Biomedical Applications of Blow-Spun Coatings, Mats, and Scaffolds-A Mini-Review

Human tissues and disease models require well-defined biomimetic microenvironments. During the past decade, innovative developments in materials science, microfabrication, and polymer science have provided us with the ability to manipulate cellular microenvironments for regenerative medicine and tissue engineering applications. Solution blow spinning is a facile fiber fabricating method that requires a simple apparatus, a concentrated polymer solution within a volatile solvent, and a high-pressure gas source. Commercially available airbrushes, typically used for painting and cosmetic makeup, have successfully generated a range of nanofibers and films. Applications under investigation are similar to electrospinning and include enzyme immobilization, drug delivery, filtration, infection protection, tissue engineering, and wound healing. This review will discuss fiber fabrication methods before a more detailed discussion of the potential of blow-spinning in biomedical applications.

Automated summary

Human tissues and disease models require biomimetic microenvironments. Solution blow spinning is a facile method for fabricating nanofibers and films, with various applications in areas such as tissue engineering and wound healing. This review discusses fiber fabrication methods and explores the potential of blow-spinning in biomedical applications.