4.7 Article

Screening bisphenols in complex samples via a planar Arxula adeninivorans bioluminescence bioassay

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Applied

Designed genotoxicity profiling detects genotoxic compounds in staple food such as healthy oils

Gertrud E. Morlock et al.

Summary: The current techniques used in food analysis do not consider genotoxic compounds. It is urgent to shift the paradigm in analytics towards non-target planar genotoxicity profiling to detect genotoxins. A study detected up to eight different genotoxins in 33 oils used for healthy diets, and identified genotoxic degradation products in oils stored open and closed for one month. High-resolution mass spectrometry revealed oxidized linolenic acid as the source of genotoxicity in all samples. Detoxification through on-surface S9 liver metabolization reduced most, but not all, genotoxins. By combining separation, effect detection, and simulated metabolization on the same surface, this profiling technique can identify sources of genotoxicity in food, feed, dietary supplements, and cosmetics. Its application will enhance understanding of food and its impact, as well as risk assessment and recommendations.

FOOD CHEMISTRY (2023)

Article Environmental Sciences

Bisphenol A and its alternatives in Austrian thermal paper receipts, and the migration from reusable plastic drinking bottles into water and artificial saliva using UHPLC-MS/MS

Rojin Banaderakhshan et al.

Summary: Bisphenol A (BPA) is a synthetic chemical identified as an endocrine disruptor and toxic to reproduction, mainly used in the production of plastics, but due to health and legal concerns, it is being replaced by other bisphenols.

CHEMOSPHERE (2022)

Article Biochemical Research Methods

High-performance thin-layer chromatography in combination with a yeast-based multi-effect bioassay to determine endocrine effects in environmental samples

Nicolai Baetz et al.

Summary: The study combines YMEES with HPTLC for simultaneous detection of estrogenic, androgenic, and gestagenic effects. The spraying approach showed higher sensitivity and precision compared to immersion for tested hormones.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2021)

Review Chemistry, Analytical

High-performance thin-layer chromatography combined with effect-directed assays and high-resolution mass spectrometry as an emerging hyphenated technology: A tutorial review

Gertrud E. Morlock

Summary: Hyphenated HPTLC technology has the potential to provide direct information on the effects of individual compounds in complex samples, helping to identify important compounds for further research. It offers efficient chromatographic separation and flexibility in operation, suitable for various fields.

ANALYTICA CHIMICA ACTA (2021)

Article Pharmacology & Pharmacy

Is Our Natural Food Our Homeostasis? Array of a Thousand Effect-Directed Profiles of 68 Herbs and Spices

Tamara Schreiner et al.

Summary: A study investigated 68 powdered plant extracts to evaluate their bioactivity profile and identify over 60 important bioactive compounds. The hyphenation method used allowed for the detection and control of active mechanisms in traditional medicines and plant-based foods. The results demonstrated the diverse bioactivity potential of natural foods and their powerful impact on our body's homeostasis.

FRONTIERS IN PHARMACOLOGY (2021)

Article Biochemical Research Methods

Unprecedented sensitivity of the planar yeast estrogen screen by using a spray-on technology

Andreas Schoenborn et al.

JOURNAL OF CHROMATOGRAPHY A (2017)

Review Biochemical Research Methods

Recent advances and progress in the detection of bisphenol A

Fengxia Sun et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2016)

Article Biochemical Research Methods

Investigation on fragmentation pathways of bisphenols by using electrospray ionization Orbitrap mass spectrometry

Hongzhi Zhao et al.

RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2016)

Article Biochemical Research Methods

Monitoring bisphenol A and estrogenic chemicals in thermal paper with yeast-based bioreporter assay

Johanna Rajasarkka et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2014)

Article Chemistry, Analytical

Liquid Chromatography-Bioassay-Mass Spectrometry for Profiling of Physiologically Active Food

Gertrud E. Morlock et al.

ANALYTICAL CHEMISTRY (2014)

Review Environmental Sciences

Bisphenol A - Sources, toxicity and biotransformation

Jaromir Michalowicz

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2014)

Article Biochemical Research Methods

Sharp-bounded zones link to the effect in planar chromatography-bioassay-mass spectrometry

Ines Klingelhoefer et al.

JOURNAL OF CHROMATOGRAPHY A (2014)

Article Chemistry, Analytical

Characterization of a Bisphenol A Specific Yeast Bioreporter Utilizing the Bisphenol A-Targeted Receptor

Johanna Rajasarkka et al.

ANALYTICAL CHEMISTRY (2013)

Review Chemistry, Analytical

Coupling of planar chromatography to mass spectrometry

Gertrud Morlock et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2010)

Review Biochemical Research Methods

Analytical methods for the determination of bisphenol A in food

Ana Ballesteros-Gomez et al.

JOURNAL OF CHROMATOGRAPHY A (2009)

Review Reproductive Biology

An evaluation of evidence for the carcinogenic activity of bisphenol A

Ruth A. Keri et al.

REPRODUCTIVE TOXICOLOGY (2007)

Article Biophysics

A novel estrogen sensor based on recombinant Arxula adeninivorans cells

T Hahn et al.

BIOSENSORS & BIOELECTRONICS (2006)

Review Environmental Sciences

An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment

FS vom Saal et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2005)