☆ 4.7 Review

Polysaccharide-Based Multifunctional Hydrogel Bio-Adhesives for Wound Healing: A Review

GELS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Multifunctional hydrogels based on chitosan, hyaluronic acid and other biological macromolecules for the treatment of inflammatory bowel disease: A review

Yongliang Ouyang et al.

Summary: Hydrogel, as a water-rich polymer material, is widely used in the biomedical field due to its unique physical and chemical properties and good biocompatibility. With the increasing incidence of inflammatory bowel disease (IBD) in recent years, traditional drug treatments have shown limitations, resulting in an urgent need for new therapies. Hydrogel has emerged as a potential therapeutic platform for IBD, but there is a lack of comprehensive review on functional hydrogels for IBD treatment.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Biochemistry & Molecular Biology

Injectable wound dressing based on carboxymethyl chitosan triple-network hydrogel for effective wound antibacterial and hemostasis

Zheng Chen et al.

Summary: In this study, a multifunctional COP hydrogel composed of CMCS, OD, and γ-PGA was prepared for antimicrobial and hemostasis of diffuse wounds. The COP hydrogel exhibited significant antibacterial effects, inhibited bacterial growth, and promoted wound healing. It also showed superior hemostasis ability in a rat tail diffuse hemorrhage wound model. Therefore, the multifunctional COP hydrogel is expected to have important applications in wound hemostasis and healing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Materials Science, Multidisciplinary

An oxidative polymerized carboxymethyl cellulose hydrogel for the combined anti-tumor recurrence

Yangbei Zhu et al.

Summary: We developed a hydrogel-based drug-carrying system to prevent postoperative tumor recurrence. The hydrogel was prepared by modifying sodium carboxymethyl cellulose with dopamine and incorporating KMnO4 as an oxidizing agent. The hydrogel exhibited T-2-weighted MRI capability and could be used for tumor photodynamic therapy (PDT) and photothermal therapy (PTT) with the introduction of a photosensitizer.

JOURNAL OF MATERIALS SCIENCE (2023)

添加到收藏夹
Review Biochemistry & Molecular Biology

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

Jinjin Pei et al.

Summary: Poor wound healing affects millions of people worldwide, leading to increased mortality rates and healthcare costs. Bio-based materials have shown great potential in enhancing wound healing by stimulating cellular and molecular processes, inhibiting pathogens, preventing inflammation, and promoting angiogenesis.

MOLECULES (2023)

添加到收藏夹
Article Biochemistry & Molecular Biology

Wound Healing Properties of Natural Products: Mechanisms of Action

Marilyn S. Criollo-Mendoza et al.

MOLECULES (2023)

添加到收藏夹
Review Biochemistry & Molecular Biology

Chitosan-Based Hemostatic Hydrogels: The Concept, Mechanism, Application, and Prospects

Peng Fan et al.

Summary: This paper reviews the recent research progress of chitosan-based hemostatic hydrogels and their advantageous characteristics compared to traditional hemostatic materials. The effects of the hemostatic mechanism, effects of deacetylation degree, relative molecular mass, and chemical modification on the hemostatic performance of chitosan hydrogels are summarized. Meanwhile, some typical applications of chitosan hydrogels are introduced to provide references for the preparation of efficient hemostatic hydrogels. Finally, the future perspectives of chitosan-based hemostatic hydrogels are presented.

MOLECULES (2023)

添加到收藏夹
Article Chemistry, Inorganic & Nuclear

A molybdenum-based nanoplatform with multienzyme mimicking capacities for oxidative stress-induced acute liver injury treatment

Zhirui Zhang et al.

Summary: In this study, a simple and economical method was reported to synthesize MoS2-PEG@BSA (MPB) nanosheets, which possess the ability to scavenge different types of reactive oxygen species and mimic the activities of catalase, superoxide dismutase, and glutathione peroxidase. The biocompatibility of the MPB platform was greatly improved by modification with bovine serum albumin, and it effectively relieved acute liver injury caused by oxidative stress. Both in vitro and in vivo experiments confirmed the biocompatibility and efficiency of MPB nanosheets in cell protection.

INORGANIC CHEMISTRY FRONTIERS (2023)

添加到收藏夹
Review Pharmacology & Pharmacy

Natural Compounds and Biopolymers-Based Hydrogels Join Forces to Promote Wound Healing

Federica Falbo et al.

Summary: Rapid and complete wound healing is important in pathological conditions such as Type 2 Diabetes mellitus. Wound dressings, particularly biocompatible hydrogels, play a crucial role in diabetic wound healing by retaining moisture and preventing bacterial infection. In recent years, functionalized hydrogels with natural bioactive compounds and biomacromolecules have shown promising outcomes in promoting healing and exhibiting antibacterial activity. This review discusses the discoveries and advancements in using naturally occurring compounds and biopolymers for wound healing, as well as emerging approaches and devices for effective wound care in diabetic patients.

PHARMACEUTICS (2023)

添加到收藏夹
Review Pharmacology & Pharmacy

Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology

Yi Lu et al.

Summary: In 2022, icaritin soft capsules were approved by the NMPA of China for the treatment of HCC. However, the low content, poor bioavailability, and unfavorable delivery efficiency of epimedium flavonoids have hampered their production efficiency and clinical applications. Various strategies, including enzyme engineering and nanotechnology, have recently been developed to increase productivity, improve delivery efficiency, and enhance therapeutic effects. This review discusses the structure-activity relationship of epimedium flavonoids, enzymatic engineering strategies, and nanomedicines for overcoming delivery barriers and improving therapeutic effects.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2023)

添加到收藏夹
Review Food Science & Technology

Recent Advances in Cellulose-Based Hydrogels: Food Applications

Pinku Chandra Nath et al.

Summary: In recent years, cellulose has attracted significant attention as a abundant and renewable source of hydrogels. Researchers are focusing on naturally produced hydrogels due to their biocompatibility, biodegradability, and abundance to address environmental issues and emerging demand. Cellulose-based hydrogels have functional characteristics that make them important in different aspects of the food industry, including food packaging, functional food, food safety, and drug delivery. This article discusses the sources, types, and preparation methods of cellulose-based hydrogels, as well as their recent developments and uses in the food processing sector.

FOODS (2023)

添加到收藏夹
Article Chemistry, Applied

A Schiff base hydrogel dressing loading extracts from Periplaneta Americana for diabetic wound healing

Fengbiao Guo et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Biochemistry & Molecular Biology

Injectable carboxymethyl chitosan-based hydrogel for simultaneous anti-tumor recurrence and anti-bacterial applications

Yang Yu et al.

Summary: An injectable PCP hydrogel was developed to reduce post-operative infection and prevent tumor recurrence. The hydrogel effectively killed tumor cells and bacteria, and exhibited anti-bacterial and anti-tumor properties.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Biochemistry & Molecular Biology

Bioactive bacterial cellulose wound dressings for burns with collagen in-situ and chitosan ex-situ impregnation

Khatarina Meldawati Pasaribu et al.

