4.8 Review

Nanomaterials Solutions for Contraception: Concerns, Advances, and Prospects

期刊

ACS NANO
卷 17, 期 21, 页码 20753-20775

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acsnano.3c04366

关键词

nanomaterials solutions; organic; inorganic; nonmetal; drug delivery; photothermal; magnetic hyperthermia; female and male contraceptives; nanotechnologies

向作者/读者索取更多资源

Nanomaterial solutions offer safer, more controllable, and effective approaches for contraception, meeting specific needs of individuals at different reproductive stages. This review summarizes the working mechanisms, clinical concerns, merits, and demerits of nanomaterial solutions for female and male contraception, as well as the nanomaterials adopted in contraceptive applications. Nanomaterials have the potential to replace conventional materials for contraception in the future.
Preventing unintentional pregnancy is one of the goals of a global public health policy to minimize effects on individuals, families, and society. Various contraceptive formulations with high effectiveness and acceptance, including intrauterine devices, hormonal patches for females, and condoms and vasectomy for males, have been developed and adopted over the last decades. However, distinct breakthroughs of contraceptive techniques have not yet been achieved, while the associated long-term adverse effects are insurmountable, such as endocrine system disorder along with hormone administration, invasive ligation, and slowly restored fertility after removal of intrauterine devices. Spurred by developments of nanomaterials and bionanotechnologies, advanced contraceptives could be fulfilled via nanomaterial solutions with much safer and more controllable and effective approaches to meet various and specific needs for women and men at different reproductive stages. Nanomedicine techniques have been extended to develop contraceptive methods, such as the targeted drug delivery and controlled release of hormone using nanocarriers for females and physical stimulation assisted vasectomy using functional nanomaterials via photothermal treatment or magnetic hyperthermia for males. Nanomaterial solutions for advanced contraceptives offer significantly improved biosafety, noninvasive administration, and controllable reversibility. This review summarizes the nanomaterial solutions to female and male contraceptives including the working mechanisms, clinical concerns, and their merits and demerits. This work also reviewed the nanomaterials that have been adopted in contraceptive applications. In addition, we further discuss safety considerations and future perspectives of nanomaterials in nanostrategy development for next-generation contraceptives. We expect that nanomaterials would potentially replace conventional materials for contraception in the near future.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据