☆ 4.5 Article

Acute severe hepatitis as a presenting symptom in clinically stable patients admitted with SARS-CoV-2 Omicron infection

HEPATOLOGY COMMUNICATIONS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Immunology

ADAM Metalloproteinase Domain 17 Regulates Cholestasis-Associated Liver Injury and Sickness Behavior Development in Mice

Wagdi Almishri et al.

Summary: Increased expression of ADAM17 is observed in cholestatic liver diseases. Inhibition of ADAM17 activity improves liver injury and associated sickness behavior development, suggesting that ADAM17 inhibition may be a potential therapeutic approach for patients with cholestatic liver diseases.

FRONTIERS IN IMMUNOLOGY (2022)

添加到收藏夹

Article Infectious Diseases

Investigation into cases of hepatitis of unknown aetiology among young children, Scotland, 1 January 2022 to 12 April 2022

Kimberly Marsh et al.

Summary: On March 31, 2022, a cluster of severe hepatitis cases in children was reported in Scotland, with a total of 13 cases identified so far. Investigations are ongoing and new cases are still being discovered.

EUROSURVEILLANCE (2022)

添加到收藏夹

Editorial Material Medicine, General & Internal

Acute hepatitis of unknown origin in children

Muge Cevik et al.

BMJ-BRITISH MEDICAL JOURNAL (2022)

添加到收藏夹

Letter Gastroenterology & Hepatology

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens

Petter Brodin et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2022)

添加到收藏夹

Article Endocrinology & Metabolism

Molecular consequences of SARS-CoV-2 liver tropism

Nicola Wanner et al.

Summary: The study provides evidence for the hepatic tropism of SARS-CoV-2 and its impact on liver injury in COVID-19 patients. The researchers found viral RNA in autopsy liver specimens and successfully isolated infectious SARS-CoV-2 from liver tissue postmortem. The study also reveals similarities between the liver signatures of COVID-19 and other viral infections.

NATURE METABOLISM (2022)

添加到收藏夹

Review Radiology, Nuclear Medicine & Medical Imaging

Pathophysiology and Imaging Findings of COVID-19 Infection: An Organ-system Based Review

K. M. Capaccione et al.

Summary: COVID-19 infection can involve multiple organ systems throughout the body, with pulmonary findings being the most common but extrapulmonary manifestations also important; familiarity with the underlying pathophysiology and imaging characteristics is essential for radiologists to recognize these findings in COVID-19 patients.

ACADEMIC RADIOLOGY (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

COVID-19 and liver disease: mechanistic and clinical perspectives

Thomas Marjot et al.

Summary: This article provides insights into the mechanistic and clinical aspects of COVID-19 in the context of liver disease, discussing viral hepatotropism, differential expression of viral receptors on liver cell types, and liver histology features in COVID-19 patients. It also highlights the impact of COVID-19 on patients with pre-existing chronic liver disease and the potential strategies for managing these patients, including vaccination.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Liver involvement in children with SARS-COV-2 infection: Two distinct clinical phenotypes caused by the same virus

Adriana Perez et al.

Summary: Elevated ALT in children with SARS-CoV-2 is associated with a more severe disease course, including higher rates of multiorgan dysfunction and longer hospitalizations. Male gender and Black race were more likely to be associated with elevated ALT in MIS-C.

LIVER INTERNATIONAL (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier

Lael M. Yonker et al.

Summary: In children with MIS-C, prolonged presence of SARS-CoV-2 in the GI tract led to the release of zonulin, a biomarker of intestinal permeability, and subsequent trafficking of SARS-CoV-2 antigens into the bloodstream, resulting in hyperinflammation. Treatment with larazotide, a zonulin antagonist, reduced plasma SARS-CoV-2 spike antigen levels and inflammatory markers in a patient with MIS-C, leading to clinical improvement beyond current available treatments. These mechanistic insights provide potential targets for diagnosing, treating, and preventing MIS-C in children.

JOURNAL OF CLINICAL INVESTIGATION (2021)

添加到收藏夹

Article Medicine, General & Internal

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

Dawei Wang et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

添加到收藏夹

Article Medicine, General & Internal

Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series

Xiao-Wei Xu et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Acute Liver Injury in COVID-19: Prevalence and Association with Clinical Outcomes in a Large US Cohort

Meaghan M. Phipps et al.

HEPATOLOGY (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

Yijin Wang et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Abnormal Liver Function Tests in Patients WithCOVID-19: Relevance and Potential Pathogenesis

Anna Bertolini et al.

HEPATOLOGY (2020)

添加到收藏夹

Letter Gastroenterology & Hepatology

COVID-19 and the liver: little cause for concern

Mansoor N. Bangash et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

COVID-19 and the liver

Dinesh Jothimani et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

Mary Hongying Cheng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.