Summary: Bacterial cellulose (BC) is a biopolymer commonly used as wound dressing due to its high biocompatibility. Chitosan and collagen can be impregnated into BC fibers to optimize its properties. The BC-based wound dressing showed good intermolecular interactions and penetration of chitosan and collagen, as confirmed by FTIR and SEM. Other tests demonstrated the non-hemolytic nature and effectiveness of the wound dressing. In-vivo test showed that BC/collagen/chitosan wound dressing supported wound healing in second degree burns.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Biochemistry & Molecular Biology

Electroactive injectable hydrogel based on oxidized sodium alginate and carboxymethyl chitosan for wound healing

Lin Zhao et al.

Summary: An electroactive hydrogel was constructed by rapidly forming dynamic imine bonds between oxidized sodium alginate (OSA) and carboxymethyl chitosan (CMCS), and in situ forming silver nanoparticles (AgNPs) by UV irradiation. The hydrogel exhibited injectability, self-healing ability, biocompatibility, and antibacterial activities. It promoted cell proliferation and accelerated wound healing in a skin defect model.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Biochemistry & Molecular Biology

Chitosan/glycyrrhizic acid hydrogel: Preparation, characterization, and its potential for controlled release of gallic acid

Mostafa Saeedi et al.

Summary: In this study, chitosan was crosslinked using glycyrrhizic acid as a new crosslinking agent, and the obtained hydrogels showed biocompatibility for controlled release of gallic acid in transdermal therapy. The crosslinking of chitosan with glycyrrhizic acid formed a covalent amide linkage, resulting in the formation of a crosslinked hydrogel network structure.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

添加到收藏夹
Article Biophysics

Sodium alginate hydrogel containing platelet-rich plasma for wound healing

Ting Wang et al.

Summary: In recent years, the healing of chronic wounds has become a challenging problem in clinical practice. This study aimed to address the challenges in wound care by designing a dual-network hydrogel composed of sodium alginate and platelet-rich plasma. The hydrogel showed a three-dimensional network structure and exhibited the potential for cell proliferation and vascular regeneration. When applied to wound skin in rats, the hydrogel effectively promoted wound closure. Overall, this strategy offers a simple and feasible approach for overcoming the shortcomings of conventional wound dressings.

COLLOIDS AND SURFACES B-BIOINTERFACES (2023)

添加到收藏夹
Review Polymer Science

Application of Polymer Hydrogels in the Prevention of Postoperative Adhesion: A Review

Jie Cai et al.

Summary: Postoperative adhesion is a common complication after surgery, involving the formation of fibrous bridges between different layers of tissues. Despite progress in understanding the mechanism, effective prevention of adhesion is still challenging. Hydrogels, as water-expanding polymers with drug-loading capability, have shown promising antifouling abilities for preventing postoperative adhesion. This review summarizes the current research status of hydrogels as anti-adhesion barriers, highlights their characteristics in preventing adhesion, and discusses future research directions.

GELS (2023)

添加到收藏夹
Review Polymer Science

Advances in Hemostatic Hydrogels That Can Adhere to Wet Surfaces

Wenli Han et al.

Summary: Currently, uncontrolled bleeding remains a serious problem in emergency, surgical and battlefield environments. In recent years, polymeric hydrogels with excellent hemostatic properties have received much attention because of their adjustable mechanical properties, high porosity, and biocompatibility. This review aims to investigate the role of hydrogels in hemostasis, by elucidating the mechanisms of hydrogel hemostasis and adhesion, introducing the adhesion design strategies of hemostatic hydrogels in wet environments, summarizing the studies and in vivo applications of wet-adhesive hemostatic hydrogels in different environments, and proposing the improvement directions of such hydrogels in future studies.

GELS (2023)

添加到收藏夹
Article Chemistry, Multidisciplinary

pH/Glucose Dual Responsive Metformin Release Hydrogel Dressings with Adhesion and Self-Healing via Dual-Dynamic Bonding for Athletic Diabetic Foot Wound Healing

Yongping Liang et al.

Summary: A dual-responsive hydrogel dressing was constructed for the treatment of type II diabetic foot ulcers and shown to promote wound healing in a rat model. The addition of metformin and graphene oxide further enhanced wound repair.

ACS NANO (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Adhesive Hemostatic Hydrogel with Ultrafast Gelation Arrests Acute Upper Gastrointestinal Hemorrhage in Pigs

Xianfeng Xia et al.

Summary: A novel hemostatic hybrid hydrogel comprised of hyaluronic acid and polyethylene glycol stabilized by thiourea-catechol coupling and disulfide bonds is reported for endoscopic hemostasis in upper GI hemorrhage. The hybrid hydrogels exhibit enhanced mechanical properties and good blood clotting ability, showing promising results in both rat and pig models. The sustained hemostatic function of the hybrid hydrogels make them a potential candidate for clinical applications in endoscopic hemostasis.

ADVANCED FUNCTIONAL MATERIALS (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Anti-Swelling, Robust, and Adhesive Extracellular Matrix-Mimicking Hydrogel Used as Intraoral Dressing

Jing Wu et al.

Summary: This study developed a family of bioinspired hydrogels for intraoral wound repair, which can control swelling and provide durable protection, leading to accelerated wound healing.

ADVANCED MATERIALS (2022)

添加到收藏夹
Article Chemistry, Applied

Dextran and peptide-based pH-sensitive hydrogel boosts healing process in multidrug-resistant bacteria-infected wounds

Siwen Wu et al.

Summary: We have developed a dual functional hydrogel that can kill multidrug-resistant bacteria and promote scarless wound healing.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹
Article Engineering, Environmental

Mimicking skin cellulose hydrogels for sensor applications

Daihui Zhang et al.

Summary: The study successfully fabricated a biocompatible cellulose biomimetic hydrogel with skin-like properties, showing excellent performance in toughness, stretchability, elasticity, and self-stiffness. By utilizing the crystallization behavior of cellulose, the design mimics the skin's structures, limiting water swelling and enabling the preparation of high-performance strain sensors.

CHEMICAL ENGINEERING JOURNAL (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Antibacterial Copolypeptoids with Potent Activity against Drug Resistant Bacteria and Biofilms, Excellent Stability, and Recycling Property

Bo Zhang et al.

Summary: This study reports the development of an innovative cationic copolypeptoid antimicrobial that exhibits a wide spectrum of antibacterial activity and low hemolytic properties. It effectively inhibits biofilm formation and eradicates bacteria embedded in mature biofilms. The antimicrobial also shows potent activity against drug-resistant bacteria without developing visible resistance after repeated usage.

SMALL (2022)

添加到收藏夹
Article Nanoscience & Nanotechnology

Gallium(III)-Mediated Dual-Cross-Linked Alginate Hydrogels with Antibacterial Properties for Promoting Infected Wound Healing

Jiajun Qin et al.

