4.4 Article

Recovery from olfactory and gustatory dysfunction following COVID-19 acquired during Omicron BA.1 wave in Italy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Otorhinolaryngology

The taste of the pandemic-contemporary review on the current state of research on gustation in coronavirus disease 2019 (COVID-19)

Constantin A. Hintschich et al.

Summary: Subjective impairment of taste is a common symptom of COVID-19, reported in around 50% of cases, but psychophysical testing shows a lower prevalence of 26% due to misinterpretation of olfactory dysfunction. Researchers hypothesize that COVID-19-related hyposmia may contribute to the decrease in gustatory function, requiring further investigation.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2022)

Article Biology

The Effects of Persistent Olfactory and Gustatory Dysfunctions on Quality of Life in Long-COVID-19 Patients

Luigi Angelo Vaira et al.

Summary: Persistent olfactory and gustatory dysfunctions are common symptoms of long-COVID-19 syndrome and significantly impact the mental health component of patients' quality of life.

LIFE-BASEL (2022)

Article Medicine, General & Internal

Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study

Cristina Menni et al.

Summary: This study investigated the differences in symptom prevalence, risk of hospital admission, and symptom duration between omicron and delta variants of the SARS-CoV-2 virus. The study found that loss of smell was less common in omicron infections, sore throat was more common, and the rate of hospital admission was lower.

LANCET (2022)

Article Immunology

Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection

Salma Sheikh-Mohamed et al.

Summary: Although SARS-CoV-2 mainly infects the upper respiratory tract, little is known about the antibodies generated in the oral cavity in response to COVID-19 vaccination. This study found that most participants had detectable antibodies in their saliva after the first dose of mRNA vaccine. The second dose boosted the IgG response but had little effect on the IgA response. Participants with lower levels of vaccine-induced IgA were more likely to experience breakthrough infections.

MUCOSAL IMMUNOLOGY (2022)

Article Otorhinolaryngology

Coronavirus disease 2019 (COVID-19)-related smell and taste impairment with widespread diffusion of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) Omicron variant

Paolo Boscolo-Rizzo et al.

Summary: The prevalence and severity of COVID-19-associated smell and taste dysfunction has significantly decreased with the advent of the Omicron variant but it still remains above 30%.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2022)

Review Biotechnology & Applied Microbiology

OMICRON: Virology, immunopathogenesis, and laboratory diagnosis

Mahsa Bazargan et al.

Summary: This article provides an overview of the biological and immunopathological properties of Omicron and its subvariants, clinical signs and symptoms, Omicron and pediatrics, vaccines against Omicron, re-infection with Omicron, diagnostic approaches, and specific challenges in controlling and managing the rapid global spread of this variant.

JOURNAL OF GENE MEDICINE (2022)

Article Multidisciplinary Sciences

SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

Federico Armando et al.

Summary: This study compares virus spread and pathology in Syrian golden hamsters infected with different variants of SARS-CoV-2 and finds that the Omicron variant causes milder pathology.

NATURE COMMUNICATIONS (2022)

Article Biology

COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)

Wan Yang et al.

Summary: Researchers have used a model-inference system to reconstruct the transmission dynamics of SARS-CoV-2 in South Africa and estimate key epidemiological data for each province. The model has been validated against independent data and can predict future pandemic trajectories. These findings provide insights into the transmission and impact of SARS-CoV-2 variants and inform future public health planning.
Letter Otorhinolaryngology

Two-Year Prevalence and Recovery Rate of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19

Paolo Boscolo-Rizzo et al.

Summary: This cohort study aimed to estimate the 2-year prevalence and recovery rate of smell or taste dysfunction in patients with mildly symptomatic COVID-19.

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY (2022)

Article Cell Biology

Supporting Cells of the Human Olfactory Epithelium Co-Express the Lipid Scramblase TMEM16F and ACE2 and May Cause Smell Loss by SARS-CoV-2 Spike-Induced Syncytia

Andres Hernandez-Clavijo et al.

Summary: This study found that ACE2 and TMEM16F are co-expressed in non-neuronal supporting cells of the human olfactory epithelium, indicating a potential role of syncytia formation in COVID-19 smell loss.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2022)

Article Microbiology

Psychophysical Evaluation of the Olfactory Function: European Multicenter Study on 774 COVID-19 Patients

Luigi Angelo Vaira et al.

Summary: Objective evaluation of olfactory function in COVID-19 patients is challenging due to logistical and safety issues. Psychophysical tests provide more accurate results than patient self-reports. Olfactory disturbances appear to be largely independent of epidemiological and clinical characteristics.

PATHOGENS (2021)

Article Behavioral Sciences

Six-Month Psychophysical Evaluation of Olfactory Dysfunction in Patients with COVID-19

Paolo Boscolo-Rizzo et al.

Summary: This study found that as the time since virus infection increases, olfactory dysfunction becomes more common among patients, with a high percentage showing persistent dysfunction despite most patients subjectively reporting normal smell.

CHEMICAL SENSES (2021)

Article Immunology

Nasal and Salivary Mucosal Humoral Immune Response Elicited by mRNA BNT162b2 COVID-19 Vaccine Compared to SARS-CoV-2 Natural Infection

Mariapia Guerrieri et al.

Summary: The study found that mRNA COVID-19 vaccine induces specific immune responses in nasal and salivary secretions against SARS-CoV-2, with stronger effects observed after the second dose of the vaccine. This suggests that mucosal antibody assays could potentially be used for non-invasive monitoring of vaccine-induced protection against viral infection.

VACCINES (2021)

Article Clinical Neurology

Predictive factors of smell recovery in a clinical series of 288 coronavirus disease 2019 patients with olfactory dysfunction

Sven Saussez et al.

Summary: No clinical markers were found to predict the evolution of olfactory dysfunction (OD) at 60 days. Patients with poor olfactory outcome at 60 days had lower levels of salivary and nasal antibodies, suggesting a role for local immune responses in the persistence of COVID-19 related OD.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

Article Behavioral Sciences

Six-Month Psychophysical Evaluation of Olfactory Dysfunction in Patients with COVID-19

Paolo Boscolo-Rizzo et al.

Summary: This study prospectively assessed the 6-month prevalence of olfactory dysfunction in subjects with mild-to-moderate COVID-19. Despite most patients reporting a subjectively normal sense of smell, a high percentage of persistent smell dysfunction was observed at 6 months, highlighting a significant long-term rate of smell alteration in patients with previous SARS-CoV-2 infection.

CHEMICAL SENSES (2021)

Article Dentistry, Oral Surgery & Medicine

Oral adverse effects of drugs: Taste disorders

Willem Maria Hubertus Rademacher et al.

ORAL DISEASES (2020)

Article Multidisciplinary Sciences

Structure of the secretory immunoglobulin A core

Nikit Kumar et al.

SCIENCE (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19)

Kunwei Li et al.

EUROPEAN RADIOLOGY (2020)

Article Otorhinolaryngology

Objective evaluation of anosmia and ageusia in COVID-19 patients: Single-center experience on 72 cases

Luigi Angelo Vaira et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2020)

Article Medicine, General & Internal

Clinical and epidemiological characteristics of 1420 European patients with mild-to-moderate coronavirus disease 2019

Jerome R. Lechien et al.

JOURNAL OF INTERNAL MEDICINE (2020)

Article Otorhinolaryngology

Evolution of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19

Paolo Boscolo-Rizzo et al.

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY (2020)