4.7 Article

Highly sensitive detection of microRNA-21 by nitrogen-doped carbon dots-based ratio fluorescent probe via nuclease-assisted rolling circle amplification strategy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemical Research Methods

Red-emission carbon dots as fluorescent on-off-on probe for highly sensitive and selective detection of Cu2+ and glutathione

Gan Ning et al.

Summary: This study establishes a sensitive and selective fluorescent on-off-on strategy for the synchronous detection of Cu2+ and glutathione in aqueous solution. The red carbon dots (R-CDs) used in this strategy show a long fluorescence lifetime and high quantum yield. The R-CDs exhibit a pH-responsive property and have low cytotoxicity. The assay can cover a wide range of Cu2+ and glutathione concentrations with low detection limits.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

Article Chemistry, Analytical

A facile and sensitive ratiometric fluorescent sensor for determination of gallic acid

Qin Tan et al.

Summary: A novel ratiometric fluorescent sensor for gallic acid was developed using carbon dots, CoOOH nanoflakes, and o-phenylenediamine, showing high sensitivity with a linear response range of 2.0-60.0 μmol L-1 and a detection limit of 1.2 μmol L-1. The sensor was successfully applied to detect gallic acid in green tea.

MICROCHEMICAL JOURNAL (2022)

Article Biophysics

Acid-improved DNAzyme-based chemiluminescence miRNA assay coupled with enzyme-free concatenated DNA circuit

Huiran Yang et al.

Summary: In this study, we constructed an acid-improved DNAzyme-based isothermal enzyme-free concatenated DNA circuit for miRNA detection. The method achieved significantly reduced background and improved signal-to-noise ratio through catalyzed hairpin assembly (CHA) and hybridization chain reaction (HCR).

BIOSENSORS & BIOELECTRONICS (2022)

Article Chemistry, Physical

Carbon dots as nanocatalytic medicine for anti-inflammation therapy

Bo Kong et al.

Summary: In this study, biocompatible metal-free carbon dots were prepared using a hydrothermal method. These carbon dots exhibited peroxidase-like, catalase-like, and superoxide dismutase-like activities. Both in vitro and in vivo experiments demonstrated the potential of these carbon dots in efficiently scavenging excessive reactive oxygen species (ROS) and reducing inflammation.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

Article Biophysics

Simultaneous dual-targeted monitoring of breast cancer circulating miRNA via surface-enhanced Raman spectroscopy

Jinyoung Kim et al.

Summary: Breast cancer is a common global cancer, and early detection is crucial for improving the 5-year survival rate. In this study, the combination of seed-mediated grown silver nanopillars and surface-enhanced Raman spectroscopy was used for rapid and sensitive detection of circulating miRNA in breast cancer.

BIOSENSORS & BIOELECTRONICS (2022)

Article Chemistry, Analytical

Highly Efficient Quadruped DNA Walker Guided by Ordered DNA Tracks for Rapid and Ultrasensitive Electrochemical Detection of miRNA-21

Tong Yao et al.

Summary: A smart-designed DNA track, known as long period linear DNA tandem (Lr-DNT), was utilized for orderly and efficient operation of a quadruped DNA walker in constructing an electrochemical biosensor for rapid and ultrasensitive microRNA-21 detection. This strategy not only overcomes the low reaction efficiency and time consumption issues, but also opens up new possibilities for clinical sample analysis and cancer diagnostics.

ANALYTICAL CHEMISTRY (2022)

Article Chemistry, Analytical

Ultrasensitive ratiometric fluorescent probes for Hg(ii) and trypsin activity based on carbon dots and metalloporphyrin via a target recycling amplification strategy

Shan Huang et al.

Summary: An innovative ratiometric fluorescent probe utilizing carbon dots and tetraphenylporphyrin tetrasulfonic acid was developed for Hg(ii) detection and trypsin activity evaluation. The probe demonstrated an inspiring detection limit for Hg2+ and trypsin, providing a new insight for designing metal ion assays and enzymatic activity bioassays.

ANALYST (2022)

Article Nanoscience & Nanotechnology

Polythiophene-Based Carbon Dots for Imaging-Guided Photodynamic Therapy

Shaojing Zhao et al.

Summary: This study developed red fluorescent N,S-doped carbon dots as a potential effective photosensitizer for imaging-guided PDT, with the ability to generate singlet oxygen and accumulate in lysosomes and mitochondria in tumor cells. These carbon dots exhibit excellent biocompatibility, chemostability, and a large Stokes shift, making them promising for cancer therapy.