Summary: Gallium metal has great potential in fighting infections by disrupting bacterial iron metabolism. This study explores the use of gallium-mediated hydrogel for treating infected wounds. The innovative design of a dual-cross-linked alginate hydrogel, with gallium as a crosslinking and therapeutic agent, showed broad-spectrum antimicrobial activity and improved mechanical performance. In vitro and in vivo results demonstrated the biocompatibility, reduced bacterial growth, and accelerated healing of infected wounds, making the gallium-incorporated hydrogel an ideal antimicrobial dressing.

ACS APPLIED MATERIALS & INTERFACES (2022)

添加到收藏夹
Article Engineering, Biomedical

Hyaluronic acid-based glucose-responsive antioxidant hydrogel platform for enhanced diabetic wound repair

Zejun Xu et al.

Summary: In this study, a glucose-responsive HA-based hydrogel platform was developed for rapid repair of diabetic wounds. The HMPC hydrogel effectively promoted angiogenesis and reduced inflammatory response, leading to the rapid recovery of diabetic wounds.

ACTA BIOMATERIALIA (2022)

添加到收藏夹
Review Chemistry, Applied

Chondroitin Sulfate: Emerging biomaterial for biopharmaceutical purpose and tissue engineering

Reena Sharma et al.

Summary: Chondroitin Sulfate (CS) is a versatile polysaccharide with various activities such as anti-inflammatory, antioxidant, antitumor, and anticoagulant. It is biodegradable, biocompatible, and capable of targeted drug delivery and site-specific drug release. CS-based nanocarriers and stimuli-sensitive delivery systems have promising applications in drug delivery, tissue engineering, wound healing, and tumor targeting.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹
Article Engineering, Environmental

Multifunctional hydrogel as wound dressing for intelligent wound monitoring

Lirong Wang et al.

Summary: The multifunctional hydrogel wound dressing promotes wound healing by providing antibacterial, hemostatic, and adhesive properties, while also enabling real-time monitoring of wound status. The personalized wound management model accurately analyzes and evaluates wound healing and infection status using the colorimetric signal of the hydrogel dressing, achieving high accuracy.

CHEMICAL ENGINEERING JOURNAL (2022)

添加到收藏夹
Article Biochemistry & Molecular Biology

Novel dopamine-modified oxidized sodium alginate hydrogels promote angiogenesis and accelerate healing of chronic diabetic wounds

Jinhua Chi et al.

Summary: In this study, dopamine was successfully grafted with oxidized sodium alginate to fabricate OSA-DA hydrogels with enhanced biocompatibility and suitable adhesion. The hydrogels exhibited appropriate swelling ratio and adhesion characteristics, and demonstrated satisfactory cytocompatibility in cells and biocompatibility in animals. Moreover, OSA-DA hydrogels showed remarkable promoting effects on angiogenesis and wound healing, making them a potential clinical wound dressing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

A Dual-Cross-Linked Hydrogel Patch for Promoting Diabetic Wound Healing

Jing Liu et al.

Summary: This study designed a hemostatic and anti-inflammatory hydrogel patch for promoting diabetic wound healing. The hydrogel was able to regulate macrophage phenotype, promote fibroblast proliferation and migration, and accelerate angiogenesis. The hydrogel can effectively promote wound closure and tissue regeneration, making it a simple, economical, effective, and safe treatment for diabetic wounds.

SMALL (2022)

添加到收藏夹
Article Multidisciplinary Sciences

Superstrong, superstiff, and conductive alginate hydrogels

Donghwan Ji et al.

Summary: In this study, the authors demonstrate the synthesis of superstrong, superstiff, and conductive alginate hydrogels with densely interconnecting networks. By using a simple reconstructing process, they achieve specific mechanical properties required for applications in artificial biological tissues, flexible electronics, and conductive membranes. The hydrogels show exceptional tensile strengths and elastic moduli, and they can also hold cations and exhibit high ionic conductivity.

NATURE COMMUNICATIONS (2022)

添加到收藏夹
Article Engineering, Biomedical

Supramolecular Thermo-Contracting Adhesive Hydrogel with Self-Removability Simultaneously Enhancing Noninvasive Wound Closure and MRSA-Infected Wound Healing

Rui Yu et al.

Summary: A novel supramolecular poly(N-isopropylacrylamide) hybrid hydrogel dressing with thermal contraction and tissue adhesion properties, as well as multiple mechanical and biological properties, is developed to achieve noninvasive wound closure and enhance wound healing simultaneously.

ADVANCED HEALTHCARE MATERIALS (2022)

添加到收藏夹
Article Engineering, Biomedical

Construction of multifunctional hydrogel based on the tannic acid-metal coating decorated MoS2 dual nanozyme for bacteria-infected wound healing

Yang Li et al.

Summary: A hydrogel with antibacterial and antioxidant properties is developed to treat bacterial-infected wounds. The hydrogel can alleviate the inflammatory response and tissue hypoxia of infected wounds. Additionally, the hydrogel exhibits fast self-healing and shape adaptability.

BIOACTIVE MATERIALS (2022)

添加到收藏夹
Article Biochemistry & Molecular Biology

Bacterial and Viral Infection and Sepsis in Kidney Transplanted Patients

Alberto Mella et al.

Summary: Kidney transplanted patients have a higher vulnerability to viral and bacterial infections due to continuous immunosuppression, making infectious episodes a major cause of death. Prevention, early diagnosis, and appropriate therapy are crucial in managing these infections.

BIOMEDICINES (2022)

添加到收藏夹
Article Engineering, Biomedical

Architecting polyelectrolyte hydrogels with Cu-assisted polydopamine nanoparticles for photothermal antibacterial therapy

ZhangPing Li et al.

Summary: This study presents a promising strategy for constructing a facile and safe photothermal agent for photothermal antibacterial therapy. The developed PDA@Cu nanoparticles exhibit high photothermal conversion efficiency and enhanced antibacterial performance, making it an appealing biomimetic agent for antibacterial treatment.

MATERIALS TODAY BIO (2022)

添加到收藏夹
Article Chemistry, Applied

Polyphenol-driving assembly for constructing chitin-polyphenol-metal hydrogel as wound dressing

Xinghuan Lin et al.

Summary: Metal-polyphenol networks have attracted attention for biomedical applications. A new non-covalent driven assembly strategy was developed to fabricate chitin-polyphenol-metal hydrogels. The hydrogel showed antibacterial properties and promoted wound healing.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹
Article Medicine, Research & Experimental

Recent advances in the medical applications of hemostatic materials

Yu Guo et al.

Theranostics (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Sustainable Mitigation of Paracetamol with a Novel Dual-Functionalized Pullulan/Kaolin Hydrogel Nanocomposite from Simulated Wastewater

Suhail Ayoub Khan et al.

Summary: A novel dual-functionalized pullulan/kaolin hydrogel nanocomposite (f-PKHN) was fabricated and demonstrated significant adsorption capacity, green characteristics, and excellent reusability for the removal of PCT from aquatic sources and industrial effluents.

LANGMUIR (2022)

添加到收藏夹
Article Chemistry, Applied

A bioactive dextran-based hydrogel promote the healing of infected wounds via antibacterial and immunomodulatory

Lisheng Zhou et al.

