期刊
GIANT
卷 13, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.giant.2023.100143
关键词
Colloidosome; Pickering emulsion; Biomimetic; Protocell; Origin of life
Artificial counterparts of living cells that bridge the gap between non-living and living materials have been developed. Cell-sized colloidosomes have been utilized as biomimetic cell models due to their robustness and versatility. This review highlights recent advances in the design of cell-like colloidosomes, which mimic advanced cellular behaviors and possess hierarchical structures and functional units. Potential applications in soft robotics, microreactors, and drug delivery are envisioned.
Synthetic counterparts of living cells (protocells) bridge the gap between the non-living and living world. Cell-sized colloidosomes have been explored as biomimetic cell models due to their wide-ranging building blocks, structural robustness, and facile functionalization. Here we review the recent progresses in the design of cell-like colloidosomes as protocell models to imitate the advanced cellular behaviors. We summarize the methods to develop hierarchical compartments by organizing a range of building blocks (e.g., inorganic, organic and hybrid particles) via Pickering emulsion to form membranous structures that isolate themselves from the external environment. By incorporating functional units (e.g., biomolecules), these colloidosomes are capable of displaying cell-like properties such as metabolism, growth/division, motility, and communication. We envision that the hierarchical structures and versatile functions of innovative colloidosomes will further inspire the design of biomimetic soft matter that may build connections between non-living and living materials, and stimulate potential applications in the fields of soft robotics, microreactors and drug delivery.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据