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Article
Mathematical & Computational Biology
Olumuyiwa James Peter et al.
Summary: This study formulates and analyzes an eight-dimensional ordinary differential equation model for COVID-19, taking into account the first and second dose of vaccination. The model is calibrated using the least-squares method and a global sensitivity analysis is performed to identify influential parameters. The results show that adhering to preventive measures and increasing vaccination rates significantly reduce the spread of the disease and the burden on the population.
ACTA BIOTHEORETICA
(2023)
Review
Infectious Diseases
Thibault Fiolet et al.
Summary: Overall, COVID-19 vaccines have high efficacy against the original strain and variants of concern, with rare serious adverse events. However, prices vary significantly for different vaccines.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Article
Medicine, General & Internal
Sue Ann Costa Clemens et al.
Summary: A study was conducted to evaluate the safety and immunogenicity of a third dose of heterologous or homologous vaccines in Brazilian adults who had previously received two doses of CoronaVac. The results showed that a third dose of heterologous vaccines (recombinant adenoviral vectored vaccine or mRNA vaccine) significantly increased immune responses and could improve protection against infection.
Article
Multidisciplinary Sciences
Camilla Cattaneo et al.
Summary: The present study aimed to evaluate smell and taste functions in hospitalized COVID-19 patients and compare the results with a healthy control group. The study found a significant impairment of olfactory and gustatory functions in COVID-19 patients, with male patients suffering from more severe respiratory failure showing more evident gustatory and olfactory impairments.
SCIENTIFIC REPORTS
(2022)
Article
Materials Science, Multidisciplinary
Anip Kumar Paul et al.
Summary: This study examines the COVID-19 situation in Bangladesh and proposes a double-dose vaccination strategy to control the outbreak. Through qualitative analysis and numerical simulations, it is found that a full dose vaccination program can effectively reduce the number of cases and potentially eliminate the virus from the community.
RESULTS IN PHYSICS
(2022)
Article
Computer Science, Artificial Intelligence
Abeer D. Algarni et al.
Summary: The discovery and analysis of a new mathematical model provides insights into the effectiveness of COVID-19 vaccines and their impact on reducing transmission rates, aiding governments in formulating vaccination strategies.
PEERJ COMPUTER SCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Elena Aruffo et al.
Summary: The study showed that targeting the elderly population with high vaccine coverage is crucial, and focusing on the 20-39 and 40-59 age groups with at least 70% first-dose coverage by mid-June 2021 is necessary to minimize the risk of resurgence when lifting NPIs. An optimistic vaccination scenario with 70% coverage by mid-June and delaying reopening can significantly reduce case counts and severe outcomes by the end of 2021.
Article
Physics, Multidisciplinary
Sadia Arshad et al.
Summary: To achieve the goal of ceasing the spread of COVID-19 entirely, understanding the dynamical behavior of the virus proliferation is crucial. Mathematical modeling can provide a valuable and economical way to comprehend the key factors involved in the spread of the virus, especially when analyzing the impact of vaccination. In this article, a fractional order epidemic model is presented, and numerical methods are used to study and simulate the COVID-19 model. The results suggest that reducing the contact rate can decrease the number of cases if the population is not fully vaccinated, but increasing the vaccination rate is a better solution to reduce social distancing and lockdowns' negative impact.
EUROPEAN PHYSICAL JOURNAL PLUS
(2022)
Article
Multidisciplinary Sciences
Tanatorn Intarapanya et al.
Summary: This research investigates the relationship between the spread of COVID-19 and immigration policies, developing a mathematical model to simulate the spread of the disease under various immigration conditions. The results of the experiments demonstrate that increasing control measures on undocumented immigration across natural borders can effectively control the spread of the virus.
Review
Microbiology
Ben Hu et al.
Summary: This review summarizes the research progress on SARS-CoV-2 and COVID-19, including virology characteristics, pathogenesis, and recent advances in treatment methods. Furthermore, it discusses in detail the potential wildlife hosts and zoonotic origin of this emerging virus.
NATURE REVIEWS MICROBIOLOGY
(2021)
Article
Medicine, General & Internal
Merryn Voysey et al.
