4.7 Article

Nickel-catalysed synthesis of tetrasubstituted vinyl sulfides from thiocarbamates and internal alkynes

期刊

CHEMICAL COMMUNICATIONS
卷 51, 期 7, 页码 1285-1288

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc09123j

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资金

  1. JST, ACT-C
  2. Ministry of Education, Culture, Sports, Science and Technology, Japan
  3. Asahi Glass Foundation
  4. Japan Society for the Promotion of Science for Young Scientists
  5. Grants-in-Aid for Scientific Research [23350017, 25105729] Funding Source: KAKEN

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The thiocarbamoylation of internal alkynes to produce tetrasubstituted beta-aminocarbonyl vinyl sulfides was demonstrated using a nickel catalyst. This reaction was successful with a wide variety of substituents, and gave the syn-adducts exclusively.

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