期刊
MAGNETIC RESONANCE IN MEDICINE
卷 78, 期 4, 页码 1599-1606出版社
WILEY
DOI: 10.1002/mrm.26517
关键词
safety; specific absorption rate; thermoacoustics
资金
- NIH [P41 EB015891]
- NSERC
- GE Healthcare
PurposeTo develop a new method capable of directly measuring specific absorption rate (SAR) deposited in tissue using the thermoacoustic signal induced by short radiofrequency (RF) pulse excitation. TheoryA detailed model based on the thermoacoustic wave generation and propagation is presented. MethodsWe propose a new concept for direct measurement of SAR, to be used as a safety assessment/monitoring tool for MRI. The concept involves the use of short bursts of RF energy and the measurement of the resulting thermoacoustic excitation pattern by an array of ultrasound transducers, followed by image reconstruction to yield the 3D SAR distribution. We developed a simulation framework to model this thermoacoustic SAR mapping concept and verified the concept in vitro. ResultsSimulations show good agreement between reconstructed and original SAR distributions with an error of 4.2, 7.2, and 8.4% of the mean SAR values in axial, sagittal, and coronal planes and support the feasibility of direct experimental mapping of SAR distributions in vivo. The in vitro experiments show good agreement with theory (r(2)=0.52). ConclusionsA novel thermoacoustic method for in vivo mapping of local SAR patterns in MRI has been proposed and verified in simulation and in a phantom experiment. Magn Reson Med 78:1599-1606, 2017. (c) 2016 International Society for Magnetic Resonance in Medicine
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