期刊
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
卷 69, 期 -, 页码 744-750出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2016.07.050
关键词
317L-Cu; Antibacterial; Staphylococcus aureus; Biofilm; Cytotoxicity
资金
- National Natural Science Foundation of China [11332003, 31370949, 81400329]
- National Key Research and Development Program [2016YFC1102305]
- Young Merit Scholars program of the Institute of Metal Research, Chinese Academy of Sciences
- Chongqing Engineering Laboratory in Vascular Implants
- National 111 Plan Base [B06023]
- Public Experiment Center of the State Bioindustrial Base (Chongqing) of China
The present study investigated the antibacterial performance, corrosion resistance and surface properties of antibacterial austenitic 317L-Cu stainless steel (317L-Cu SS). After 4.5 wt% copper was added to 317L stainless steel (317L SS), the new alloy underwent solid solution and aging heat treatment. Fluorescent staining using 4',6-diamidino-2-phenylindole (DAPI) revealed that the 317L-Cu SS showed strong antibacterial efficacy, achieving a 99% inhibition rate of sessile Staphylococcus aureus cells after 5 days. The corrosion data obtained by potentio-dynamic polarization curves indicated that in comparison with 317L SS, the pitting potential and corrosion current density of 317L-Cu slightly decreased due to the addition of Cu. The 317L-Cu SS exhibited no cytotoxicity against zebrafish (Danio rerio) embryos. The experimental results in this study demonstrated that the new alloy has potential applications in medical and daily uses. (C) 2016 Elsevier B.V. All rights reserved.
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