Summary: A dextran-based hydrogel loaded with black phosphorus nanosheets and zinc oxide nanoparticles exhibits synergistic antibacterial activity and reduces macrophage polarization, promoting the healing of infected wounds.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹
Article Chemistry, Applied

New injectable chitosan-hyaluronic acid based hydrogels for hemostasis and wound healing

Hongjuan Weng et al.

Summary: Novel NSC-OHA-based hydrogels with self-healing and injectable properties were fabricated, and the mechanical behavior and bioactivities were regulated by the addition of Ca2+ or PEG1. The hydrogels showed improved biocompatibility, hemostasis, and wound healing abilities, making them promising for medical applications.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹
Article Chemistry, Applied

Biomedical engineering of polysaccharide-based tissue adhesives: Recent advances and future direction

Hanieh Shokrani et al.

Summary: Tissue adhesives are widely used for wound treatment, prevention of wound leaks, severe bleeding, and drug delivery. Future research needs to focus on understanding biomaterials, tissue surface properties, fabrication procedures, and the development of new adhesive technologies.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹
Article Biochemistry & Molecular Biology

Multifunctional carboxymethyl chitosan/oxidized dextran/sodium alginate hydrogels as dressing for hemostasis and closure of infected wounds

Mengmeng Xie et al.

Summary: A multifunctional hydrogel has been developed that can rapidly stop bleeding and has antibacterial properties, promoting wound healing and repair. The hydrogel has good water retention capacity and mimics the three-dimensional structure of the natural extracellular matrix, making it promising for applications in hemostasis and wound healing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

添加到收藏夹
Article Engineering, Biomedical

Multi-crosslinking hydrogels with robust bio-adhesion and pro-coagulant activity for first-aid hemostasis and infected wound healing

Chen-Yu Zou et al.

Summary: Bio-adhesive polysaccharide-based hydrogels with improved mechanical properties and bio-adhesion have been developed. These hydrogels exhibit excellent biocompatibility, antibacterial property and pro-healing bioactivity. They show superior hemostatic performance and promote infected wound healing due to their enhanced adhesive properties and procoagulant activity.

BIOACTIVE MATERIALS (2022)

添加到收藏夹
Review Chemistry, Multidisciplinary

Polymers showing intrinsic antimicrobial activity

Meltem Haktaniyan et al.

Summary: Pathogenic microorganisms are a major threat to human health and the increasing levels of antimicrobial resistance require new approaches, such as antimicrobial polymers. These polymers, derived from natural sources or synthesized with enhancing elements, have shown intrinsic antimicrobial properties and can be used as surface coatings or antibacterial agents in various applications.

CHEMICAL SOCIETY REVIEWS (2022)

添加到收藏夹
Article Materials Science, Multidisciplinary

Injectable melatonin-loaded carboxymethyl chitosan (CMCS)-based hydrogel accelerates wound healing by reducing inflammation and promoting angiogenesis and collagen deposition

Kai Chen et al.

Summary: The melatonin-loaded hydrogel promotes granulation tissue formation, accelerates wound healing, and reduces inflammation levels.

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Polysaccharide-Peptide Conjugates: A Versatile Material Platform for Biomedical Applications

Hai-Qing Song et al.

Summary: This review summarizes the potential and advantages of polysaccharide-peptide conjugates in biomedical applications, as well as provides an overview of the design, conjugation chemistry, and applications. In addition, the challenges and demands of polysaccharide-peptide conjugates are also discussed for future prospects.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹
Article Materials Science, Biomaterials

Injectable, self-healing, antibacterial, and hemostatic N,O-carboxymethyl chitosan/oxidized chondroitin sulfate composite hydrogel for wound dressing

Hongbin Li et al.

Summary: This work reports the development of an injectable, self-healing, antibacterial, hemostatic, and biocompatible hydrogel derived from the hybrid of N,O-carboxymethyl chitosan and oxidized chondroitin sulfate, which does not require any chemical crosslinking. The hydrogel exhibited excellent in vivo hemostatic performance and low cell toxicity, making it a promising wound dressing material.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

Conductive, Self-Healing, Adhesive, and Antibacterial Hydrogels Based on Lignin/Cellulose for Rapid MRSA-Infected Wound Repairing

Pengpeng Deng et al.

Summary: This study developed multifunctional hydrogels based on lignin and cellulose, exhibiting excellent physical and biological properties for treating infected wounds and promoting wound healing.

ACS APPLIED MATERIALS & INTERFACES (2021)

添加到收藏夹
Article Chemistry, Applied

Nonswelling injectable chitosan hydrogel via UV crosslinking induced hydrophobic effect for minimally invasive tissue engineering

Haichang Ding et al.

Summary: A new nonswelling pentenyl chitosan hydrogel was developed via UV crosslinking, which maintains a nonswelling state at biological temperature. The hydrogel showed no cytotoxicity in vitro and demonstrated minimal adverse effects in a rat model. The injectable and UV crosslinkable chitosan hydrogel holds potential applications in smart biomaterials and minimally invasive tissue engineering.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Chemically Modified Biopolymers for the Formation of Biomedical Hydrogels

Victoria G. Muir et al.

Summary: Biopolymers are natural polymers sourced from plants and animals, with inherent biochemical and biophysical properties that make them suitable for biomedical hydrogels. Various chemical modifications and cross-linking methods are used to design and develop biopolymer hydrogels for applications such as tissue scaffolds, therapeutic delivery, and tissue adhesives. Recent advances in the field include the use of chemically modified biopolymer hydrogels and interpenetrating network biopolymer hydrogels.

CHEMICAL REVIEWS (2021)

添加到收藏夹
Review Biochemistry & Molecular Biology

Pullulan in biomedical research and development - A review

Ram Sarup Singh et al.

Summary: Pullulan is a microbial exo-polymer produced by yeast like fungus Aureobasidium pullulans, with distinctive physico-chemical properties that make it a potent candidate for biomedical applications.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹
Article Biophysics

Oxidation triggered formation of polydopamine-modified carboxymethyl cellulose hydrogel for anti-recurrence of tumor

Yu Zhang et al.

Summary: The research designed a hydrogel combining the abilities of PDT and PTT for tumor therapy, with good photothermal conversion, drug loading, and CT imaging capabilities.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

添加到收藏夹
Article Engineering, Multidisciplinary

Biomimetic nanocomposite hydrogel networks for robust wet adhesion to tissues

Yajun Chen et al.

Summary: Designing multifunctional medical adhesives with strong adhesiveness under water is challenging, but a combination of hydrogel matrix and nanocrystal fillers has shown potential. This hydrogel adhesive mechanism relies on absorption of interfacial water and hydration process of nanocrystals for strong cohesion, with further improvement through noncovalent and covalent bonds.

COMPOSITES PART B-ENGINEERING (2021)

添加到收藏夹
Review Chemistry, Inorganic & Nuclear

Antimicrobial MOFs

Claudio Pettinari et al.

