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Article
Engineering, Electrical & Electronic
Guoqiang Li et al.
Summary: Three-dimensional liquid metal structures can be created using ductile gallium-indium alloy wires encapsulated in an elastomer and heated to recover their fluidity. This technology overcomes the challenge of building complex circuits with liquid metals and has potential applications in soft and stretchable electronics. The technique allows the fabrication of high-sensitivity strain sensors, three-dimensional interconnect arches for LED arrays, and wearable sensors and flexible circuit boards for motion monitoring.
NATURE ELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Muzhi Jiang et al.
Summary: By injecting liquid metal into living plants, electronic components such as resistors, inductors, and capacitors can be successfully fabricated, enabling real-time monitoring of plant physiological signals and endowing plants with diverse electronic capabilities. The resulting injectable electrodes exhibit outstanding signal capture capability and anti-interference characteristics, injectable resistance and capacitance sensors provide useful ways for plant monitoring, and injectable capacitance sensors offer access to plant interior information. Additionally, antennas with variable characteristics are manufactured and evaluated in situ in living plants, demonstrating the potential of plant injectable electronics. This principle signifies a paradigm shift in combining plants and electronics and opens up possibilities for further research in plant electrophysiology, electronic plants, and plant robots.
Review
Engineering, Biomedical
Sen Chen et al.
Summary: This review provides a comprehensive summary of the current knowledge on liquid metal toxicology and biocompatibility, focusing on Ga and Bi-based liquid metals. It discusses the challenges and suggests further investigation to clarify toxicological mechanisms and strategies to avoid adverse effects. The review aims to promote the healthy and sustainable development of liquid metal-based materials, particularly in healthcare applications.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Automation & Control Systems
Sen Chen et al.
Summary: This review presents an overview of the typical progress in liquid metal smart materials and their robotic response behaviors, with a focus on the concept of smart composite systems consisting of liquid metals and synergistic substances. The response behaviors of liquid metal smart materials under the actions of external factors are examined and the smart properties occurring during these responses are identified. Soft actuators, control systems, and robots based on liquid metal smart materials are summarized and potential directions and challenges are outlined.
ADVANCED INTELLIGENT SYSTEMS
(2023)
Article
Engineering, Biomedical
Ruixue Liu et al.
Summary: This study presents a nanotechnology strategy for tumor radiosensitization using nanosized gallium-indium eutectic alloys as a radiosensitizer. The functionalized nanoparticles show low cytotoxicity, good biocompatibility, and in-situ gel formation in the tumor microenvironment. Due to their metallic nature, they can increase the generation of reactive oxygen species under X-ray irradiation, leading to enhanced tumor inhibition. Additionally, these nanoparticles also serve as imaging contrast agents for computed tomography and photoacoustic tomography.
ADVANCED HEALTHCARE MATERIALS
(2022)
Review
Materials Science, Biomaterials
Wenwen Gao et al.
Summary: Liquid metals offer unique properties that make them promising biomaterials for biomedical imaging. This paper reviews the preparation, characteristics, and toxicity analysis of liquid metal-based biomaterials. Additionally, it presents in-depth discussions on the applications of liquid metals in various imaging techniques and explores the challenges and opportunities in medical imaging.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Biophysics
Rouqiao Zheng et al.
Summary: Manganese-based Metal-organic Frameworks (Mn-MOFs) have significant potential in biomedical applications, especially in imaging, anti-tumor therapy, and antimicrobial applications. The low toxicity, oxidative ability, and biocompatibility of Mn-MOFs make them highly desirable in medical field. Manganese complexes also show promising prospects in drug targeting.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Engineering, Biomedical
Kewang Nan et al.
Summary: An inexpensive catheter-like device made of a piezoresistive elastic silicone-liquid-metal composite has been developed for measuring the tone and contractile patterns of the gastrointestinal tract. The device performs comparably to commercial devices and can be used in low-resource settings.
NATURE BIOMEDICAL ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Wonbeom Lee et al.
Summary: An elastic printed circuit board (E-PCB) is a conductive framework used for the assembly of stretchable electronics. This study presents a method using a liquid metal particle network (LMPNet) as an elastic conductor, which satisfies all the requirements for E-PCBs. The LMPNet enables the fabrication of high-density E-PCBs, allowing the integration of numerous electronic components to create highly stretchable skin electronics.
Review
Pharmacology & Pharmacy
Yana Zeng et al.
Summary: Coordination chemistry plays a vital role in studying the material properties of metal-organic systems. Metal-organic frameworks (MOFs) have attracted significant attention in medical science due to their large surface area, clear pore network, and catalytic performance. Core-shell MOF materials have higher loading rate and better stability compared to traditional MOFs, making them promising for various tumor treatments. This review article discusses the synthesis, structure, and potential applications of core-shell MOF materials in tumor therapy, including chemotherapy, phototherapy, and anti-hypoxia therapy.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Review
Biochemistry & Molecular Biology
Wenfeng Zhang et al.
Summary: This paper reviews the mechanism and antibacterial effect of three typical MOFs in silver-based coordination polymers and discusses the existing shortcomings and future perspectives. The study on Ag-MOFs can provide a better basis for its clinical application and open up a novel strategy for the preparation of more advanced Ag-contained materials with antibacterial characteristics.
Review
Biotechnology & Applied Microbiology
Chun-Chun Qu et al.
