期刊
MARINE DRUGS
卷 14, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/md14010023
关键词
oxylipins; macroalgae; phytoprostanes; biosynthesis; bioactivity
资金
- European Union
- National Funds (FCT, Fundacao para a Ciencia e Tecnologia) [UID/QUI/50006/2013]
- FCT [SFRH/BD/95861/2013]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/95861/2013] Funding Source: FCT
Marine algae are rich and heterogeneous sources of great chemical diversity, among which oxylipins are a well-recognized class of natural products. Algal oxylipins comprise an assortment of oxygenated, halogenated, and unsaturated functional groups and also several carbocycles, varying in ring size and position in lipid chain. Besides the discovery of structurally diverse oxylipins in macroalgae, research has recently deciphered the role of some of these metabolites in the defense and innate immunity of photosynthetic marine organisms. This review is an attempt to comprehensively cover the available literature on the chemistry, biosynthesis, ecology, and potential bioactivity of oxylipins from marine macroalgae. For a better understanding, enzymatic and nonenzymatic routes were separated; however, both processes often occur concomitantly and may influence each other, even producing structurally related molecules.
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