Summary: This article discusses the recent advances in antimicrobial MOFs, covering various aspects of their biomedical applications. It outlines the potential offered by MOFs and composite materials containing MOFs in the field of antimicrobial materials, along with describing the key parameters in the design and production of antimicrobial MOFs.

COORDINATION CHEMISTRY REVIEWS (2021)

添加到收藏夹
Review Engineering, Biomedical

Conductive Materials for Healing Wounds: Their Incorporation in Electroactive Wound Dressings, Characterization, and Perspectives

Chiranjeevi Korupalli et al.

Summary: The use of conductive materials to promote the activity of electrically responsive cells is an effective means of accelerating wound healing. Recent advancements in conductive materials, particularly in their incorporation with non-conducting polymers to fabricate electroactive wound dressings, have been deliberated for their potential in monitoring the course of wound healing in vivo while simultaneously accelerating the healing process.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹
Review Materials Science, Multidisciplinary

Preparation of cellulose-based hydrogel: a review

Sarah Husnaini Zainal et al.

Summary: Cellulose, the most abundant natural organic polymer on earth, has low solubility in water and most organic solvents. Specific solvent systems are required for cellulose applications. Hydrogel, as a 3D network structure, can retain a tremendous amount of water and highly depends on the crosslinking property.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2021)

添加到收藏夹
Article Engineering, Environmental

Mussel-inspired blue-light-activated cellulose-based adhesive hydrogel with fast gelation, rapid haemostasis and antibacterial property for wound healing

Shengchang Lu et al.

Summary: The newly designed double-network adhesive hydrogels provide an effective solution for uncontrollable bleeding and wound infection, with rapid hemostatic ability, biocompatibility, and antibacterial properties, suitable for wound healing.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹
Article Materials Science, Biomaterials

Dexamethasone-loaded, injectable pullulan-poly(ethylene glycol) hydrogels for bone tissue regeneration in chronic inflammatory conditions

Neelam Chauhan et al.

Summary: Chronic inflammation caused by implants can disrupt bone tissue regeneration and there is a need for biomaterials with anti-inflammatory and oxidative stress properties to treat bone defects. A research team has successfully developed injectable polymeric hydrogels containing the anti-inflammatory drug dexamethasone, which promote osteogenesis and exhibit significant antioxidant and anti-inflammatory effects, making them suitable for bone repair treatment.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹
Article Materials Science, Biomaterials

A γ-PGA/KGM-based injectable hydrogel as immunoactive and antibacterial wound dressing for skin wound repair

Ling Zhu et al.

Summary: This study aimed to prepare an injectable hydrogel (P-OK) by combining konjac glucomannan and gamma-polyglutamic acid, which showed fast gelation time, good water-retention rate, low cytotoxicity, immunomodulating, and antibacterial capabilities. The P-OK hydrogel has the potential to shorten the healing period in wound repair dressing.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹
Article Multidisciplinary Sciences

Robust hemostatic bandages based on nanoclay electrospun membranes

Yan Cui et al.

Summary: This study reports a novel nanoclay electrospun membrane hemostatic material with excellent hemostatic effects and biocompatibility, which is a potential effective hemostat. This material can achieve rapid and effective hemostasis, suitable for prevention and emergency treatment in situations of dangerous bleeding.

NATURE COMMUNICATIONS (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Sequential Release of Small Extracellular Vesicles from Bilayered Thiolated Alginate/Polyethylene Glycol Diacrylate Hydrogels for Scarless Wound Healing

Yifan Shen et al.

Summary: The study developed bilayered thiolated alginate/PEG diacrylate (BSSPD) hydrogels for sequential release of different types of sEVs to promote wound healing. The results showed that phased release of sEVs can achieve scarless wound healing more quickly and effectively.

ACS NANO (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Dual-Dynamic-Bond Cross-Linked Antibacterial Adhesive Hydrogel Sealants with On-Demand Removability for Post-Wound-Closure and Infected Wound Healing

Yuqing Liang et al.

Summary: The research developed a smart bioadhesive hydrogel sealant with self-healing and excellent antibacterial activity, showing high effectiveness in wound closure and post-wound-closure care. The hydrogel features autonomous healing, on-demand dissolution, injectability, good biocompatibility, antibacterial properties, multifunctional adhesiveness, and NIR responsiveness. In vivo evaluation demonstrated the great potential of the smart hydrogel in dealing with skin incisions and infected full-thickness skin wounds.

ACS NANO (2021)

添加到收藏夹
Review Pharmacology & Pharmacy

Peptide-based supramolecular hydrogels for local drug delivery

Zhenghao Zhang et al.

Summary: Peptide-based supramolecular hydrogels have shown great promise as drug delivery systems due to their excellent biocompatibility, response to external stimuli, and ability to self-assemble into specific nanostructures in different environments. Utilizing inherent biological microenvironment as stimuli can provide spatiotemporal controllability for transporting therapeutics more accurately. These materials formed by weak non-covalent interactions exhibit shear-thinning and immediate recovery behavior, making them injectable and ideal for drug delivery.

ADVANCED DRUG DELIVERY REVIEWS (2021)

添加到收藏夹
Article Engineering, Biomedical

Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity

Sophia Hauck et al.

Summary: This study successfully modulated the inflammatory macrophage activities in disturbed wound healing process through the use of hydrogels containing high-sulfated hyaluronan (sHA), leading to significant effects in a mouse model.

BIOACTIVE MATERIALS (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Hydrogels as Emerging Materials for Cornea Wound Healing

Sadjad Khosravimelal et al.

Summary: Hydrogel biomaterials possess favorable characteristics for corneal tissue engineering, with the potential to repair and replace damaged tissue. Research focusing on novel hydrogels for corneal injuries has shown promising outcomes in early phase clinical trials. This emerging technology is attracting significant interest from medical devices and pharmaceutical industries, indicating a potential for new products within the next five years.

SMALL (2021)

添加到收藏夹
Article Food Science & Technology

Advanced applications of chitosan-based hydrogels: From biosensors to intelligent food packaging system

Jun Yang et al.

Summary: Chitosan-based hydrogels have excellent bioactivities and application prospects in fields such as biosensors and intelligent food packaging systems. Different types of CH-based hydrogels have different working mechanisms and extensive application prospects in delivery systems and tissue engineering.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

添加到收藏夹
Article Chemistry, Physical

Curdlan-Based Hydrogels for Potential Application as Dressings for Promotion of Skin Wound Healing-Preliminary In Vitro Studies

Aleksandra Nurzynska et al.

Summary: The study found that novel curdlan-based hydrogels enriched with Ca2+ ions showed potential as candidates for dressings to accelerate skin wound healing. They demonstrated good structural properties, water absorption capacity, and calcium ion release ability. The Cur_11% biomaterial exhibited the most desirable biological properties in vitro, releasing beneficial calcium ions that enhanced fibroblast viability and proliferation. Further studies in cell culture and in vivo are warranted to determine the precise impact of Cur_11% on skin wound healing.

