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Layered double hydroxides: a gleam on their synthetic routes with biomedical applications

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SPRINGER HEIDELBERG
DOI: 10.1007/s12008-023-01333-5

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Anionic clays; Layered double hydroxides; Biocompatible; Environment sustainability

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Layered double hydroxides (LDHs) are being extensively studied in recent years due to their composition, reusability, cost effectiveness, and ease of synthesis. These materials are considered as green materials because they are non-toxic, easily obtained, and can be produced at low cost using aqueous medium conditions with less hazardous effluents. The simplified method involves one-pot route synthesis using low cost and abundant chemical precursors under mild reaction conditions. LDHs have attracted attention for their various characteristics such as acidic and basic properties, unique diffusion properties, ion-exchangeability, self-healing, and surface modification, making them applicable in energy, environment, catalysis, and biomedical fields. This study focuses on various production methods and their applicability in the biomedical field as delivery agents of bioactive molecules.
Layered double hydroxides (LDHs) are prominent class of anionic clays which have been recently investigated to be involved in various applications due to composition, reusability, cost effectiveness and facile synthesis. Altogether, these materials can be termed as green materials on the basis of their non-toxic nature, availability of their precursors, facile and low cost of production using aqueous medium conditions with less hazardous effluents. The simplified method of these lamellar materials involves facile one-pot route synthesis from low cost, abundant and commonly available chemical precursors through the aqueous synthetic pathways under mild reaction conditions. Various convincing characteristics namely acidic and basic properties, unique diffusion properties, ion-exchangeability, self-healing (memory effect) and surface modification etc. have attracted considerable attention for their applicability in various fields related to energy, environment, catalysis and biomedical sector. This study enlightens about a variety of production methods with applicability in the biomedical field as delivery agent of bioactive molecules such as drugs, cosmeceuticals etc.

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