Summary: The ChAdOx1 nCoV-19 vaccine has been shown to have an acceptable safety profile and effectiveness against symptomatic COVID-19, with higher efficacy observed in the group that received a low dose followed by a standard dose.
Article
Immunology
Thi Nhu Mai Tran et al.
Summary: The development of the SARS-CoV-2 vaccine candidate Nanocovax, based on recombinant protein production of the S protein, induced high levels of specific IgG antibodies and provided protection against upper respiratory tract infection in animal models, demonstrating safety and efficacy.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Mathematics
Hennie Husniah et al.
Summary: A mathematical model considering convalescent plasma transfusion (CPT) was developed to analyze the effects of different application rates on lowering the number of infectious individuals. Standard procedures in mathematical epidemiology were used to analyze the model, showing that the use of CPT resulted in a lower peak of infection cases and other epidemiological measures.
Article
Biochemistry & Molecular Biology
Giulia Giordano et al.
Summary: This study combines multiple models to predict the spread and consequences of COVID-19 cases, finding that non-pharmaceutical interventions have a greater impact on the epidemic evolution. Using a data-based model, different scenarios of vaccine rollouts and interventions are proposed to assess their impact on the pandemic.
Review
Microbiology
Nancy H. L. Leung
Summary: Respiratory virus infections cause a significant global health problem, with different viruses varying in transmission modes and transmissibility. Understanding the relative contributions of different transmission modes is crucial for guiding the effectiveness of non-pharmaceutical interventions.
NATURE REVIEWS MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Mohammadali Dashtbali et al.
Summary: The study introduced two compartmental models to analyze individual behavior in spreading and controlling the COVID-19 epidemic. The comparison showed that the second model provided a better fit to the daily infected cases from Egypt, Belgium, Japan, Nigeria, Italy, and Germany. Furthermore, a vaccinated term was added to the model to predict how vaccination could control the epidemic.
SCIENTIFIC REPORTS
(2021)
Article
Public, Environmental & Occupational Health
David K. Shay et al.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2021)
Article
Mathematical & Computational Biology
M. L. Diagne et al.
Summary: A mathematical model was developed to analyze the COVID-19 transmission mechanism and the impact of therapeutic measures, showing globally stable disease-free and endemic equilibriums when R-0(v) is less or greater than unity. Findings also revealed the critical vaccination threshold dependent on vaccine efficacy and highlighted the most impactful parameters through sensitivity analysis.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
(2021)
Article
Biology
Manuel Adrian Acuna-Zegarra et al.
Summary: After over a year into the COVID-19 pandemic, global deaths have surpassed two million, and while vaccines have shown progress, cases continue to rise with uncertainties around vaccine-induced and natural immunity. With vaccine supply shortages leading to delays in some countries, logistical, economic, and political factors present challenges in developing vaccination policies.
MATHEMATICAL BIOSCIENCES
(2021)
Article
Immunology
Manish Sadarangani et al.
Summary: Most COVID-19 vaccines aim to induce immune responses, particularly neutralizing antibodies (NAbs), against the spike protein of the virus. mRNA vaccines have shown efficacy after just one dose, while adenovirus vaccines elicit polyfunctional antibodies and strong T cell responses. These findings suggest that protection may not solely rely on NAbs but also involve other immune effector mechanisms.
NATURE REVIEWS IMMUNOLOGY
(2021)
Article
Medicine, General & Internal
Chaolin Huang et al.
Article
Multidisciplinary Sciences
Peng Zhou et al.
Article
Mathematics, Interdisciplinary Applications
M. Higazy
CHAOS SOLITONS & FRACTALS
(2020)
Article
Multidisciplinary Sciences
Din Prathumwan et al.
Review
Public, Environmental & Occupational Health
Basavraj Nagoba et al.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2020)
Article
Automation & Control Systems
Marc Bodson
IEEE CONTROL SYSTEMS MAGAZINE
(2020)
Article
Biology
Nakul Chitnis et al.
BULLETIN OF MATHEMATICAL BIOLOGY
(2008)
Article
Biology
P van den Driessche et al.
MATHEMATICAL BIOSCIENCES
(2002)