MATERIALS (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Functional Hydrogels as Wound Dressing to Enhance Wound Healing

Yongping Liang et al.

Summary: Hydrogels have shown promising advantages as wound dressings due to their excellent biochemical and mechanical properties. This review summarizes the advanced functions of hydrogel dressings, such as antimicrobial, adhesion, hemostasis, anti-inflammatory, substance delivery, self-healing, stimulus response, and conductivity, as well as the emerging wound monitoring feature. The potential applications for different types of wounds, including chronic wounds and focus on infected, burn, and diabetic wounds, are discussed, along with proposed future directions for hydrogel wound dressings in wound healing.

ACS NANO (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Flexible Bicolorimetric Polyacrylamide/Chitosan Hydrogels for Smart Real-Time Monitoring and Promotion of Wound Healing

Kaikai Zheng et al.

Summary: The study presents multifunctional hydrogels for real-time monitoring of wound healing, which can detect pH level, reduce bacterial infection, and promote wound healing simultaneously. The hybridization of CQDs and pH indicator with the hydrogels allows for high responsiveness and accurate indication of pH variability, enabling real-time evaluation of wound conditions. These hydrogels have potential as a smart and flexible wound dressing platform for theranostic skin regeneration.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹
Article Chemistry, Applied

Hemostatic performance of chitosan-based hydrogel and its study on biodistribution and biodegradability in rats

Lixin Xia et al.

Summary: In this study, a degradable chitosan-based hydrogel cross-linked by oxidized hyaluronic acid was developed, showing excellent biodegradability and biocompatibility. The hydrogel exhibited good hemostatic performance in rat liver resection injury and was rapidly absorbed by the body without significant accumulation, indicating its potential as a promising hemostatic hydrogel for controlling bleeding.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹
Article Chemistry, Applied

Ultrafast in-situ forming halloysite nanotube-doped chitosan/oxidized dextran hydrogels for hemostasis and wound repair

Zhan Li et al.

Summary: Hydrogels containing halloysite nanotube-doped chitosan/oxidized dextran were developed through a Schiff base reaction, demonstrating rapid hemostasis and antibacterial effects, particularly effective for arterial and deep noncompressible bleeding wounds.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹
Article Biochemistry & Molecular Biology

Curcumin-laden hyaluronic acid-co-Pullulan-based biomaterials as a potential platform to synergistically enhance the diabetic wound repair

Syed Ahmed Shah et al.

Summary: The injectable hydrogel loaded with curcumin demonstrated a significant wound healing potential in a streptozotocin-induced diabetic rat model, showing a faster healing rate compared to other treatment groups. The hydrogel exhibited strong biocompatibility and enhanced cell proliferation, serving as a promising platform for sustained and targeted delivery of hydrophobic moieties.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹
Article Engineering, Biomedical

A mussel-inspired supramolecular hydrogel with robust tissue anchor for rapid hemostasis of arterial and visceral bleedings

Ziwen Qiao et al.

Summary: This study developed a mussel-inspired hydrogel with robust mechanical properties and excellent hemostatic efficiency by combining chitosan, silk fibroin, and tannic acid. The hydrogel showed superior performance in various arterial and visceral bleeding models, with lower blood loss and shorter time to hemostasis. The unique hydrogel could offer significant advantages in acute wounds and massive hemorrhage with restrictive access to therapeutic options.

BIOACTIVE MATERIALS (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Polydopamine antibacterial materials

Yu Fu et al.

Summary: This review provides an overview of PDA antibacterial materials, including free-standing PDA materials and PDA-based composite materials, discussing the fabrication strategies and antibacterial mechanisms, as well as presenting the future development and challenges of PDA in this field. It aims to offer insights into the future development of antibacterial functional materials based on PDA.

MATERIALS HORIZONS (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Rapid-Fabricated and Recoverable Dual-Network Hydrogel with Inherently Anti-Bacterial Abilities for Potential Adhesive Dressings

Kun Lei et al.

Summary: The study introduces injectable and recoverable dual-network hydrogels with excellent physicochemical properties and biocompatibility, making them a promising candidate for potential wound dressings. The hydrogels, based on PLL-g-HPA and Aga, exhibit fast gelation time, connective pore structure, good formability, and superior stability in extreme conditions. Additionally, the hydrogels have a helical structure and antibacterial ability, making them suitable for tissue attachment and preventing bacterial infection.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹
Article Medicine, Research & Experimental

Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg2+/curcumin from injectable self-healing hydrogels

Baojun Chen et al.

Summary: A composite hydrogel was developed for promoting rotator cuff tendon-to-bone healing through sustained release of curcumin and Mg2+, demonstrating significant anti-inflammatory and pro-differentiation effects. The hydrogel exhibited excellent biocompatibility and injectability, and enhanced tendon-to-bone healing in a rat model of rotator cuff tear at 8 weeks post-surgery.

THERANOSTICS (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

A Multifunctional Pro-Healing Zwitterionic Hydrogel for Simultaneous Optical Monitoring of pH and Glucose in Diabetic Wound Treatment

Yingnan Zhu et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

A Novel Double-Crosslinking-Double-Network Design for Injectable Hydrogels with Enhanced Tissue Adhesion and Antibacterial Capability for Wound Treatment

Lei Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

Self-Hydrophobization in a Dynamic Hydrogel for Creating Nonspecific Repeatable Underwater Adhesion

Lu Han et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹
Article Biochemistry & Molecular Biology

Anti-Infective and Pro-Coagulant Chitosan-Based Hydrogel Tissue Adhesive for Sutureless Wound Closure

Xinchen Du et al.

BIOMACROMOLECULES (2020)

添加到收藏夹
Article Multidisciplinary Sciences

Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function

Ji Hyun Kim et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹
Article Nanoscience & Nanotechnology

Green Gas-Mediated Cross-Linking Generates Biomolecular Hydrogels with Enhanced Strength and Excellent Hemostasis for Wound Healing

Zijian Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹
Article Biochemistry & Molecular Biology

Preparation and characterization of carboxymethyl chitosan/collagen peptide/oxidized konjac composite hydrogel

Chang Zhang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

Rapid Fabrication of Self-Healing, Conductive, and Injectable Gel as Dressings for Healing Wounds in Stretchable Parts of the Body

Sixiang Li et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

Liquid Bandage Harvests Robust Adhesive, Hemostatic, and Antibacterial Performances as a First-Aid Tissue Adhesive

Yufei Ma et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹
Review Chemistry, Applied

Hyaluronic acid-Based wound dressings: A review

Mariana F. P. Graca et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹
Article Chemistry, Applied

Supramolecular hydrogels based on cellulose for sustained release of therapeutic substances with antimicrobial and wound healing properties

Oscar Forero-Doria et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹
Article Chemistry, Applied

Construction of functional curdlan hydrogels with bio-inspired polydopamine for synergistic periodontal antibacterial therapeutics

Xianqin Tong et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹
Article Nanoscience & Nanotechnology

Injectable Adhesive Self-Healing Multicross-Linked Double-Network Hydrogel Facilitates Full-Thickness Skin Wound Healing

Bo Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹
Article Engineering, Biomedical

Biofilm-inspired adhesive and antibacterial hydrogel with tough tissue integration performance for sealing hemostasis and wound healing

Wei Han et al.

