期刊
AESTHETIC PLASTIC SURGERY
卷 -, 期 -, 页码 -出版社
SPRINGER
DOI: 10.1007/s00266-023-03441-9
关键词
Rhinoplasty; Tranexamic acid; Blood loss; Edema; Ecchymosis
类别
The aim of this study was to assess the effect of local injection of tranexamic acid (TXA) on bleeding, edema, and ecchymosis during and after primary rhinoplasty. The results showed that TXA injection significantly reduced intraoperative bleeding and postoperative edema and ecchymosis without any side effects or complications.
Background and Aims The purpose of this study was assessing the effect of local injection of tranexamic acid (TXA) on the amount of bleeding during the primary rhinoplasty and edema and ecchymosis following the surgery.Methods In this randomized clinical trial, 50 patients applying for primary rhinoplasty were divided into two groups of intervention and observation. In the intervention group, 10 mg/kg of TXA was injected locally to the operation field. In the observation group, no medicine was injected. The same anesthesia technique was used during the operation for all the patients. Age, sex, blood pressure, bleeding amount during the operation, the amount of edema and ecchymosis on the first and seventh day after the surgery were noted. The data were analyzed by the SPSS software version 24 and using descriptive statistics of frequency and percentage of frequency and Fisher and Mann-Whitney's exact statistical tests.Results Our results showed that there was a significant difference between the amounts of bleeding during the surgery between two groups (P-value < 0.001). Also, the postoperative edema on the first and seventh day in intervention group was less than the observation group (P-value < 0.001). There were no complications during the surgery and in the follow-up of the patients.Conclusion We revealed that local injection of TXA during the rhinoplasty procedure and decreased the intraoperative bleeding and postoperative ecchymosis and edema without any side effects and complications.
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