相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review
Immunology
Saurabh Mehandru et al.
Summary: This review examines the underlying pathophysiological mechanisms of post-COVID-19 syndromes, including persistent inflammation, induced autoimmunity, and putative viral reservoirs. The disease is called 'long-haul COVID' or 'post-COVID-19 syndrome', and clinical symptoms include fatigue, dyspnea, and neuropsychiatric syndromes.
Article
Immunology
Miguel Galan et al.
Summary: Long-COVID is a syndrome characterized by persistent symptoms and signs of COVID-19 even after weeks or months of infection. The underlying mechanisms are unclear, but immune dysregulation and certain clinical and demographic factors may contribute to the development of this condition. Accurate diagnostic biomarkers can help improve the management of Long-COVID patients.
FRONTIERS IN IMMUNOLOGY
(2022)
Letter
Respiratory System
Tamara Cruz et al.
Article
Respiratory System
Oriol Sibila et al.
Summary: The study found that about 60% of COVID-19 survivors had reduced DLCO 6 months after discharge, mainly in those over 60 years old, with a history of smoking, hypertension, severe COVID-19 experience, and persistent dyspnea after discharge. In addition, patients with reduced DLCO had higher levels of epithelial and endothelial markers.
RESPIRATORY RESEARCH
(2022)
Article
Medicine, General & Internal
Chaolin Huang et al.
Summary: This study aimed to investigate the long-term health consequences of discharged COVID-19 patients and associated risk factors, particularly disease severity. Patients with more severe illness during hospitalization showed more severe impaired pulmonary diffusion capacities and abnormal chest imaging manifestations, highlighting the need for targeted interventions for long-term recovery.
Article
Multidisciplinary Sciences
Christian Gaebler et al.
Summary: After infection with SARS-CoV-2, antibody levels against the spike protein decrease significantly, but the number of memory B cells remain unchanged, indicating an evolving humoral response at 6.2 months after infection.
Letter
Respiratory System
Oriol Sibila et al.
ARCHIVOS DE BRONCONEUMOLOGIA
(2021)
Review
Biochemistry & Molecular Biology
Ani Nalbandian et al.
Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.
Article
Critical Care Medicine
Woo-Jung Song et al.
Summary: Cough is a common symptom of COVID-19 and can persist for weeks or even months after infection, leading to long-term effects known as post-COVID syndrome. Researchers hypothesize that neurotropic pathways may be responsible for cough hypersensitivity state after SARS-CoV-2 infection, and neuroinflammatory events in the brain could contribute to the development of post-COVID syndrome. There are gaps in understanding the mechanisms of acute and chronic COVID-19 associated cough and post-COVID syndrome, but potential ways to reduce the impact of COVID-19 by controlling cough are being considered.
LANCET RESPIRATORY MEDICINE
(2021)
Article
Multidisciplinary Sciences
Sandra Lopez-Leon et al.
Summary: This study aimed to identify studies assessing the long-term effects of COVID-19, estimating that 80% of infected patients will develop one or more long-term symptoms, with the most common being fatigue, headache, attention disorder, hair loss, and dyspnea.
SCIENTIFIC REPORTS
(2021)
Article
Cell Biology
Michael J. Peluso et al.
Summary: In this study, 70 individuals with PCR-confirmed SARS-CoV-2 infection were longitudinally observed for T cell responses, inflammation markers, antibody levels, and neutralization capacity. The study found that T cell responses remain stable for up to 9 months and that CD4(+) T cell responses in the early stage correlate with the severity of infection. Pre-existing lung disease is independently associated with higher long-term CD8(+) T cell responses, and individuals with PASC showed a more rapid decline in specific CD8(+) T cell responses.
Article
Immunology
Jiufeng Sun et al.
EMERGING INFECTIOUS DISEASES
(2020)
Article
Critical Care Medicine
Brian L. Graham et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2019)
Article
Respiratory System
Brian L. Graham et al.
EUROPEAN RESPIRATORY JOURNAL
(2017)