期刊
MATERIALS LETTERS
卷 185, 期 -, 页码 185-188出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2016.08.140
关键词
Biomaterials; Carbon materials; Polymeric composites; Diamond; Imaging
资金
- Australian Research Council [CE14010003, LE140100131, FT110100225]
- ARC Future Fellowship [FT110100225]
- Defence Science Institute
- Australian Research Council [LE140100131, FT110100225] Funding Source: Australian Research Council
For tissue scaffolding, it is desirable for the scaffold to promote growth of the native tissue, before the scaffold is ultimately replaced by tissue. While polycaprolactone (PCL) is a superb scaffold material, it is impossible to non-invasively monitor its degradation. Here, incorporating fluorescent nanodiamonds into PCL, we show sub-dermal fluorescence imaging of PCL. This provides an opportunity to monitor PCL degradation to assess real-time tissue uptake and replacement. Furthermore, nanodiamonds increase the hydrophillicity PCL, and hence may increase tissue uptake rates, opening new applications for PCL (C) 2016 Elsevier B.V. All rights reserved.
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