EAACI task force report: A consensus protocol for the basophil activation test for collaboration and external quality assurance

Summary: The basophil activation test (BAT) measures the degree of degranulation of basophils following stimulation with allergen, and it can be used as a more specific diagnostic tool for allergic diseases. Clinical application of BAT requires clinical validation, quality assurance, and efforts are ongoing to establish a platform for laboratories to ensure reproducibility and reliability of results.

Summary: Recent clinical trials have shown the effectiveness of basophil activation testing in diagnosing and managing food allergies, with BAT being identified as a biomarker of tolerance. Despite its potential, limitations of BAT need to be addressed for wider adoption.