期刊
ANNALS OF GASTROENTEROLOGICAL SURGERY
卷 -, 期 -, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ags3.12704
关键词
administrative claims; gastrointestinal neoplasms; patient outcome assessment; postoperative complications; validation study
This study aims to evaluate the accuracy of extracting patients who underwent GI cancer surgery and postoperative complications from Japanese administrative claims data. The method was validated using data from Kyoto University Hospital and two other hospitals, and the results showed that it accurately identified postoperative complications requiring interventions. This study is of great importance for hospital quality improvement or large-scale comparison studies among nationwide hospitals.
Background Recently, real-world data have been recognized to have a significant role for research and quality improvement worldwide. The decision on the existence or nonexistence of postoperative complications is complex in clinical practice. This multicenter validation study aimed to evaluate the accuracy of identification of patients who underwent gastrointestinal (GI) cancer surgery and extraction of postoperative complications from Japanese administrative claims data.Methods We compared data extracted from both the Diagnosis Procedure Combination (DPC) and chart review of patients who underwent GI cancer surgery from April 2016 to March 2019. Using data of 658 patients at Kyoto University Hospital, we developed algorithms for the extraction of patients and postoperative complications requiring interventions, which included an invasive procedure, reoperation, mechanical ventilation, hemodialysis, intensive care unit management, and in-hospital mortality. The accuracy of the algorithms was externally validated using the data of 1708 patients at two other hospitals.Results In the overall validation set, 1694 of 1708 eligible patients were correctly extracted by DPC (sensitivity 0.992 and positive predictive value 0.992). All postoperative complications requiring interventions had a sensitivity of >0.798 and a specificity of almost 1.000. The overall sensitivity and specificity of Clavien-Dindo = grade IIIb complications was 1.000 and 0.995, respectively.Conclusion Patients undergoing GI cancer surgery and postoperative complications requiring interventions can be accurately identified using the real-world data. This multicenter external validation study may contribute to future research on hospital quality improvement or to a large-scale comparison study among nationwide hospitals using real-world data.
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