4.5 Article

Asiaticoside ameliorates renal ischemia/reperfusion injury by promoting CD4+CD25+FOXP3+treg cell differentiation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance

Yang Zhang et al.

Summary: Research has shown that inflammation plays a critical role in renal ischemia-reperfusion injury (IRI), with T lymphocytes being key players in the resulting inflammation. Connexin 43 (Cx43) is involved in maintaining T lymphocyte homeostasis. Estrogen has been identified as a renoprotective agent due its anti-inflammatory properties. This study aimed to investigate the role of Cx43-activated T lymphocytes in the protective effects of 17 beta-estradiol against renal IRI.

DISEASE MARKERS (2022)

Article Immunology

Dioscin alleviates hashimoto's thyroiditis by regulating the SUMOylation of IRF4 to promote CD4+CD25+Foxp3+ treg cell differentiation

Cao Yongjun et al.

Summary: The study revealed that the proportions of CD4(+)CD25(+) Treg cells and the expression of Foxp3 were significantly decreased in HT patients, while the expression of SENP1 was enhanced. However, in the dioscin-treated group, the proportions of CD4(+)CD25(+)Foxp3(+) Treg cells were increased, along with increased expression of Foxp3, SUMO-1, and SUMO-2/3, and decreased expression of SENP1.

AUTOIMMUNITY (2021)

Article Medicine, General & Internal

Salidroside regulates imbalance of Th17/Treg and promotes ischemic tolerance by targeting STAT-3 in cerebral ischemia-reperfusion injury

Lele Yin et al.

Summary: The study showed that salidroside can significantly alleviate neurological deficits and infarct size in rats with cerebral ischemia-reperfusion injury by targeting STAT-3 to reverse the imbalance of Th17 and Treg cells. Sal also inhibits the expression of inflammatory factors in rat brain tissue, reversing apoptotic brain cell death. The results suggest that Sal has a significant protective effect on rats with middle cerebral artery occlusion.

ARCHIVES OF MEDICAL SCIENCE (2021)

Article Medicine, Research & Experimental

Theaflavin ameliorates renal ischemia/reperfusion injury by activating the Nrf2 signalling pathway in vivo and in vitro

Zhongyuan Li et al.

Summary: Theaflavin has been shown to protect against renal ischemia/reperfusion injury by inhibiting oxidative stress and apoptosis, promoting mitochondrial function and activating the Nrf2-NQO1/HO-1 pathway. These findings suggest the potential of theaflavin as a clinical therapeutic for acute kidney injury.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Biochemistry & Molecular Biology

Asiaticoside attenuates bleomycin-induced pulmonary fibrosis in A2aR-/- mice by promoting the BMP7/Smad1/5 signaling pathway

Ting Zhang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Article Physiology

METTL3 contributes to renal ischemia-reperfusion injury by regulating Foxd1 methylation

Fanhang Meng et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2020)

Article Biochemistry & Molecular Biology

Cordycepin protects renal ischemia/reperfusion injury through regulating inflammation, apoptosis, and oxidative stress

Feng Han et al.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2020)

Review Immunology

The pathogenicity of Th17 cells in autoimmune diseases

Keiko Yasuda et al.

SEMINARS IN IMMUNOPATHOLOGY (2019)

Review Medicine, General & Internal

Acute kidney injury

Claudio Ronco et al.

LANCET (2019)

Review Pediatrics

The role of CD47 in pathogenesis and treatment of renal ischemia reperfusion injury

Jeffrey S. Isenberg et al.

PEDIATRIC NEPHROLOGY (2019)

Article Dentistry, Oral Surgery & Medicine

Asiaticoside induces osteogenic differentiation of human periodontal ligament cells through the Wnt pathway

Atika Resti Fitri et al.

JOURNAL OF PERIODONTOLOGY (2018)

Article Biochemistry & Molecular Biology

Zhenbao Pill reduces Treg cell proportion in acute spinal cord injury rats by regulating TUG1/miR-214/HSP27 axis

Yongxiong He et al.

BIOSCIENCE REPORTS (2018)

Article Cell Biology

Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets

Vasumathi Kameswaran et al.

CELL METABOLISM (2014)