3.8 Article

Olfactory bulbectomy induces nociceptive alterations associated with gliosis in male rats

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

The ion-coupling mechanism of human excitatory amino acid transporters

Juan C. Canul-Tec et al.

Summary: Excitatory amino acid transporters (EAATs) play a crucial role in maintaining glutamate gradients in the brain for neurotransmission and preventing neuronal death. The study reveals that Ca2+ competes for a conserved Na+ site at the synapse, while H+ stabilizes substrate occlusion. The mechanism involving K+ excludes the transmitter during the transport cycle to prevent its neurotoxic release.

EMBO JOURNAL (2022)

Article Neurosciences

Endogenous μ-opioid receptor activity in the lateral and capsular subdivisions of the right central nucleus of the amygdala prevents chronic postoperative pain

Andrew H. Cooper et al.

Summary: The experiment demonstrated that by intracerebroventricular injection of opioid receptor inhibitors, mechanical hypersensitivity can be reinstated, suggesting that MORs in the capsular subdivision of the right CeA prevent the transition from acute to chronic postoperative pain. Furthermore, it was found that systemic administration of naloxone and naltrexone in LS animals produced different effects compared to naive or sham controls.

JOURNAL OF NEUROSCIENCE RESEARCH (2022)

Article Biochemistry & Molecular Biology

Curcumin induces cortico-hippocampal neuronal reshaping and memory improvements in aged mice

Aldo Efrain Gonzalez-Granillo et al.

Summary: The study shows that chronic curcumin treatment can improve learning and memory, increase synaptic density and dendritic branching, and reduce aging-related damages by regulating the expression of certain proteins.

JOURNAL OF CHEMICAL NEUROANATOMY (2022)

Article Biochemistry & Molecular Biology

Basolateral Amygdala Reactive Microglia May Contribute to Synaptic Impairment and Depressive-Like Behavior in Mice with Bone Cancer Pain

Li Jiang et al.

Summary: Anxiety and depression caused by cancer-related pain can negatively impact quality of life and motivation to survive. This study investigated the role of microglia in mediating depression induced by cancer pain. The findings suggest that the phagocytic function of microglia in the basolateral amygdala may contribute to synaptic loss and depressive behavior in a bone cancer pain model.

NEUROCHEMICAL RESEARCH (2022)

Article Clinical Neurology

Changes in glial gene expression in the prefrontal cortex in relation to major depressive disorder, suicide and psychotic features

Lin Zhang et al.

Summary: This study found different glial alterations in the prefrontal cortex of patients with major depressive disorder, which were associated with suicide behaviors or psychotic features. Certain genes showed differences in expression levels between suicide and psychotic feature patients, providing insights into the pathophysiology of MDD.

JOURNAL OF AFFECTIVE DISORDERS (2021)

Article Neurosciences

Repetitive non-invasive prefrontal stimulation reverses neuropathic pain via neural remodelling in mice

Zheng Gan et al.

Summary: Non-invasive, repetitive direct anodal current transcranial stimulation of the prefrontal cortex exerted long-lasting analgesic effects in mice with neuropathic pain, reversing established allodynia and affecting basal activity and responsiveness of distant areas. The study provides valuable insights into the neural mechanisms of prefrontal tDCS in neuropathic pain, highlighting the potential for non-invasive transcranial stimulation paradigms to achieve pain relief in chronic states.

PROGRESS IN NEUROBIOLOGY (2021)

Article Clinical Neurology

Chronic Stress Alters Astrocyte Morphology in Mouse Prefrontal Cortex

Sierra A. Codeluppi et al.

Summary: Chronic stress exposure induces progressive atrophy of cortical astroglial cells in mice, potentially contributing to maladaptive neuroplastic and behavioral changes associated with stress-related disorders.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2021)

Article Psychiatry

Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats

Kai Xiao et al.

Summary: Running exercise can alleviate symptoms of depression by reducing the number of microglia and inhibiting their activation in the hippocampus, leading to a decrease in neuroinflammation levels and improvement in depressive-like symptoms.

TRANSLATIONAL PSYCHIATRY (2021)

Article Psychiatry

Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model

Roberto Farina Almeida et al.

Summary: This study aimed to investigate the long-term behavioral and neurochemical effects of GUO in a mouse model of depression induced by bilateral bulbectomy (OBX), showing beneficial neurochemical outcomes relevant to counteract depression.

FRONTIERS IN PSYCHIATRY (2021)

Article Clinical Neurology

Caffeine prevents neurodegeneration and behavioral alterations in a mice model of agitated depression

Daniele Guilhermano Machado et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2020)

Article Cell Biology

Aging and sex: Impact on microglia phagocytosis

Natalia Yanguas-Casas et al.

AGING CELL (2020)

Article Gastroenterology & Hepatology

Inhibition of Microglial Activation in the Amygdala Reverses Stress-Induced Abdominal Pain in the Male Rat

Tian Yuan et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2020)

Review Biochemistry & Molecular Biology

OBscure but not OBsolete: Perturbations of the frontal cortex in common between rodent olfactory bulbectomy model and major depression

Ramamoorthy Rajkumar et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2018)

Article Clinical Neurology

Olfactory bulbectomy in mice triggers transient and long-lasting behavioral impairments and biochemical hippocampal disturbances

Roberto Farina de Almeida et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2017)

Review Behavioral Sciences

The olfactory bulbectomized rat as a model of depression: The hippocampal pathway

J. C. Morales-Medina et al.

BEHAVIOURAL BRAIN RESEARCH (2017)

Review Neurosciences

Integrating neuroimmune systems in the neurobiology of depression

Eric S. Wohleb et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Review Neurosciences

Neuroplasticity Underlying the Comorbidity of Pain and Depression

Lisa Doan et al.

NEURAL PLASTICITY (2015)

Article Biochemistry & Molecular Biology

Olfactory bulbectomy induces neuronal rearrangement in the entorhinal cortex in the rat

Julio Cesar Morales-Medina et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2013)

Article Neurosciences

Microglia Are Essential to Masculinization of Brain and Behavior

Kathryn M. Lenz et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Astrocytic Hypertrophy in Anterior Cingulate White Matter of Depressed Suicides

Susana G. Torres-Platas et al.

NEUROPSYCHOPHARMACOLOGY (2011)

Review Physiology

Physiology of Microglia

Helmut Kettenmann et al.

PHYSIOLOGICAL REVIEWS (2011)

Article Neurosciences

Activation of Metabotropic Glutamate Receptor 5 in the Amygdala Modulates Pain-Like Behavior

Benedict J. Kolber et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Biochemistry & Molecular Biology

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

Carol Kilkenny et al.

PLOS BIOLOGY (2010)

Article Neurosciences

Hemispheric Lateralization of Pain Processing by Amygdala Neurons

Guangchen Ji et al.

JOURNAL OF NEUROPHYSIOLOGY (2009)

Article Neurosciences

Synaptic islands defined by the territory of a single astrocyte

Michael M. Halassa et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Neurosciences

Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception

Yarimar Carrasquillo et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Neurosciences

Cellular changes in the postmortem hippocampus in major depression

CA Stockmeier et al.

BIOLOGICAL PSYCHIATRY (2004)