期刊
CHILDREN-BASEL
卷 10, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/children10050829
关键词
osteoid osteoma; arthritis; child; joint pain; synovitis; juvenile idiopathic arthritis; rheumatic diseases; bone tumor; imaging; diagnosis
类别
Intra- and juxta-articular osteoid osteomas are rare and can mimic inflammatory monoarthritis. The diagnostic delay can be long, and misdiagnosis is common, especially in unusual sites. Knowledge of the atypical presentations and pitfalls is crucial for accurate diagnosis.
Background: Intra- and juxta-articular osteoid osteomas are rare, representing less than 10% of all osteomas. Compared to the classic diaphyseal or metaphyseal site of long bones, they often have an atypical onset, a longest diagnostic delay, and frequent initial misdiagnoses, with pictures that can mimic inflammatory monoarthritis. We aimed to describe a case series, and to provide a literature review of this uncommon and misleading tumor location. Methods: We performed a retrospective analysis of patients referred to three pediatric rheumatology centers, with a final diagnosis of articular osteoid osteoma. A review of the literature was additionally conducted. Results: We included 10 patients with a mean age of 14 years. All patients with unusual sites (olecranon fossa, lumbar vertebra, distal phalanx of the toe, fibula) had a misdiagnosis, and cases with initial suspicion of monoarthritis had the longest diagnostic delay, up to 24 months. The literature review confirms the significant risk of misdiagnosis, and an average time from symptom onset to diagnosis ranging from 0.4 to 1.8 years. Conclusions: Articular osteoid osteoma may mimic arthritis, especially in adolescence. Knowledge of the atypical forms of presentation, and of the clinical and radiological pitfalls, reduces the risk of diagnostic error.
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