ACS APPLIED NANO MATERIALS (2021)

Article Chemistry, Physical

Solvothermal synthesis of functionalized carbon dots from amino acid as an eco-friendly corrosion inhibitor for copper in sulfuric acid solution

Yu Zhang et al.

Summary: Novel N-doped carbon dots (N-CDs) were synthesized and investigated for their inhibition performance on copper, showing high suppression efficiency. The interaction between N-CDs and copper substrate, as well as the anticorrosion mechanism, were explored in detail through various techniques. The aim of the study is to explore eco-friendly and efficient corrosion inhibitor materials for metal protection.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

Article Chemistry, Analytical

One-step enzyme-free detection of the miRNA let-7a via twin-stage signal amplification

Jiamei Pu et al.

Summary: miRNAs are crucial in various biological processes and their abnormal expression is associated with cancer and diseases. A new fluorescence sensor has been developed for sensitive detection of let-7a gene with good linear relationship and a low limit of detection.

TALANTA (2021)

Article Chemistry, Multidisciplinary

Biobased Carbon Dots: From Fish Scales to Photocatalysis

Carlotta Campalani et al.

Summary: Carbon dots synthesized from fish scales, rich in carbon, hydrogen, oxygen, and nitrogen, displayed good photocatalytic activity in the photoreduction reaction, compared with conventional nitrogen-doped carbon dots.

NANOMATERIALS (2021)

Article Chemistry, Analytical

Utilization of chromogenic enzyme substrates for signal amplification in multiplexed detection of biomolecules using surface mass spectrometry

Hee-Kyung Na et al.

Summary: The study presents a new strategy for the detection of miRNAs with uniformity over a large area based on signal amplification and mass spectrometry measurements, allowing for high sequence specificity and successful detection of target miRNAs in biological samples. The technique shows advantages in scope, quantification, and throughput, making it a potential tool for clinical diagnosis.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Chemistry, Analytical

Dual-mode biosensor for femtomolar miRNA-155 detection by electrochemiluminescence and adsorptive stripping voltammetry

Yanjie Zheng et al.

Summary: A dual-mode electrochemical biosensor has been developed for the sensitive detection of femtomolar miRNA-155 using electrochemiluminescence (ECL) and adsorptive stripping voltammetry (AdsSV). The sensor demonstrates high selectivity, reproducibility and long-term stability, providing a practical platform for rapid, simple, selective and reliable detection of miRNAs.

MICROCHEMICAL JOURNAL (2021)

Article Biochemical Research Methods

A novel zinc finger protein-based amperometric biosensor for miRNA determination

Eloy Povedano et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2020)

Article Chemistry, Physical

Electrocatalytic performance of carbon dots/palladium nanoparticles composite towards hydrogen evolution reaction in acid medium

Pitchai Chandrasekaran et al.

INTERNATIONAL JOURNAL OF HYDROGEN ENERGY (2020)

Article Chemistry, Multidisciplinary

Ultrasensitive detection of microRNA using a bismuthene-enabled fluorescence quenching biosensor

Tianyu Xue et al.

CHEMICAL COMMUNICATIONS (2020)

Article Chemistry, Physical

Single-step synthesis of highly photoluminescent carbon dots for rapid detection of Hg2+ with excellent sensitivity

Bei-Bei Wang et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

Article Chemistry, Multidisciplinary

Design of Metal-Free Polymer Carbon Dots: A New Class of Room-Temperature Phosphorescent Materials

Songyuan Tao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Biochemical Research Methods

Nicking-enhanced rolling circle amplification for sensitive fluorescent detection of cancer-related microRNAs

Zhihua Gao et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

Circular Dichroism of G-Quadruplex: a Laboratory Experiment for the Study of Topology and Ligand Binding

Josue Carvalho et al.

JOURNAL OF CHEMICAL EDUCATION (2017)

Article Oncology

MicroRNA-21 gene and cancer

Yong Huang et al.

MEDICAL ONCOLOGY (2013)

Article Chemistry, Physical

One-step synthesis of fluorescent carbon nanoparticles by laser irradiation

Sheng-Liang Hu et al.

JOURNAL OF MATERIALS CHEMISTRY (2009)

Review Oncology

Oncomirs - microRNAs with a role in cancer

A Esquela-Kerscher et al.

NATURE REVIEWS CANCER (2006)

Article Biochemical Research Methods

Microarray-based, high-throughput gene expression profiling of microRNAs

PT Nelson et al.

NATURE METHODS (2004)

Article Chemistry, Multidisciplinary

Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments

XY Xu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)