☆ 4.8 Article

Delivery of Small-Molecule Drugs and Protein Drugs by Injectable Acid-Responsive Self-Assembled COF Hydrogels for Combinatorial Lung Cancer Treatment

ACS APPLIED MATERIALS & INTERFACES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Multidisciplinary

Hierarchically Structured Molecularly Imprinted Nanotransducers for Truncated HER2-Targeted Photodynamic Therapy of Therapeutic Antibody-Resistant Breast Cancer

Zikuan Gu et al.

Summary: Antibodies have been widely used for clinical treatment of various diseases, particularly cancers. However, cancer cells often develop resistance to therapeutic antibodies due to mutations, leading to difficulties in their development. This study introduces a strategy called molecularly imprinted nanotransducer (MINT) for targeted photodynamic therapy (PDT) of mutated cancers. The MINT is a nanocomposite with an upconversion nanoparticle core, a thin layer of molecularly imprinted polymer shell, and a photosensitizer on the surface. It has been shown to specifically target cancer cells and effectively kill them through light irradiation.

ACS NANO (2023)

添加到收藏夹

Review Engineering, Biomedical

Emerging albumin hydrogels as personalized biomaterials

Fanhui Kong et al.

Summary: Developing biomaterials-based tissue engineering scaffolds using albumin as a sustainable and personalized hydrogel is considered urgent and appealing. Despite the abundance of albumin as a protein and its potential biological applications, it has not been extensively explored as a scaffold for tissue engineering. This review provides valuable insights into recent progress in albumin-based hydrogels, specifically focusing on production techniques, material characteristics, and biological uses. The article emphasizes that albumin-based scaffolds have the potential to meet current tissue engineering needs and contribute to clinical translation for patient benefit.

ACTA BIOMATERIALIA (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice

Qiu-ju Huang et al.

Summary: The study demonstrates the significant improvement in the properties of FTS by conjugating it with IR783, enhancing its anti-cancer potential and tumor-targeting ability. The conjugate shows superior therapeutic effects in breast cancer cells, increasing drug bioavailability and targeting through various pathways.

ACTA PHARMACOLOGICA SINICA (2022)

添加到收藏夹

Article Chemistry, Applied

The recent research progress and application of nanoparticles and ions supporting by covalent organic frameworks

Yiwen Ma et al.

Summary: Covalent organic frameworks (COFs) show great potential in catalysis, adsorption, and separation due to their large surface area, high crystallinity, tunable pore size, and unique molecular architecture. COFs can serve as ideal supports for unstable small materials like nanoparticles, ions, quantum dots, and single atoms, allowing for stable existence and wide application in various fields. This article presents recent advances in the design and synthesis of COF-supported hybrid materials for various applications and discusses future research directions and prospects for the development of efficient COF-supported hybrids.

MICROPOROUS AND MESOPOROUS MATERIALS (2022)

添加到收藏夹

Article Engineering, Biomedical

Magnetic covalent organic framework nanospheres-based miRNA biosensor for sensitive glioma detection

Dong Liang et al.

Summary: In this study, a fluorescent signal amplified miRNA biosensor was constructed using dispersed magnetic covalent organic framework nanospheres (MCOF) as cores and high-crystalline COF as shells. The biosensor showed sensitive detection of miRNA-182 in different matrixes and could quantify miRNA-182 in serum of glioma patients, suggesting its potential application in sensitive detection and accurate diagnosis/prognosis of glioma.

BIOACTIVE MATERIALS (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Covalent Organic Frameworks as a Biomacromolecule Immobilization Platform for Biomedical and Related Applications

Xinyue Wang et al.

Summary: With the development of the biotherapeutic field, biomacromolecules with definite curative effects and small side effects have become a hot topic in the research and development of new drugs. However, there are technical difficulties in using biomacromolecules as drug candidates, mainly related to drug stability and in vivo transport and delivery. To address these challenges, diverse nanodrug delivery systems have been used to deliver biomacromolecules, offering improved stability, bioavailability, and targeted distribution.

ADVANCED THERAPEUTICS (2022)

添加到收藏夹

Review Nanoscience & Nanotechnology

Characteristic Synthesis of a Covalent Organic Framework and Its Application in Multifunctional Tumor Therapy

Shengnan Zhou et al.

Summary: Covalent organic frameworks (COFs) have unique properties that make them attractive for biomedical applications, such as easy synthesis, porosity, and adjustable biocompatibility. This review summarizes the latest developments of COFs in the biomedical field, focusing on their use in cancer diagnosis and treatment, specific preparation methods, and challenges and prospects in applying COFs to clinical transformation.

ACS APPLIED BIO MATERIALS (2022)

添加到收藏夹

Article Nanoscience & Nanotechnology

Facile Synthesis of a Cubic Porphyrin-Based Covalent Organic Framework for Combined Breast Cancer Therapy

Sainan Liu et al.

Summary: In this research, a cubic porphyrin-based COF named CTP with excellent hydrophilicity was prepared for the first time using a simple method. By linking the porphyrin monomer into the COF, solubility and biocompatibility issues were overcome, and the band gap was narrowed. The resulting CTP showed enhanced sonodynamic effect and photothermal conversion under external irradiation.