Summary: With the indiscriminate use of antibiotics, the hazards caused by drug-resistant bacteria are increasing rapidly. Therefore, it is urgent to develop new non-antibiotic antibacterial drugs. Liquid metal, with excellent biocompatibility and diverse multifunctionalities, has stimulated research on its antibacterial application. This research focuses on gallium (a type of liquid metal) ions disrupting the normal metabolism of iron ions, resulting in the development of several gallium-based antimicrobial agents. In addition, emerging strategies such as physical sterilization and thermal destruction are gaining attention. Unlike traditional antibacterial agents, liquid metal materials bring innovation to the antibacterial field.
BIOENGINEERING-BASEL
(2022)
Review
Chemistry, Inorganic & Nuclear
Jinyi Chen et al.
Summary: Metal-organic frameworks (MOFs), including titanium-based MOFs (Ti-MOFs), have gained significant attention for their wide range of applications. However, the development of MOF materials for biological applications is still an emerging field. This study reviews the recent research progress on Ti-MOFs in therapeutic areas such as antibacterial, oncology, anti-inflammation, and bone injury, providing new directions for further research in the biomedical field.
DALTON TRANSACTIONS
(2022)
Article
Engineering, Biomedical
Nailin Yang et al.
Summary: In this study, a series of core-shell GaIn@Metal heterogeneous nanoparticles were obtained by a simple in-situ reduction method. Among them, the core-shell GaIn@Pt NPs showed significantly improved photothermal conversion efficiency and exhibited good Fenton-like catalytic effect. With PEG modification, these NPs displayed efficient tumor homing and effective NIR II triggered photothermal-chemodynamic synergistic therapy in a mouse tumor model.
Article
Engineering, Biomedical
Zhenhu Guo et al.
Summary: In this study, litchi-shaped heterogeneous gallium indium-gold nanoparticles were successfully prepared and utilized as effective radiosensitizers and photothermal agents for radio-photothermal cancer therapy, showing promising therapeutic effects.
BIOACTIVE MATERIALS
(2021)
Article
Engineering, Biomedical
Tingting Xie et al.
Summary: ICG-Ga NPs, a novel non-antibiotic nanoparticle, demonstrate excellent therapeutic effect against multidrug-resistant bacteria with the synergetic effect of photodynamic therapy and iron metabolism blocking, significantly improving treatment outcomes in cases of liver abscess and keratitis infection. The ultrasmall size allows rapid renal clearance without compromising biocompatibility, indicating potential for clinical treatment of bacterial infections and next-generation antibacterial agents.
BIOACTIVE MATERIALS
(2021)
Review
Engineering, Biomedical
Young-Geun Park et al.
Summary: Liquid metals, known for their excellent stretchability and biocompatibility, are being extensively explored as conductors for wearable healthcare devices, providing crucial support for personal health management.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Biotechnology & Applied Microbiology
Wanjie Xie et al.
Summary: Gallium-based LMPs offer low toxicity, excellent electrical and thermal conductivities, and fluidity at room temperature, making them suitable for a range of therapeutic applications. However, fundamental research on their unique characteristics for therapeutics remains underexplored, while recent advances in their design and implementation show promising potential for drug delivery, cancer treatment, bioimaging, and biosensing.
TRENDS IN BIOTECHNOLOGY
(2021)
Article
Chemistry, Inorganic & Nuclear
Ishita Virmani et al.
JOURNAL OF CLUSTER SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Aaron Elbourne et al.
Review
Multidisciplinary Sciences
Yanguang Cong et al.
JOURNAL OF ADVANCED RESEARCH
(2020)
Editorial Material
Pharmacology & Pharmacy
Michael J. Rybak et al.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
(2020)
Article
Chemistry, Multidisciplinary
Xuyang Sun et al.
ADVANCED FUNCTIONAL MATERIALS
(2020)
Review
Immunology
Michael J. Rybak et al.
CLINICAL INFECTIOUS DISEASES
(2020)
Review
Materials Science, Multidisciplinary
Sen Chen et al.
Article
Multidisciplinary Sciences
Sohn G. Kim et al.
Article
Engineering, Biomedical
Jing-Jing Hu et al.
Article
Chemistry, Applied
Clara Lopez-Iglesias et al.
CARBOHYDRATE POLYMERS
(2019)
Article
Chemistry, Physical
Junjie Yan et al.
Review
Chemistry, Multidisciplinary
Junjie Yan et al.
CHEMICAL SOCIETY REVIEWS
(2018)
Article
Engineering, Biomedical
Xuelin Wang et al.
ADVANCED HEALTHCARE MATERIALS
(2018)
Article
Cell Biology
Christopher H. Goss et al.
SCIENCE TRANSLATIONAL MEDICINE
(2018)
Editorial Material
Biotechnology & Applied Microbiology
Sarah Crunkhorn
NATURE REVIEWS DRUG DISCOVERY
(2018)
Article
Multidisciplinary Sciences
Svetlana A. Chechetka et al.
NATURE COMMUNICATIONS
(2017)
Article
Food Science & Technology
Chris S. Ivanoff et al.
FOOD AND CHEMICAL TOXICOLOGY
(2012)
Article
Infectious Diseases
PC Appelbaum
CLINICAL MICROBIOLOGY AND INFECTION
(2006)
Article
Immunology
SE Cosgrove et al.
CLINICAL INFECTIOUS DISEASES
(2004)
Review
Chemistry, Multidisciplinary
BK Hubbard et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2003)
Article
Chemistry, Medicinal
DL Boger
MEDICINAL RESEARCH REVIEWS
(2001)
Article
Immunology
FC Tenover et al.
EMERGING INFECTIOUS DISEASES
(2001)
Article
Immunology
LB Rice
EMERGING INFECTIOUS DISEASES
(2001)