BIOACTIVE MATERIALS (2020)

添加到收藏夹
Article Biophysics

MoS2-ALG-Fe/GOx hydrogel with Fenton catalytic activity for combined cancer photothermal, starvation, and chemodynamic therapy

Lingling Zhou et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

添加到收藏夹
Article Chemistry, Applied

Tannic acid-reinforced methacrylated chitosan/methacrylated silk fibroin hydrogels with multifunctionality for accelerating wound healing

Xi He et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹
Article Chemistry, Applied

Mussel-inspired antimicrobial gelatin/chitosan tissue adhesive rapidly activated in situ by H2O2/ascorbic acid for infected wound closure

Xin Ye He et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹
Article Cell Biology

Healing potential of injectable Aloe vera hydrogel loaded by adipose-derived stem cell in skin tissue-engineering in a rat burn wound model

Ahmad Oryan et al.

CELL AND TISSUE RESEARCH (2019)

添加到收藏夹
Article Biophysics

A mussel-inspired carboxymethyl cellulose hydrogel with enhanced adhesiveness through enzymatic crosslinking

Yujie Zhong et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

添加到收藏夹
Review Biochemistry & Molecular Biology

A review on recent advances in chitosan based composite for hemostatic dressings

Munezza A. Khan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹
Article Materials Science, Biomaterials

In situ formed collagen-hyaluronic acid hydrogel as biomimetic dressing for promoting spontaneous wound healing

Huiyan Ying et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

添加到收藏夹
Article Surgery

The Surgical Suture

Miriam Byrne et al.

AESTHETIC SURGERY JOURNAL (2019)

添加到收藏夹
Article Engineering, Environmental

Degradable conductive injectable hydrogels as novel antibacterial, anti-oxidant wound dressings for wound healing

Jin Qu et al.

CHEMICAL ENGINEERING JOURNAL (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Skin-Inspired Antibacterial Conductive Hydrogels for Epidermal Sensors and Diabetic Foot Wound Dressings

Yue Zhao et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

添加到收藏夹
Review Engineering, Biomedical

Natural Polymer-Based Hydrogels with Enhanced Mechanical Performances: Preparation, Structure, and Property

Ziting Bao et al.

ADVANCED HEALTHCARE MATERIALS (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Tissue Tapes-Phenolic Hyaluronic Acid Hydrogel Patches for Off-the-Shelf Therapy

Jisoo Shin et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

添加到收藏夹
Article Biochemistry & Molecular Biology

Enhanced cutaneous wound healing by functional injectable thermo-sensitive chitosan-based hydrogel encapsulated human umbilical cord-mesenchymal stem cells

Hongjie Xu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Tough, Self-Healing Hydrogels Capable of Ultrafast Shape Changing

Zhen Jiang et al.

ADVANCED MATERIALS (2019)

添加到收藏夹
Article Engineering, Environmental

Preparation of therapeutic-laden konjac hydrogel for tumor combination therapy

Yiyun Liu et al.

CHEMICAL ENGINEERING JOURNAL (2019)

添加到收藏夹
Article Materials Science, Biomaterials

Injectable hydrogel composed of hydrophobically modified chitosan/oxidized-dextran for wound healing

Xinchen Du et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

添加到收藏夹
Article Engineering, Biomedical

In-situ doping of a conductive hydrogel with low protein absorption and bacterial adhesion for electrical stimulation of chronic wounds

Yuhui Lu et al.

ACTA BIOMATERIALIA (2019)

添加到收藏夹
Article Chemistry, Physical

Chitosan for gene delivery: Methods for improvement and applications

Di Chuan et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2019)

添加到收藏夹
Review Chemistry, Multidisciplinary

Nanomaterials with a photothermal effect for antibacterial activities: an overview

Jing-Wei Xu et al.

NANOSCALE (2019)

添加到收藏夹
Article Materials Science, Biomaterials

A DOPA-functionalized chondroitin sulfate-based adhesive hydrogel as a promising multi-functional bioadhesive

Wenzhen Zhu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

添加到收藏夹
Article Engineering, Biomedical

Injectable antibacterial conductive hydrogels with dual response to an electric field and pH for localized smart drug release

Jin Qu et al.

ACTA BIOMATERIALIA (2018)

添加到收藏夹
Review Pharmacology & Pharmacy

Drug delivery systems and materials for wound healing applications

Saghi Saghazadeh et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

添加到收藏夹
Article Engineering, Biomedical

Mussel-inspired degradable antibacterial polydopamine/silica nanoparticle for rapid hemostasis

Chunyu Liu et al.

BIOMATERIALS (2018)

添加到收藏夹
Article Chemistry, Applied

Dextran hydrogels incorporated with bioactive glass-ceramic: Nanocomposite scaffolds for bone tissue engineering

Parisa Nikpour et al.

CARBOHYDRATE POLYMERS (2018)

添加到收藏夹
Article Biochemistry & Molecular Biology

Mussel-inspired fabrication of konjac glucomannan/microcrystalline cellulose intelligent hydrogel with pH-responsive sustained release behavior

Lin Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

添加到收藏夹
Review Chemistry, Multidisciplinary

A functional chitosan-based hydrogel as a wound dressing and drug delivery system in the treatment of wound healing

He Liu et al.

RSC ADVANCES (2018)

添加到收藏夹
Article Cell Biology

Comprehensive Quantification of the Modified Proteome Reveals Oxidative Heart Damage in Mitochondrial Heteroplasmy

Navratan Bagwan et al.

CELL REPORTS (2018)

添加到收藏夹
Review Polymer Science

Hyaluronic Acid in the Third Millennium

Arianna Fallacara et al.

POLYMERS (2018)

添加到收藏夹
Article Nanoscience & Nanotechnology

Mussel-Inspired Tissue-Adhesive Hydrogel Based on the Polydopamine-Chondroitin Sulfate Complex for Growth-Factor-Free Cartilage Regeneration

Lu Han et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹
Article Chemistry, Multidisciplinary

A Cooperative Copper Metal-Organic Framework-Hydrogel System Improves Wound Healing in Diabetes

Jisheng Xiao et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

添加到收藏夹
Article Biotechnology & Applied Microbiology

Comparison of process technologies for chitosan production from shrimp shell waste: A techno-economic approach using Aspen Plus®

David Gomez-Rios et al.

FOOD AND BIOPRODUCTS PROCESSING (2017)

添加到收藏夹
Review Polymer Science

Hyaluronic Acid-Based Biomaterials: A Versatile and Smart Approach to Tissue Regeneration and Treating Traumatic, Surgical, and Chronic Wounds

Zahid Hussain et al.