ACS APPLIED MATERIALS & INTERFACES (2021)

添加到收藏夹

Review Engineering, Biomedical

Covalent Organic Frameworks for Biomedical Applications

Arezoo Esrafili et al.

Summary: Covalent organic frameworks (COFs) are porous organic polymeric materials with desirable properties like high stability, low density, and large surface area, making them suitable for applications in the energy sector and drug delivery. This review discusses different types of COFs, synthesis methods, and their potential applications in the biomedical field, highlighting the specific advantages that can be utilized for specialized biomedical applications such as immune engineering.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Article Oncology

Combination treatment options for small-cell lung cancer

Nobuyuki Horita et al.

LANCET ONCOLOGY (2021)

添加到收藏夹

Letter Medicine, Research & Experimental

2′,7′-Dichlorofluorescein (DCF) or 2′,7′-dichlorodihydrofluorescein diacetate (DCFH2-DA) to measure reactive oxygen species in erythrocytes

Chander Hans et al.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Article Chemistry, Analytical

Improved detection of reactive oxygen species by DCFH-DA: New insight into self-amplification of fluorescence signal by light irradiation

Daliang Yu et al.

Summary: The study identified factors influencing the detection process of ROS by DCFH-DA and developed a new method with higher stability and sensitivity. A significant increase in fluorescence signal of DCFH-DA solution under light irradiation was observed, leading to the development of a reliable and sensitive ROS detection method. This method successfully detected ROS in HeLa cells induced by H2O2 and plastic nanoparticles, providing new insights into the proportional increase of fluorescence signal under light irradiation.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

添加到收藏夹

Article Engineering, Biomedical

Remodeling extracellular matrix based on functional covalent organic framework to enhance tumor photodynamic therapy

Shi-Bo Wang et al.

BIOMATERIALS (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Covalent Organic Frameworks (COFs) for Cancer Therapeutics

Qun Guan et al.

CHEMISTRY-A EUROPEAN JOURNAL (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Fabricating Covalent Organic Framework Capsules with Commodious Microenvironment for Enzymes

Mingmin Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Glycosylated Covalent Organic Framework Equipped with BODIPY and CaCO3for Synergistic Tumor Therapy

Qun Guan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Covalent Organic Framework-Based Nanocomposite for Synergetic Photo-, Chemodynamic-, and Immunotherapies

Sainan Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹

Article Engineering, Biomedical

Polymer-Covalent Organic Frameworks Composites for Glucose and pH Dual-Responsive Insulin Delivery in Mice

Guiyang Zhang et al.

ADVANCED HEALTHCARE MATERIALS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Covalent Organic Framework Embedded with Magnetic Nanoparticles for MRI and Chemo-Thermotherapy

Farah Benyettou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Materials Science, Biomaterials

Thin platelet-like COF nanocomposites for blood brain barrier transport and inhibition of brain metastasis from renal cancer

Guiyang Zhang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Article Engineering, Biomedical

Water-Responsive Hybrid Nanoparticles Codelivering ICG and DOX Effectively Treat Breast Cancer via Hyperthermia-aided DOX Functionality and Drug Penetration

Xuerong Liu et al.

ADVANCED HEALTHCARE MATERIALS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Jessica L. Wojtaszek et al.

CELL (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Cyanine-Assisted Exfoliation of Covalent Organic Frameworks in Nanocomposites for Highly Efficient Chemo-Photothermal Tumor Therapy

Kui Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Tuning Pore Heterogeneity in Covalent Organic Frameworks for Enhanced Enzyme Accessibility and Resistance against Denaturants

Qi Sun et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent advances in covalent organic frameworks (COFs) as a smart sensing material

Xigui Liu et al.

CHEMICAL SOCIETY REVIEWS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery

Guiyang Zhang et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹

Article Engineering, Biomedical

Bioglass Activated Albumin Hydrogels for Wound Healing

Yanling Zhou et al.

ADVANCED HEALTHCARE MATERIALS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Covalent Organic Frameworks with Chirality Enriched by Biomolecules for Efficient Chiral Separation

Sainan Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

添加到收藏夹

Article Oncology

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers

Katrien Van Roosbroeck et al.

CLINICAL CANCER RESEARCH (2017)

添加到收藏夹

Review Medicine, Research & Experimental

Strategies for Preparing Albumin-based Nanoparticles for Multifunctional Bioimaging and Drug Delivery

Fei-Fei An et al.

THERANOSTICS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery

Hong-Xia Wang et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Covalent organic frameworks (COFs): from design to applications

San-Yuan Ding et al.

CHEMICAL SOCIETY REVIEWS (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Therapeutic Proteins: A to Z

Aykut Ozgur et al.

PROTEIN AND PEPTIDE LETTERS (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Porous, crystalline, covalent organic frameworks

AP Côté et al.

SCIENCE (2005)

添加到收藏夹

Review Biochemistry & Molecular Biology

Cancer chemotherapy - ribonucleases to the rescue

PA Leland et al.

CHEMISTRY & BIOLOGY (2001)

添加到收藏夹

Article Oncology

New guidelines to evaluate the response to treatment in solid tumors

F Duffaud et al.

BULLETIN DU CANCER (2000)

添加到收藏夹

Article Oncology

New guidelines to evaluate the response to treatment in solid Tumors

P Therasse et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.