4.3 Article

In-vitro anticancer activity of green synthesized silver nanoparticles on MCF-7 human breast cancer cells

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2016.03.101

关键词

Green synthesis; Lonicera hypoglauca; Silver NPs; Anticancer; MCF-7

资金

  1. KIOM Undergraduate Research Program - Korea Institute of Oriental Medicine
  2. Dongguk University Research Fund

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In recent years, green synthesis of metallic nanoparticles is a growing area of research because of their potential applications in nanomedicine. In the present study we synthesized silver nanoparticles (silver NPs) from AgNO3 using aqueous extract of Lonicera hypoglauca flower as reducing and capping agents. The synthesized silver NPs were characterized using IJV Vis spectroscopy, FTIR, SEM-ED, TEM and SAED. Silver NPs were found to be significantly toxic to MCF-7 cells via the induction of apoptosis whereas sparing normal immune system (RAW 264.7) cells. (C) 2016 Elsevier B.V. All rights reserved.

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