS (2022)

Article Geriatrics & Gerontology

Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer's-Like Disease Model

Andjela Stekic et al.

Summary: The study evaluated the effects of intermittent theta burst stimulation (iTBS) in a trimethyltin (TMT)-induced Alzheimer's-like disease model, showing that iTBS can improve cognition and reduce inflammation, possibly through modulation of the PI3K/Akt/mTOR signaling pathway.

FRONTIERS IN AGING NEUROSCIENCE (2022)

Article Biochemistry & Molecular Biology

Repetitive Transcranial Magnetic Stimulation (rTMS) of Dorsolateral Prefrontal Cortex May Influence Semantic Fluency and Functional Connectivity in Fronto-Parietal Network in Mild Cognitive Impairment (MCI)

Sabrina Esposito et al.

Summary: This preliminary study aimed to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on patients with mild cognitive impairment (MCI). The results showed significant improvements in executive performance and changes in brain functional connectivity (FC) in MCI patients who received rTMS treatment.

BIOMEDICINES (2022)

Article Neurosciences

5 Hz of repetitive transcranial magnetic stimulation improves cognition and induces modifications in hippocampal neurogenesis in adult female Swiss Webster mice

Gerardo Bernabe Ramirez-Rodriguez et al.

Summary: This study investigated the effects of repetitive transcranial magnetic stimulation (rTMS) on cognition, neurogenic-associated modifications, and neuronal activation in the hippocampus of female Swiss Webster mice. The results showed that rTMS twice a day for 14 days improved cognition and increased cell proliferation, doublecortin cells, dendrite morphology, c-Fos expression, and FosB/Delta-FosB immunoreactivity in the mice. The volume of the granular cell layer, mossy fibers, and CA3 also increased. These findings suggest that rTMS can enhance cognitive behavior, cell proliferation, and neuronal activation in healthy mice.

BRAIN RESEARCH BULLETIN (2022)

Review Biochemistry & Molecular Biology

Repetitive transcranial magnetic stimulation (rTMS) for multiple neurological conditions in rodent animal models: A systematic review

Xuemei Zong et al.

Summary: rTMS has shown promising therapeutic value in rodent models of stroke, Alzheimer's disease, vascular dementia, and Parkinson's disease. However, the optimal protocols and exact target of action for this therapy remain to be determined. Therefore, further research is needed to bridge the translation gap between rodent experiments and clinical application, which might lead to new directions in the treatment of multiple neurological disorders.

NEUROCHEMISTRY INTERNATIONAL (2022)

Article Neurosciences

High-frequency repetitive transcranial magnetic stimulation improves spatial episodic learning and memory performance by regulating brain plasticity in healthy rats

Qi Wu et al.

Summary: This study aimed to investigate the effects of HF-rTMS on cognition and its underlying mechanisms. The results showed that HF-rTMS can enhance cognitive performance through modulation of NMDA receptor-dependent brain plasticity.

FRONTIERS IN NEUROSCIENCE (2022)

Article Neurosciences

Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation

Shrey Grover et al.

Summary: This study describes a transcranial alternating current stimulation (tACS) protocol that selectively enhances working memory and long-term memory in older adults. By modulating low or high-frequency activity in specific brain areas, memory improvements can be sustained after intervention, with the rate of memory improvement predicting long-term effects, particularly for individuals with lower baseline cognitive function.

NATURE NEUROSCIENCE (2022)

Article Geriatrics & Gerontology

Anodal and cathodal transcranial direct current stimulations of prefrontal cortex in a rodent model of Alzheimer's disease

Mengsi Duan et al.

Summary: This study examined the effects of transcranial direct current stimulation (tDCS) on brain function in a mouse model of Alzheimer's disease (AD). The results showed that tDCS improved spatial learning and memory in AD mice and altered their electroencephalogram (EEG) activities. These findings highlight the potential of tDCS in restoring neural network activity and improving cognition in AD.

FRONTIERS IN AGING NEUROSCIENCE (2022)

Article Geriatrics & Gerontology

Long-term gamma transcranial alternating current stimulation improves the memory function of mice with Alzheimer's disease

Linyan Wu et al.

Summary: The study found that long-term gamma-frequency tACS can reduce Aβ levels, increase gamma oscillation power, and ultimately improve short-term memory function in an AD mouse model. In comparison, the short-term tACS treatment showed less significant effects.

FRONTIERS IN AGING NEUROSCIENCE (2022)

Review Clinical Neurology

Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines

Simone Rossi et al.

