期刊
MACROMOLECULAR CHEMISTRY AND PHYSICS
卷 218, 期 2, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/macp.201600422
关键词
aqueous two-phase system; bioactivity preservation; droplet microfluidics; phase separation
资金
- Early Career Scheme [HKU 707712P]
- General Research Fund [HKU 719813E, 17304514, 17306315]
- Collaborative Research Fund from Research Grants Council of Hong Kong [C6004-14G]
- Major Research Plan from National Natural Science Foundation of China [91434202]
- Seed Funding Program for Basic Research from University of Hong Kong [201511159280, 201411159038]
- [21476189/B060201]
In this study, Janus droplets are fabricated by inducing phase separation of single-phase droplets made up of an aqueous two-phase system (ATPS). The resultant Janus droplets are highly monodisperse in structures and internal morphologies. Due to the affinity partitioning properties of ATPS, encapsulated ingredients can automatically partition into different compartments of the resultant Janus droplets. The use of biocompatible and cytocompatible ATPS also enables the encapsulation of enzymes and cells in the resultant droplets with their activity preserved at a relatively high level.
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