4.8 Article

Bioinspired Intervertebral Disc with Multidirectional Stiffness Prepared via Multimaterial Additive Manufacturing

期刊

ADVANCED FUNCTIONAL MATERIALS
卷 -, 期 -, 页码 -

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.202300298

关键词

additive manufacturing; artificial total disc replacement; bioinspired designs; multidirectional stiffness; multimaterials

向作者/读者索取更多资源

Degenerative disc disease (DDD) is a global public health issue that affects patient health and quality of life. Artificial total disc replacement (A-TDR) is an effective method for treating symptomatic DDD, but current devices lack the ability to replicate the multidirectional stiffness of natural intervertebral discs (IVDs). This study develops a bioinspired intervertebral disc (BIVD-L) that reproduces the multidirectional stiffness needed for physiological kinematic behaviors, providing new insights for the design of A-TDR devices.
Degenerative disc disease (DDD) has become a significant public health issue worldwide. This can result in loss of spinal function affecting patient health and quality of life. Artificial total disc replacement (A-TDR) is an effective approach for treating symptomatic DDD that compensates for lost functionality and helps patients perform daily activities. However, because current A-TDR devices lack the unique structure and material characteristics of natural intervertebral discs (IVDs), they fail to replicate the multidirectional stiffness needed to match physiological motions and characterize anisotropic behavior. It is still unclear how the multidirectional stiffness of the disc is affected by structural parameters and material characteristics. Herein, a bioinspired intervertebral disc (BIVD-L) based on a representative human lumbar segment is developed. The proposed BIVD-L reproduces the multidirectional stiffness needed for the most common physiological kinematic behaviors. The results demonstrate that the multidirectional stiffness of the BIVD-L can be regulated by structural and material parameters. The results of this research deepen knowledge of the biomechanical behavior of the human lumbar disc and may provide new inspirations for the design and fabrication of A-TDR devices for both engineering and functional applications.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据