期刊
HEALTHCARE
卷 11, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/healthcare11081148
关键词
hypoxic-ischemic brain injury; Coma Recovery Scale-Revised; thalamocortical tract; diffusion tensor tractography; diffusion tensor imaging
This pilot study investigated the relationship between the Coma Recovery Scale-Revised (CRS-R) and the five subparts of the thalamocortical tract in chronic patients with hypoxic-ischemic brain injury using diffusion tensor tractography (DTT). The results showed a moderate positive correlation between the CRS-R score and the tract volume of the prefrontal cortex part, and the change in the remaining number of neural fibers of the prefrontal cortex part appeared to be related to the change in conscious state.
Background: This pilot study examined the relationship between the Coma Recovery Scale-Revised (CRS-R) and the five subparts of the thalamocortical tract in chronic patients with hypoxic-ischemic brain injury by diffusion tensor tractography (DTT). Methods: Seventeen consecutive chronic patients with hypoxic-ischemic brain injury were recruited. The consciousness state was evaluated using CRS-R. The five subparts of the thalamocortical tract (the prefrontal cortex, the premotor cortex, the primary motor cortex, the primary somatosensory cortex, and the posterior parietal cortex) were reconstructed using DTT. Fractional anisotropy and the tract volume of each subpart of the thalamocortical tract were estimated. Results: The CRS-R score showed a moderate positive correlation with the tract volume of the prefrontal cortex part of the thalamocortical tract (p < 0.05). In addition, the tract volume of the prefrontal cortex component of the thalamocortical tract could explain the variability in the CRS-R score (p < 0.05). Conclusion: The prefrontal cortex part was closely related to the CRS-R score in chronic patients with hypoxic-ischemic brain injury. In addition, the change in the remaining number of neural fibers of the prefrontal cortex part appeared to be related to the change in conscious state.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据