AMPK knocks at the gate of GATOR

Dai and colleagues show that activation of AMPK by glucose starvation leads to phosphorylation of GATOR2 and affects nutrient-dependent activation of mTORC1.

Automated summary

Dai and colleagues demonstrate that glucose starvation stimulates AMPK activation, which in turn phosphorylates GATOR2 and influences nutrient-dependent activation of mTORC1.