相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease
Jacqueto Zephyr et al.
BIOORGANIC CHEMISTRY (2023)
SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases
Hannah Maus et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2021)
Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease
Shenyou Nie et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Synthesis, Structure-Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease
Shenyou Nie et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture
Nikos Kuehl et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Next Generation Therapeutics for the Treatment of Myelofibrosis
Douglas Tremblay et al.
CELLS (2021)
Facile Synthesis and In Vitro Activity of N-Substituted 1,2-Benzisothiazol-3(2H)-ones against Dengue Virus NS2BNS3 Protease
Farwa Batool et al.
PATHOGENS (2021)
Antitumor Activity of Nanoparticles Loaded with PHT-427, a Novel AKT/PDK1 Inhibitor, for the Treatment of Head and Neck Squamous Cell Carcinoma
Joaquin Yanes-Diaz et al.
PHARMACEUTICS (2021)
Synthesis and evaluation of novel S-benzyl- and S-alkylphthalimide-oxadiazole -benzenesulfonamide hybrids as inhibitors of dengue virus protease
Syeda Shamila Hamdani et al.
BIOORGANIC CHEMISTRY (2020)
Piceatannol: A natural stilbene for the prevention and treatment of cancer
Kishore Banik et al.
PHARMACOLOGICAL RESEARCH (2020)
Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses
Niklas J. Braun et al.
CHEMMEDCHEM (2020)
A New Class of Dengue and West Nile Virus Protease Inhibitors with Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays
Nikos Kuehl et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance
Rida Zahra et al.
PLOS ONE (2020)
AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy
Dorota K. Flak et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)
Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease
Yuan Yao et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
ABT737 enhances ovarian cancer cells sensitivity to cisplatin through regulation of mitochondrial fission via Sirt3 activation
Lin Hou et al.
LIFE SCIENCES (2019)
Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases
Benedikt Millies et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
Sajid Khan et al.
NATURE MEDICINE (2019)
Inhibition of Dengue Virus Protease by Eugeniin, Isobiflorin, and Biflorin Isolated from the Flower Buds of Syzygium aromaticum (Cloves)
Hafiza Nosheen Saleem et al.
ACS OMEGA (2019)
Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease
Zhong Li et al.
ANTIVIRAL RESEARCH (2018)
A quinoline compound inhibits the replication of dengue virus serotypes 1-4 in Vero cells
Hemalatha Beesetti et al.
ANTIVIRAL THERAPY (2018)
Potential targets for therapeutic intervention and structure based vaccine design against Zika virus
Amina Qadir et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Controversy and debate on dengue vaccine series-paper 1: review of a licensed dengue vaccine: inappropriate subgroup analyses and selective reporting may cause harm in mass vaccination programs
Antonio L. Dans et al.
JOURNAL OF CLINICAL EPIDEMIOLOGY (2018)
Development of antiviral inhibitor against dengue 2 targeting Ns3 protein: In vitro and in silico significant studies
P. Padmapriya et al.
ACTA TROPICA (2018)
TW37 enhances the pro-apoptosis and anti-migration ability of gefitinib in Non-Small Cell Lung Cancer
Xiaofan Chen et al.
CELLULAR AND MOLECULAR BIOLOGY (2018)
Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology
Christoph Nitsche et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Identification of fused bicyclic derivatives of pyrrolidine and imidazolidinone as dengue virus-2 NS2B-NS3 protease inhibitors
Zhibing Weng et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side
Kuan-Hung Lin et al.
JOURNAL OF VIROLOGY (2017)
A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease
Matthew Brecher et al.
PLOS PATHOGENS (2017)
The Medicinal Chemistry of Dengue Virus
Mira A. M. Behnam et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Epidemic arboviral diseases: priorities for research and public health
Annelies Wilder-Smith et al.
LANCET INFECTIOUS DISEASES (2016)
Discovery of Nanomolar Dengue and West Nile Virus Protease Inhibitors Containing a 4-Benzyloxyphenylglycine Residue
Mira A. M. Behnam et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Novel Dengue Virus NS2B/NS3 Protease Inhibitors
Hongmei Wu et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Biochemistry and Medicinal Chemistry of the Dengue Virus Protease
Christoph Nitsche et al.
CHEMICAL REVIEWS (2014)
Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245409 (XL765), a Novel, Orally Administered PI3K/mTOR Inhibitor in Patients with Advanced Solid Tumors
Kyriakos P. Papadopoulos et al.
CLINICAL CANCER RESEARCH (2014)
Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial
Maria Rosario Capeding et al.
LANCET (2014)
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
Muslum Yildiz et al.
ACS CHEMICAL BIOLOGY (2013)
NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex
Young Mee Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The global distribution and burden of dengue
Samir Bhatt et al.
NATURE (2013)
Burden of dengue fever is higher than previously thought
Anne Gulland
BMJ-BRITISH MEDICAL JOURNAL (2013)
Retro peptide-hybrids as selective inhibitors of the Dengue virus NS2B-NS3 protease
Christoph Nitsche et al.
ANTIVIRAL RESEARCH (2012)
Inhibition of Dengue virus and West Nile virus proteases by click chemistry-derived benz[d]isothiazol-3(2H)-one derivatives
Kok-Chuan Tiew et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation
Christian G. Noble et al.
JOURNAL OF VIROLOGY (2012)
Avogadro: an advanced semantic chemical editor, visualization, and analysis platform
Marcus D. Hanwell et al.
JOURNAL OF CHEMINFORMATICS (2012)
Novel Dengue Virus-Specific NS2B/NS3 Protease Inhibitor, BP2109, Discovered by a High-Throughput Screening Assay
Chi-Chen Yang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases
Christoph Nitsche et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F
Regina Cencic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Software News and Update AutoDock Vina: Improving the Speed and Accuracy of Docking with a New Scoring Function, Efficient Optimization, and Multithreading
Oleg Trott et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
The eIF4E/eIF4G Interaction Inhibitor 4EGI-1 Augments TRAIL-Mediated Apoptosis through c-FLIP Down-regulation and DR5 Induction Independent of Inhibition of Cap-Dependent Protein Translation
Songqing Fan et al.
NEOPLASIA (2010)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Promiscuous Aggregate-Based Inhibitors Promote Enzyme Unfolding
Kristin E. D. Coan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
Christin Tse et al.
CANCER RESEARCH (2008)
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus
P Erbel et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead
Z Yin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors
Z Yin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries
J Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T Oltersdorf et al.
NATURE (2005)
Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro
R Yusof et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)