Summary: This article is based on a consensus conference held in Siena, Italy in October 2018, aiming to update safety guidelines for the application of transcranial magnetic stimulation (TMS). New emerging issues discussed include safety concerns with recently developed stimulation devices, novel scenarios of TMS applications, and ethical considerations regarding neuroenhancement.

CLINICAL NEUROPHYSIOLOGY (2021)

Article Neurosciences

Improved Cognitive Promotion through Accelerated Magnetic Stimulation

Xingqi Wu et al.

Summary: This study compared the effects of traditional HF-rTMS and TBS protocols on cognitive enhancement in healthy controls. The results showed that intermittent TBS has a significant promoting effect on working memory and executive function, performing better than traditional HF-rTMS.

ENEURO (2021)

Review Neurosciences

Precise Modulation Strategies for Transcranial Magnetic Stimulation: Advances and Future Directions

Gangliang Zhong et al.

Summary: Transcranial magnetic stimulation (TMS) is a popular modulatory technique for the noninvasive diagnosis and therapy of neurological and psychiatric diseases, but current modulation strategies are only moderately effective. The effects of TMS vary depending on device components and stimulation protocols, highlighting the importance of designing precise modulatory strategies in clinical or research applications. Recent advancements in combining TMS with neuroimaging techniques show promising potential for probing affected brain areas and predicting research directions aimed at precisely targeting and remodeling impaired cortices or circuits.

NEUROSCIENCE BULLETIN (2021)

Article Neurosciences

Immediate and cumulative effects of high-frequency repetitive transcranial magnetic stimulation on cognition and neuronal excitability in mice

Haijun Zhu et al.

Summary: This study investigated the effects of high-frequency rTMS on cognition and neuronal excitability in mice using different intervention protocols. Results showed that chronic high-frequency rTMS led to improved cognition and increased neuronal excitability, while short-term stimulation and in vitro stimulation had less noticeable effects.

NEUROSCIENCE RESEARCH (2021)

Article Neurosciences

Repetitive Transcranial Magnetic Stimulation as an Add-On Treatment for Cognitive Impairment in Alzheimer's Disease and Its Impact on Self-Rated Quality of Life and Caregiver's Burden

Juliana Teti Mayer et al.

Summary: This study explored the effects of repetitive transcranial magnetic stimulation (rTMS) on Alzheimer's disease (AD) patients, finding significant improvements in semantic memory and reduction in anxiety levels. These findings suggest that targeting these features in AD could be important for treatment strategies aimed at enhancing quality of life and cognitive function.

BRAIN SCIENCES (2021)

Article Biochemistry & Molecular Biology

Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition

Anthony J. Martorell et al.

Article Biochemistry & Molecular Biology

Effects of exposure to extremely low frequency electromagnetic fields on hippocampal long-term potentiation in hippocampal CA1 region

Yu Zheng et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Low intensity repetitive transcranial magnetic stimulation modulates skilled motor learning in adult mice

Alexander D. Tang et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Gamma frequency entrainment attenuates amyloid load and modifies microglia

Hannah F. Iaccarino et al.

NATURE (2016)

Review Neurosciences

Potentials and limits to enhance cognitive functions in healthy and pathological aging by tDCS

Kristin Prehn et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2015)

Article Public, Environmental & Occupational Health

Toxic effects of 50 Hz electromagnetic field on memory consolidation in male and female mice

Elham Foroozandeh et al.

TOXICOLOGY AND INDUSTRIAL HEALTH (2013)

Article Neurosciences

Stochastic Resonance Effects Reveal the Neural Mechanisms of Transcranial Magnetic Stimulation

Dietrich Samuel Schwarzkopf et al.

JOURNAL OF NEUROSCIENCE (2011)

Review Geriatrics & Gerontology

Non-invasive brain stimulation: enhancing motor and cognitive functions in healthy old subjects

Maximo Zimerman et al.

FRONTIERS IN AGING NEUROSCIENCE (2010)

Article Neurosciences

Simply longer is not better: reversal of theta burst after-effect with prolonged stimulation

Olga Lucia Gamboa et al.

EXPERIMENTAL BRAIN RESEARCH (2010)

Article Pharmacology & Pharmacy

Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice

Yu Fu et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2008)

Review Neurosciences

Transcranial magnetic stimulation: A primer

Mark Hallett

NEURON (2007)

Article Behavioral Sciences

Motor and phosphene thresholds: a transcranial magnetic stimulation correlation study

LM Stewart et al.

NEUROPSYCHOLOGIA (2001)