POLYMER REVIEWS (2017)

添加到收藏夹
Article Respiratory System

Clinical and radiological characteristics of patients with late-onset severe restrictive lung defect after hematopoietic stem cell transplantation

Ho Namkoong et al.

BMC PULMONARY MEDICINE (2017)

添加到收藏夹
Article Materials Science, Biomaterials

Bilayered nanofibrous 3D hierarchy as skin rudiment by emulsion electrospinning for burn wound management

Pallabi Pal et al.

BIOMATERIALS SCIENCE (2017)

添加到收藏夹
Article Engineering, Biomedical

Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing

Xin Zhao et al.

BIOMATERIALS (2017)

添加到收藏夹
Article Biophysics

Feather keratin hydrogel for wound repair: Preparation, healing effect and biocompatibility evaluation

Ju Wang et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

添加到收藏夹
Article Nanoscience & Nanotechnology

Self-Healing Conductive Injectable Hydrogels with Antibacterial Activity as Cell Delivery Carrier for Cardiac Cell Therapy

Ruonan Dong et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

添加到收藏夹
Article Biophysics

Study of stiffness effects of poly(amidoamine)-poly(n-isopropyl acrylamide) hydrogel on wound healing

Shixuan Chen et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2016)

添加到收藏夹
Review Polymer Science

Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications

Marta Szekalska et al.

INTERNATIONAL JOURNAL OF POLYMER SCIENCE (2016)

添加到收藏夹
Article Surgery

Mechanical Strength and Rheological Properties of Tissue Adhesives With Regard to Colorectal Anastomosis An Ex Vivo Study

Konstantinos Aristotelis Vakalopoulos et al.

ANNALS OF SURGERY (2015)

添加到收藏夹
Review Materials Science, Multidisciplinary

Stimulus-responsive hydrogels: Theory, modern advances, and applications

Michael C. Koetting et al.

MATERIALS SCIENCE & ENGINEERING R-REPORTS (2015)

添加到收藏夹
Article Multidisciplinary Sciences

Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing

Shixuan Chen et al.

SCIENTIFIC REPORTS (2015)

添加到收藏夹
Article Materials Science, Biomaterials

A laminin mimetic peptide SIKVAV-conjugated chitosan hydrogel promoting wound healing by enhancing angiogenesis, re-epithelialization and collagen deposition

Shixuan Chen et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

添加到收藏夹
Article Engineering, Biomedical

Chitosan-based dressings loaded with neurotensin-an efficient strategy to improve early diabetic wound healing

Liane I. F. Moura et al.

ACTA BIOMATERIALIA (2014)

添加到收藏夹
Article Chemistry, Applied

A novel thermo-sensitive hydrogel based on thiolated chitosan/hydroxyapatite/beta-glycerophosphate

Xujie Liu et al.

CARBOHYDRATE POLYMERS (2014)

添加到收藏夹
Review Chemistry, Multidisciplinary

Self-healing gels based on constitutional dynamic chemistry and their potential applications

Zhao Wei et al.

CHEMICAL SOCIETY REVIEWS (2014)

添加到收藏夹
Article Materials Science, Paper & Wood

Hemostatic efficacy and tissue reaction of oxidized regenerated cellulose hemostats

Richard W. Hutchinson et al.

CELLULOSE (2013)

添加到收藏夹
Article Nanoscience & Nanotechnology

Bi-Layer Composite Dressing of Gelatin Nanofibrous Mat and Poly Vinyl Alcohol Hydrogel for Drug Delivery and Wound Healing Application: In-Vitro and In-Vivo Studies

Maneesh Jaiswal et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2013)

添加到收藏夹
Article Multidisciplinary Sciences

Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix

Mikael M. Martino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

添加到收藏夹
Article Chemistry, Multidisciplinary

Therapeutic application of injectable thermosensitive hydrogel in preventing local breast cancer recurrence and improving incision wound healing in a mouse model

Na Lei et al.

NANOSCALE (2012)

添加到收藏夹
Article Pathology

Swine as Models in Biomedical Research and Toxicology Testing

M. M. Swindle et al.

VETERINARY PATHOLOGY (2012)

添加到收藏夹
Article Chemistry, Multidisciplinary

Hyaluronic Acid Hydrogels for Biomedical Applications

Jason A. Burdick et al.

ADVANCED MATERIALS (2011)

添加到收藏夹
Article Chemistry, Applied

Chemical, physical and biological properties of alginates and their biomedical implications

Kurt I. Draget et al.

FOOD HYDROCOLLOIDS (2011)

添加到收藏夹
Review Biochemical Research Methods

Tissue engineering tools for modulation of the immune response

Ryan M. Boehler et al.

BIOTECHNIQUES (2011)

添加到收藏夹
Review Biotechnology & Applied Microbiology

Novel chitin and chitosan nanofibers in biomedical applications

R. Jayakumar et al.

BIOTECHNOLOGY ADVANCES (2010)

添加到收藏夹
Article Chemistry, Applied

Adjustment of the antibacterial activity and biocompatibility of hydroxypropyltrimethyl ammonium chloride chitosan by varying the degree of substitution of quaternary ammonium

Zhao-Xiang Peng et al.

CARBOHYDRATE POLYMERS (2010)

添加到收藏夹
Article Materials Science, Multidisciplinary

Novel carboxymethyl derivatives of chitin and chitosan materials and their biomedical applications

R. Jayakumar et al.

PROGRESS IN MATERIALS SCIENCE (2010)

添加到收藏夹
Review Cell Biology

Electrical fields in wound healing-An overriding signal that directs cell migration

Min Zhao

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)

添加到收藏夹
Article Engineering, Biomedical

Effect of chitosan molecular weight and deacetylation degree on Hemostasis

Jian Yang et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2008)

添加到收藏夹
Article Chemistry, Physical

Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration

Dong-An Wang et al.

NATURE MATERIALS (2007)

添加到收藏夹
Review Engineering, Biomedical

Chitosan: A versatile biopolymer for orthopaedic tissue-engineering

A Di Martino et al.

BIOMATERIALS (2005)

添加到收藏夹
Article Engineering, Biomedical

Immobilization of laminin peptide in molecularly aligned chitosan by covalent bonding

A Matsuda et al.

BIOMATERIALS (2005)

添加到收藏夹
Article Biochemistry & Molecular Biology

Controlling rigidity and degradation of alginate hydrogels via molecular weight distribution

HJ Kong et al.

BIOMACROMOLECULES (2004)

添加到收藏夹
Review Biochemistry & Molecular Biology

Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate

K Sugahara et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2003)

添加到收藏夹
Article Biochemistry & Molecular Biology

Chitosan enhances platelet adhesion and aggregation

TC Chou et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

添加到收藏夹
Review Chemistry, Medicinal

Alginate in drug delivery systems

HH Tonnesen et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2002)

添加到收藏夹
研讨会 海报 问题 讨论圈 基金 期刊 论文 科研社交 资讯集成 审稿人 关于我们 常见问题 移动App 隐私条款 使用条款
© Peeref 2019-2024. All rights reserved.