Cognitive Function in Patients with Chronic Respiratory Failure: Effect of Treatment with Home Noninvasive Ventilation

Article Respiratory System

Short-term cognitive loading deteriorates breathing pattern and gas exchange in adult patients with congenital central hypoventilation syndrome

Jessica Taytard et al.

Summary: This study found that cognitive tasks induced hypoxia in adult CCHS patients during unassisted breathing, but not under ventilatory support. Therefore, considering the use of ventilatory support during mental tasks in CCHS patients is justified to avoid repeated episodes of hypoxia.

ERJ OPEN RESEARCH (2023)

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Article Respiratory System

Cost-effectiveness of outpatient versus inpatient non-invasive ventilation setup in obesity hypoventilation syndrome: the OPIP trial

Patrick Brian Murphy et al.

Summary: A clinical trial showed that there was no difference in the medium-term cost-effectiveness and clinical effectiveness between outpatient and inpatient NIV setup for patients with obesity hypoventilation syndrome. The choice of home NIV setup strategy can be based on local resource demand and patient and clinician preference.

THORAX (2023)

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Letter Critical Care Medicine

Continuous Positive Airway Pressure for Cognition in Sleep Apnea and Mild Cognitive Impairment: A Pilot Randomized Crossover Clinical Trial

Camilla M. Hoyos et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2022)

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Article Clinical Neurology

Contribution of hypercapnia to cognitive impairment in severe sleep-disordered breathing

Andrew E. Beaudin et al.

Summary: This study investigated the impact of hypercapnia on cognitive function in severe sleep-disordered breathing (OSA accompanied by hypoventilation). The results showed that awake hypoventilation is associated with greater deficits in cognitive function in patients with severe sleep-disordered breathing.

JOURNAL OF CLINICAL SLEEP MEDICINE (2022)

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Letter Critical Care Medicine

Continuous Positive Airway Pressure Restores Declarative Memory Deficit in Obstructive Sleep Apnea

Ina E. Djonlagic et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

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Article Respiratory System

Cognitive Function in a Sleep Clinic Cohort of Patients with Obstructive Sleep Apnea

Andrew E. Beaudin et al.

Summary: The prevalence of mild cognitive impairment (MCI) is high in patients referred to sleep clinics for obstructive sleep apnea (OSA), especially among older males with moderate to severe OSA and vascular comorbidities. Moderate to severe OSA is an independent risk factor for MCI, with higher odds for cognitive impairment compared to patients with no OSA.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2021)

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Article Rehabilitation