期刊
BIOENGINEERING-BASEL
卷 10, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/bioengineering10020237
关键词
iPS-derived cardiomyocytes; cardiovascular disease; embryonic stem cells; Wnt signaling; pluripotency
Induced pluripotent stem cells (iPSCs) have gained attention as an ethical alternative to embryonic stem cells (ESCs) and hold promise for the treatment of heart failure through differentiated cardiomyocytes. This paper explores the differentiation process of human iPSC-derived cardiomyocytes and their potential applications, addressing ethical concerns.
Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs). Due to their ability to differentiate into several kinds of cells, including cardiomyocytes, researchers quickly realized the potential for differentiated cardiomyocytes to be used in the treatment of heart failure, a research area with few alternatives. This paper discusses the differentiation process for human iPSC-derived cardiomyocytes and the possible applications of said cells while answering some questions regarding ethical issues.
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