Association of Multiple Cardiovascular Risk Factors with Musculoskeletal Function in Acute Coronary Syndrome Ward Inpatients

This study explored the association of multiple risk factors with musculoskeletal function in adults hospitalized for acute coronary syndrome. Sixty-nine inpatients (55 +/- 6 years; 67% male) admitted to the cardiology ward within <12 h were assessed regarding stress, smoking, alcoholism, hypertension, diabetes mellitus, and obesity. The musculoskeletal function was assessed by predicted values of handgrip strength of the dominant hand (HGS-D-%) and maximal inspiratory and expiratory pressures (MIP% and MEP%, respectively). After adjustment by age and sex, drinking habits showed the strongest linear association with the total number of cardiovascular disease risk factors [standardized beta, p-value] (beta = 0.110, p < 0.001), followed by smoking load (beta = 0.028, p = 0.009). Associations were also observed for HGS-D-% with mean blood pressure (beta = 0.019 [0.001; 0.037], p = 0.048); MIP% with mean blood pressure (beta = 0.025 [0.006; 0.043], p = 0.013); and MEP% with drinking habits (beta = 0.009 [0.002; 0.016], p = 0.013) and body mass index (beta = 0.008 [0.000; 0.015], p = 0.035). Peripheral and respiratory muscle strength must be interpreted in the context of its association with cardiovascular disease risk factors in adults hospitalized for acute coronary syndrome.

Automated summary

This study explored the association between multiple risk factors and musculoskeletal function in adults hospitalized for acute coronary syndrome. The strongest linear association was found between drinking habits and the total number of cardiovascular disease risk factors, followed by smoking load. Furthermore, handgrip strength and respiratory muscle strength were associated with mean blood pressure, drinking habits, and body mass index.