期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 60, 页码 12134-12137出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc04417k
关键词
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资金
- NIH [1R01EB016721]
- NSF Research Fellowship [DGE-0707427]
Principal component analysis was applied to a biomaterial library of poly(beta-amino ester)s, useful for non-viral gene delivery, to elucidate chemical parameters that drive biological function. Correlative relationships and principal components were analyzed between 24 physico-chemical polymer properties and 3 cell-based functional variables in human glioblastoma cells (transfection, uptake, and viability).
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